SCOPe 2.05: Family b.7.1.2: Synaptotagmin-like (S variant)

Lineage for Family b.7.1.2: Synaptotagmin-like (S variant)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.7: C2 domain-like [49561] (5 superfamilies)
   sandwich; 8 strands in 2 sheets; greek-key

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families)
   two constituent families are related by circular permutation

5. Family b.7.1.2: Synaptotagmin-like (S variant) [49575] (11 proteins)
   topologically similar to the C-terminal domain of PapD

Proteins:

1. C2 domain from protein kinase c (alpha) [49578] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [49579] (5 PDB entries)

2. C2 domain from protein kinase c (beta) [49580] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [49581] (1 PDB entry)

3. C2 domain protein At1g63220 [117082] (1 species)

   • Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [117083] (1 PDB entry)
     Uniprot Q9C8S6 2-125

4. C2b-domain of rabphilin [49582] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [49583] (1 PDB entry)

5. Piccolo [101566] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [101567] (1 PDB entry)

6. Regulating synaptic membrane exocytosis protein, rim2 [101564] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [101565] (1 PDB entry)

7. Synaptogamin I [49576] (2 species)
   duplication: contains tandem repeat of two similar domains

   1. Species Human (Homo sapiens) [TaxId:9606] [158946] (10 PDB entries)

   2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [49577] (7 PDB entries)
      Uniprot P21707 271-419 ! Uniprot P21707 271-419

8. Synaptotagmin III [109606] (1 species)
   duplication: contains 2 C2 domains

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [109607] (1 PDB entry)
     Uniprot P40748 293-588

9. Synaptotagmin IV [101562] (2 species)
   duplication: contains 2 C2 domains

   1. Species Human (Homo sapiens) [TaxId:9606] [101563] (1 PDB entry)

   2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [110115] (2 PDB entries)
      Uniprot P50232 288-425

10. Synaptotagmin XIII [117084] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [117085] (1 PDB entry)
      Uniprot Q7L8C5 155-280

11. automated matches [190234] (2 species)
    not a true protein

    1. Species Human (Homo sapiens) [TaxId:9606] [188037] (3 PDB entries)

    2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [186999] (6 PDB entries)

More info for Family b.7.1.2: Synaptotagmin-like (S variant)

Timeline for Family b.7.1.2: Synaptotagmin-like (S variant):

• Family b.7.1.2: Synaptotagmin-like (S variant) first appeared (with stable ids) in SCOP 1.55
  
• Family b.7.1.2: Synaptotagmin-like (S variant) appears in SCOPe 2.04
  
• Family b.7.1.2: Synaptotagmin-like (S variant) appears in SCOPe 2.06
  
• Family b.7.1.2: Synaptotagmin-like (S variant) appears in the current release, SCOPe 2.08