SCOPe 2.02: Protein: Phoshoinositide 3-kinase (PI3K)

Lineage for Protein: Phoshoinositide 3-kinase (PI3K)

Root: SCOPe 2.02
Class b: All beta proteins [48724] (174 folds)
Fold b.7: C2 domain-like [49561] (5 superfamilies)
sandwich; 8 strands in 2 sheets; greek-key
Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families)
two constituent families are related by circular permutation
Family b.7.1.1: PLC-like (P variant) [49563] (12 proteins)
Protein Phoshoinositide 3-kinase (PI3K) [49570] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [49572] (3 PDB entries)
1. Domain for 1e8y:
  - Domain d1e8ya2: 1e8y A:357-522 [23187]
    Other proteins in same PDB: d1e8ya1, d1e8ya3, d1e8ya4
2. Domain for 1e8z:
  - Domain d1e8za2: 1e8z A:357-522 [23188]
    Other proteins in same PDB: d1e8za1, d1e8za3, d1e8za4
    complexed with stu
3. Domain for 1he8:
  - Domain d1he8a2: 1he8 A:353-524 [23189]
    Other proteins in same PDB: d1he8a1, d1he8a3, d1he8a4, d1he8b_
    complexed with gnp, mg
Pig (Sus scrofa) [TaxId:9823] [49571] (5 PDB entries)
1. Domain for 1e7u:
  - Domain d1e7ua2: 1e7u A:351-524 [23182]
    Other proteins in same PDB: d1e7ua1, d1e7ua3, d1e7ua4
    complexed with kwt
2. Domain for 1e7v:
  - Domain d1e7va2: 1e7v A:354-524 [23184]
    Other proteins in same PDB: d1e7va1, d1e7va3, d1e7va4
    complexed with ly2
3. Domain for 1e8w:
  - Domain d1e8wa2: 1e8w A:352-524 [23186]
    Other proteins in same PDB: d1e8wa1, d1e8wa3, d1e8wa4
    complexed with que
4. Domain for 1e8x:
  - Domain d1e8xa2: 1e8x A:357-522 [23183]
    Other proteins in same PDB: d1e8xa1, d1e8xa3, d1e8xa4
    complexed with atp, lu
5. Domain for 1e90:
  - Domain d1e90a2: 1e90 A:357-521 [23185]
    Other proteins in same PDB: d1e90a1, d1e90a3, d1e90a4
    complexed with myc

More info for Protein Phoshoinositide 3-kinase (PI3K) from b.7.1.1: PLC-like (P variant)

Timeline for Protein Phoshoinositide 3-kinase (PI3K) from b.7.1.1: PLC-like (P variant):

Protein Phoshoinositide 3-kinase (PI3K) from b.7.1.1: PLC-like (P variant) first appeared (with stable ids) in SCOP 1.55
Protein Phoshoinositide 3-kinase (PI3K) from b.7.1.1: PLC-like (P variant) appears in SCOPe 2.01
Protein Phoshoinositide 3-kinase (PI3K) from b.7.1.1: PLC-like (P variant) appears in SCOPe 2.03
Protein Phoshoinositide 3-kinase (PI3K) from b.7.1.1: PLC-like (P variant) appears in the current release, SCOPe 2.08