SCOP 1.69: Family b.7.1.2: Synaptotagmin-like (S variant)

Lineage for Family b.7.1.2: Synaptotagmin-like (S variant)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.7: C2 domain-like [49561] (4 superfamilies)
   sandwich; 8 strands in 2 sheets; greek-key

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (2 families)
   two constituent families are related by circular permutation

5. Family b.7.1.2: Synaptotagmin-like (S variant) [49575] (8 proteins)
   topologically similar to the C-terminal domain of PapD

Proteins:

1. C2 domain from protein kinase c (alpha) [49578] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [49579] (1 PDB entry)

2. C2 domain from protein kinase c (beta) [49580] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [49581] (1 PDB entry)

3. C2b-domain of rabphilin [49582] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [49583] (1 PDB entry)

4. Piccolo [101566] (1 species)

   • Species Rat (Rattus norvegicus ) [TaxId:10116] [101567] (1 PDB entry)

5. Regulating synaptic membrane exocytosis protein, rim2 [101564] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [101565] (1 PDB entry)

6. Synaptogamin I [49576] (1 species)
   duplication: contains tandem repeat of two similar domains

   • Species Rat (Rattus norvegicus) [TaxId:10116] [49577] (6 PDB entries)

7. Synaptotagmin III [109606] (1 species)
   duplication: contains 2 C2 domains

   • Species Rat (Rattus norvegicus) [TaxId:10116] [109607] (1 PDB entry)

8. Synaptotagmin IV [101562] (2 species)
   duplication: contains 2 C2 domains

   1. Species Human (Homo sapiens) [TaxId:9606] [101563] (1 PDB entry)

   2. Species Rat (Rattus norvegicus) [TaxId:10116] [110115] (2 PDB entries)

More info for Family b.7.1.2: Synaptotagmin-like (S variant)

Timeline for Family b.7.1.2: Synaptotagmin-like (S variant):

• Family b.7.1.2: Synaptotagmin-like (S variant) first appeared (with stable ids) in SCOP 1.55
  
• Family b.7.1.2: Synaptotagmin-like (S variant) appears in SCOP 1.67
  
• Family b.7.1.2: Synaptotagmin-like (S variant) appears in SCOP 1.71
  
• Family b.7.1.2: Synaptotagmin-like (S variant) appears in the current release, SCOPe 2.08