SCOPe 2.06: Family b.1.10.1: Alpha-adaptin ear subdomain-like

Lineage for Family b.1.10.1: Alpha-adaptin ear subdomain-like

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.10: Clathrin adaptor appendage domain [49348] (4 families)
   contains an additional N-terminal strand

5. Family b.1.10.1: Alpha-adaptin ear subdomain-like [49349] (2 proteins)
   ear domain consists of two different subdomains
   automatically mapped to Pfam PF02883

Proteins:

1. Alpha-adaptin AP2 ear domain, N-terminal subdomain [49350] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [49351] (10 PDB entries)
     Uniprot P17427 694-938 # 98% sequence identity

2. Beta2-adaptin AP2 ear domain, N-terminal subdomain [49352] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49353] (4 PDB entries)

More info for Family b.1.10.1: Alpha-adaptin ear subdomain-like

Timeline for Family b.1.10.1: Alpha-adaptin ear subdomain-like:

• Family b.1.10.1: Alpha-adaptin ear subdomain-like first appeared (with stable ids) in SCOP 1.55, called Family b.1.10.1: Clathrin adaptor appendage domain
  
• Family b.1.10.1: Alpha-adaptin ear subdomain-like appears in SCOPe 2.05
  
• Family b.1.10.1: Alpha-adaptin ear subdomain-like appears in SCOPe 2.07
  
• Family b.1.10.1: Alpha-adaptin ear subdomain-like appears in the current release, SCOPe 2.08