SCOP 1.65: Family b.22.1.1: TNF-like

Lineage for Family b.22.1.1: TNF-like

1. Root: SCOP 1.65

2. Class b: All beta proteins [48724] (126 folds)

3. Fold b.22: TNF-like [49841] (1 superfamily)
   sandwich, 10 strands in 2 sheets; jelly-roll

4. Superfamily b.22.1: TNF-like [49842] (1 family)

5. Family b.22.1.1: TNF-like [49843] (7 proteins)

Proteins:

1. 30 kd adipocyte complement-related protein [49846] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [49847] (1 PDB entry)

2. Apoptosis-2 ligand, apo2l/TRAIL [49851] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49852] (5 PDB entries)

3. Collagen X NC1 trimerisation domain [69230] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69231] (1 PDB entry)

4. Extracellular domain of CD40 ligand [49844] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49845] (2 PDB entries)

5. Soluble part of TALL-1, sTALL-1 (BAFF) [69228] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69229] (6 PDB entries)
     also includes the PDB entry (1otz) that together with the entry (1p0t) provides the multimeric structure of the complex of this protein with its receptor, BAFF-R. In these entries protein chains are designated by both upper case and lower case letters creating problems with its processing and presentation in SCOP

6. TRANCE/RANKL cytokine [63721] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [63722] (2 PDB entries)

7. Tumor necrosis factor (TNF) [49848] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [49849] (6 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [49850] (1 PDB entry)

More info for Family b.22.1.1: TNF-like

Timeline for Family b.22.1.1: TNF-like:

• Family b.22.1.1: TNF-like first appeared (with stable ids) in SCOP 1.55
  
• Family b.22.1.1: TNF-like appears in SCOP 1.63
  
• Family b.22.1.1: TNF-like appears in SCOP 1.67
  
• Family b.22.1.1: TNF-like appears in the current release, SCOPe 2.08