SCOP 1.65: Family b.7.1.1: PLC-like (P variant)

Lineage for Family b.7.1.1: PLC-like (P variant)

1. Root: SCOP 1.65

2. Class b: All beta proteins [48724] (126 folds)

3. Fold b.7: C2 domain-like [49561] (4 superfamilies)
   sandwich; 8 strands in 2 sheets; greek-key

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (2 families)
   two constituent families are related by circular permutation

5. Family b.7.1.1: PLC-like (P variant) [49563] (6 proteins)

Proteins:

1. Domain from cytosolic phospholipase A2 [49566] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49567] (3 PDB entries)

2. Domain from protein kinase C delta [49573] (1 species)
   rudiment form lacking calcium-binding site

   • Species Rat (Rattus norvegicus) [TaxId:10116] [49574] (1 PDB entry)

3. Domain from protein kinase C epsilon [69196] (1 species)
   Calcium-independent

   • Species Rat (Rattus rattus) [TaxId:10117] [69197] (1 PDB entry)

4. Phoshoinositide 3-kinase (PI3K) [49570] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [49572] (3 PDB entries)

   2. Species Pig (Sus scrofa) [TaxId:9823] [49571] (5 PDB entries)

5. PI-specific phospholipase C isozyme D1 (PLC-D1), C-terminal domain [49564] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [49565] (10 PDB entries)

6. Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain [49568] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49569] (1 PDB entry)

More info for Family b.7.1.1: PLC-like (P variant)

Timeline for Family b.7.1.1: PLC-like (P variant):

• Family b.7.1.1: PLC-like (P variant) first appeared (with stable ids) in SCOP 1.55
  
• Family b.7.1.1: PLC-like (P variant) appears in SCOP 1.63
  
• Family b.7.1.1: PLC-like (P variant) appears in SCOP 1.67
  
• Family b.7.1.1: PLC-like (P variant) appears in the current release, SCOPe 2.08