SCOPe 2.08: Protein: Acute myeloid leukemia 1 protein (AML1), RUNT domain

Lineage for Protein: Acute myeloid leukemia 1 protein (AML1), RUNT domain

Root: SCOPe 2.08
Class b: All beta proteins [48724] (180 folds)
Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
Superfamily b.2.5: p53-like transcription factors [49417] (8 families)
Family b.2.5.6: RUNT domain [81318] (2 proteins)
automatically mapped to Pfam PF00853
Protein Acute myeloid leukemia 1 protein (AML1), RUNT domain [49439] (2 species)
synonym: core binding factor alpha, cbfa

Species:

Human (Homo sapiens) [TaxId:9606] [49440] (5 PDB entries)
1. Domain for 1cmo:
  - Domain d1cmoa_: 1cmo A: [22462]
2. Domain for 1co1:
  - Domain d1co1a_: 1co1 A: [22463]
3. Domains for 1e50:
  1. Domain d1e50a_: 1e50 A: [59244]
    Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
  2. Domain d1e50c_: 1e50 C: [59246]
    Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
  3. Domain d1e50e_: 1e50 E: [59248]
    Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
  4. Domain d1e50g_: 1e50 G: [59250]
    Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
  5. Domain d1e50q_: 1e50 Q: [59252]
    Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
  6. Domain d1e50r_: 1e50 R: [59253]
    Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
4. Domains for 1h9d:
  1. Domain d1h9da_: 1h9d A: [60821]
    Other proteins in same PDB: d1h9db_, d1h9dd_
  2. Domain d1h9dc_: 1h9d C: [60823]
    Other proteins in same PDB: d1h9db_, d1h9dd_
5. Domains for 1ljm:
  1. Domain d1ljma_: 1ljm A: [78051]
    complexed with cl
  2. Domain d1ljmb_: 1ljm B: [78052]
    complexed with cl
Mouse (Mus musculus) [TaxId:10090] [63684] (14 PDB entries)
almost identical sequence to the human protein
1. Domain for 1ean:
  - Domain d1eana_: 1ean A: [76141]
    protein/DNA complex; complexed with cl
2. Domains for 1eao:
  1. Domain d1eaoa_: 1eao A: [76142]
    protein/DNA complex; complexed with br
  2. Domain d1eaob_: 1eao B: [76143]
    protein/DNA complex; complexed with br
3. Domains for 1eaq:
  1. Domain d1eaqa_: 1eaq A: [76144]
    protein/DNA complex; complexed with cl
  2. Domain d1eaqb_: 1eaq B: [76145]
    protein/DNA complex; complexed with cl
4. Domains for 1hjb:
  1. Domain d1hjbc_: 1hjb C: [61075]
    Other proteins in same PDB: d1hjba_, d1hjbb_, d1hjbd_, d1hjbe_
    protein/DNA complex
  2. Domain d1hjbf_: 1hjb F: [61078]
    Other proteins in same PDB: d1hjba_, d1hjbb_, d1hjbd_, d1hjbe_
    protein/DNA complex
5. Domains for 1hjc:
  1. Domain d1hjca_: 1hjc A: [61079]
    protein/DNA complex
  2. Domain d1hjcd_: 1hjc D: [61080]
    protein/DNA complex
6. Domain for 1io4:
  - Domain d1io4c_: 1io4 C: [62616]
    Other proteins in same PDB: d1io4a_, d1io4b_, d1io4d_
    protein/DNA complex; complexed with au
7. Domains for 3wts:
  1. Domain d3wtsa1: 3wts A:60-177 [259046]
    Other proteins in same PDB: d3wtsa2, d3wtsb_, d3wtsc_, d3wtsg_
    automated match to d1hjbc_
    protein/DNA complex
  2. Domain d3wtsf_: 3wts F: [262460]
    Other proteins in same PDB: d3wtsa2, d3wtsb_, d3wtsc_, d3wtsg_
    automated match to d1hjbc_
    protein/DNA complex
8. Domains for 3wtt:
  1. Domain d3wtta_: 3wtt A: [265770]
    Other proteins in same PDB: d3wttb_, d3wttc_, d3wttg_
    automated match to d1hjbc_
    protein/DNA complex
  2. Domain d3wttf_: 3wtt F: [265773]
    Other proteins in same PDB: d3wttb_, d3wttc_, d3wttg_
    automated match to d1hjbc_
    protein/DNA complex
9. Domains for 3wtu:
  1. Domain d3wtua_: 3wtu A: [259053]
    Other proteins in same PDB: d3wtub_, d3wtuc_, d3wtug_
    automated match to d1hjbc_
    protein/DNA complex
  2. Domain d3wtuf_: 3wtu F: [262463]
    Other proteins in same PDB: d3wtub_, d3wtuc_, d3wtug_
    automated match to d1hjbc_
    protein/DNA complex
10. Domains for 3wtv:
  1. Domain d3wtva_: 3wtv A: [259144]
    Other proteins in same PDB: d3wtvb_, d3wtvc_, d3wtvg_
    automated match to d1hjbc_
    protein/DNA complex
  2. Domain d3wtvf_: 3wtv F: [259147]
    Other proteins in same PDB: d3wtvb_, d3wtvc_, d3wtvg_
    automated match to d1hjbc_
    protein/DNA complex
11. Domains for 3wtw:
  1. Domain d3wtwa_: 3wtw A: [259149]
    Other proteins in same PDB: d3wtwb_, d3wtwc_, d3wtwg_
    automated match to d1hjbc_
    protein/DNA complex
  2. Domain d3wtwf_: 3wtw F: [259148]
    Other proteins in same PDB: d3wtwb_, d3wtwc_, d3wtwg_
    automated match to d1hjbc_
    protein/DNA complex
12. Domains for 3wtx:
  1. Domain d3wtxa_: 3wtx A: [265775]
    Other proteins in same PDB: d3wtxb_, d3wtxg_
    automated match to d1hjbc_
    protein/DNA complex
  2. Domain d3wtxf_: 3wtx F: [265777]
    Other proteins in same PDB: d3wtxb_, d3wtxg_
    automated match to d1hjbc_
    protein/DNA complex
13. Domains for 3wty:
  1. Domain d3wtya_: 3wty A: [259051]
    Other proteins in same PDB: d3wtyb_, d3wtyc_, d3wtyg_
    automated match to d1hjbc_
    protein/DNA complex
  2. Domain d3wtyf_: 3wty F: [262469]
    Other proteins in same PDB: d3wtyb_, d3wtyc_, d3wtyg_
    automated match to d1hjbc_
    protein/DNA complex
14. Domain for 3wu1:
  - Domain d3wu1a_: 3wu1 A: [259150]
    Other proteins in same PDB: d3wu1b_
    automated match to d1h9da_
    protein/DNA complex

More info for Protein Acute myeloid leukemia 1 protein (AML1), RUNT domain from b.2.5.6: RUNT domain

Timeline for Protein Acute myeloid leukemia 1 protein (AML1), RUNT domain from b.2.5.6: RUNT domain:

Protein Acute myeloid leukemia 1 protein (AML1), RUNT domain from b.2.5.6: RUNT domain first appeared (with stable ids) in SCOP 1.55, called Protein Acute myeloid leukemia 1 protein (AML1), RUNT domain from b.2.5.1: p53-like transcription factors
Protein Acute myeloid leukemia 1 protein (AML1), RUNT domain from b.2.5.6: RUNT domain appears in SCOPe 2.07