Lineage for Protein: Acute myeloid leukemia 1 protein (AML1), RUNT domain

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2033752Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
    sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
  4. 2034243Superfamily b.2.5: p53-like transcription factors [49417] (8 families) (S)
  5. 2034595Family b.2.5.6: RUNT domain [81318] (2 protein domains)
    automatically mapped to Pfam PF00853
  6. 2034596Protein Acute myeloid leukemia 1 protein (AML1), RUNT domain [49439] (2 species)
    synonym: core binding factor alpha, cbfa

Species:

  1. 2034597Human (Homo sapiens) [TaxId:9606] [49440] (5 PDB entries)
    1. Domain for 1cmo:
    2. Domain for 1co1:
    3. Domains for 1e50:
      1. 2034602Domain d1e50a_: 1e50 A: [59244]
        Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
      2. 2034603Domain d1e50c_: 1e50 C: [59246]
        Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
      3. 2034604Domain d1e50e_: 1e50 E: [59248]
        Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
      4. 2034605Domain d1e50g_: 1e50 G: [59250]
        Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
      5. 2034606Domain d1e50q_: 1e50 Q: [59252]
        Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
      6. 2034607Domain d1e50r_: 1e50 R: [59253]
        Other proteins in same PDB: d1e50b_, d1e50d_, d1e50f_, d1e50h_
    4. Domains for 1h9d:
      1. 2034600Domain d1h9da_: 1h9d A: [60821]
        Other proteins in same PDB: d1h9db_, d1h9dd_
        protein/DNA complex
      2. 2034601Domain d1h9dc_: 1h9d C: [60823]
        Other proteins in same PDB: d1h9db_, d1h9dd_
        protein/DNA complex
    5. Domains for 1ljm:
      1. 2034598Domain d1ljma_: 1ljm A: [78051]
        complexed with cl
      2. 2034599Domain d1ljmb_: 1ljm B: [78052]
        complexed with cl
  2. 2034610Mouse (Mus musculus) [TaxId:10090] [63684] (14 PDB entries)
    almost identical sequence to the human protein
    1. Domain for 1ean:
    2. Domains for 1eao:
      1. 2034613Domain d1eaoa_: 1eao A: [76142]
        complexed with br
      2. 2034614Domain d1eaob_: 1eao B: [76143]
        complexed with br
    3. Domains for 1eaq:
      1. 2034611Domain d1eaqa_: 1eaq A: [76144]
        complexed with cl
      2. 2034612Domain d1eaqb_: 1eaq B: [76145]
        complexed with cl
    4. Domains for 1hjb:
      1. 2034623Domain d1hjbc_: 1hjb C: [61075]
        Other proteins in same PDB: d1hjba_, d1hjbb_, d1hjbd_, d1hjbe_
        protein/DNA complex
      2. 2034624Domain d1hjbf_: 1hjb F: [61078]
        Other proteins in same PDB: d1hjba_, d1hjbb_, d1hjbd_, d1hjbe_
        protein/DNA complex
    5. Domains for 1hjc:
      1. 2034617Domain d1hjca_: 1hjc A: [61079]
        protein/DNA complex
      2. 2034618Domain d1hjcd_: 1hjc D: [61080]
        protein/DNA complex
    6. Domain for 1io4:
    7. Domains for 3wts:
      1. 2034621Domain d3wtsa1: 3wts A:60-177 [259046]
        Other proteins in same PDB: d3wtsa2, d3wtsb_, d3wtsc_, d3wtsg_
        automated match to d1hjbc_
        protein/DNA complex
      2. 2034622Domain d3wtsf_: 3wts F: [262460]
        Other proteins in same PDB: d3wtsa2, d3wtsb_, d3wtsc_, d3wtsg_
        automated match to d1hjbc_
        protein/DNA complex
    8. Domains for 3wtt:
      1. 2034619Domain d3wtta_: 3wtt A: [265770]
        Other proteins in same PDB: d3wttb_, d3wttc_, d3wttg_
        automated match to d1hjbc_
        protein/DNA complex
      2. 2034620Domain d3wttf_: 3wtt F: [265773]
        Other proteins in same PDB: d3wttb_, d3wttc_, d3wttg_
        automated match to d1hjbc_
        protein/DNA complex
    9. Domains for 3wtu:
      1. 2034627Domain d3wtua_: 3wtu A: [259053]
        Other proteins in same PDB: d3wtub_, d3wtuc_, d3wtug_
        automated match to d1hjbc_
        protein/DNA complex
      2. 2034628Domain d3wtuf_: 3wtu F: [262463]
        Other proteins in same PDB: d3wtub_, d3wtuc_, d3wtug_
        automated match to d1hjbc_
        protein/DNA complex
    10. Domains for 3wtv:
      1. 2034629Domain d3wtva_: 3wtv A: [259144]
        Other proteins in same PDB: d3wtvb_, d3wtvc_, d3wtvg_
        automated match to d1hjbc_
        protein/DNA complex
      2. 2034630Domain d3wtvf_: 3wtv F: [259147]
        Other proteins in same PDB: d3wtvb_, d3wtvc_, d3wtvg_
        automated match to d1hjbc_
        protein/DNA complex
    11. Domains for 3wtw:
      1. 2034634Domain d3wtwa_: 3wtw A: [259149]
        Other proteins in same PDB: d3wtwb_, d3wtwc_, d3wtwg_
        automated match to d1hjbc_
        protein/DNA complex
      2. 2034635Domain d3wtwf_: 3wtw F: [259148]
        Other proteins in same PDB: d3wtwb_, d3wtwc_, d3wtwg_
        automated match to d1hjbc_
        protein/DNA complex
    12. Domains for 3wtx:
      1. 2034632Domain d3wtxa_: 3wtx A: [265775]
        Other proteins in same PDB: d3wtxb_, d3wtxg_
        automated match to d1hjbc_
        protein/DNA complex
      2. 2034633Domain d3wtxf_: 3wtx F: [265777]
        Other proteins in same PDB: d3wtxb_, d3wtxg_
        automated match to d1hjbc_
        protein/DNA complex
    13. Domains for 3wty:
      1. 2034625Domain d3wtya_: 3wty A: [259051]
        Other proteins in same PDB: d3wtyb_, d3wtyc_, d3wtyg_
        automated match to d1hjbc_
        protein/DNA complex
      2. 2034626Domain d3wtyf_: 3wty F: [262469]
        Other proteins in same PDB: d3wtyb_, d3wtyc_, d3wtyg_
        automated match to d1hjbc_
        protein/DNA complex
    14. Domain for 3wu1:

More info for Protein Acute myeloid leukemia 1 protein (AML1), RUNT domain from b.2.5.6: RUNT domain

Timeline for Protein Acute myeloid leukemia 1 protein (AML1), RUNT domain from b.2.5.6: RUNT domain: