Lineage for Family b.7.1.2: Synaptotagmin-like (S variant)

  1. Root: SCOPe 2.07
  2. 2352458Class b: All beta proteins [48724] (178 folds)
  3. 2382505Fold b.7: C2 domain-like [49561] (5 superfamilies)
    sandwich; 8 strands in 2 sheets; greek-key
  4. 2382506Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families) (S)
    two constituent families are related by circular permutation
  5. 2382667Family b.7.1.2: Synaptotagmin-like (S variant) [49575] (11 proteins)
    topologically similar to the C-terminal domain of PapD

Proteins:

  1. 2382668C2 domain from protein kinase c (alpha) [49578] (1 species)
  2. 2382677C2 domain from protein kinase c (beta) [49580] (1 species)
  3. 2382681C2 domain protein At1g63220 [117082] (1 species)
  4. C2b-domain of rabphilin [49582] (1 species)
  5. 2382687Piccolo [101566] (1 species)
  6. 2382690Regulating synaptic membrane exocytosis protein, rim2 [101564] (1 species)
  7. 2382693Synaptogamin I [49576] (3 species)
    duplication: contains tandem repeat of two similar domains
    1. 2382694Species Human (Homo sapiens) [TaxId:9606] [158946] (14 PDB entries)
    2. 2382714Species Mouse (Mus musculus) [TaxId:10090] [335436] (5 PDB entries)
    3. 2382721Species Norway rat (Rattus norvegicus) [TaxId:10116] [49577] (12 PDB entries)
      Uniprot P21707 271-419 ! Uniprot P21707 271-419
  8. 2382738Synaptotagmin III [109606] (1 species)
    duplication: contains 2 C2 domains
  9. 2382742Synaptotagmin IV [101562] (2 species)
    duplication: contains 2 C2 domains
    1. 2382743Species Human (Homo sapiens) [TaxId:9606] [101563] (1 PDB entry)
    2. 2382745Species Norway rat (Rattus norvegicus) [TaxId:10116] [110115] (2 PDB entries)
      Uniprot P50232 288-425
  10. 2382748Synaptotagmin XIII [117084] (1 species)
  11. 2382751automated matches [190234] (2 species)
    not a true protein
    1. 2382752Species Human (Homo sapiens) [TaxId:9606] [188037] (3 PDB entries)
    2. 2382758Species Norway rat (Rattus norvegicus) [TaxId:10116] [186999] (6 PDB entries)

More info for Family b.7.1.2: Synaptotagmin-like (S variant)

Timeline for Family b.7.1.2: Synaptotagmin-like (S variant):