Lineage for Family b.1.2.1: Fibronectin type III

  1. Root: SCOPe 2.05
  2. 1755445Class b: All beta proteins [48724] (176 folds)
  3. 1755446Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1767525Superfamily b.1.2: Fibronectin type III [49265] (2 families) (S)
  5. 1767526Family b.1.2.1: Fibronectin type III [49266] (45 proteins)
    Pfam PF00041

Proteins:

  1. 1767527Brother of CDO precursor (BOC) [141037] (1 species)
  2. 1767531Ciliary neurotrophic factor receptor alpha [110060] (1 species)
  3. 1767534Common beta-chain in the GM-CSF, IL-3 and IL-5 receptors [49289] (1 species)
    duplication: consists of four similar domains; dimerizes by swapping the C-terminal strands of domains 1 and 3
  4. 1767554Contactin 3 (KIAA1496) [117055] (1 species)
  5. 1767557Cytokine receptor common gamma chain [141041] (1 species)
  6. 1767569Cytokine receptor gp130 cytokine-binding domains [49295] (1 species)
  7. 1767586Down syndrome cell adhesion molecule-like protein 1, DSCAML1 [141055] (1 species)
  8. 1767589Ephrin type-A receptor 1 [141063] (1 species)
  9. 1767592Ephrin type-A receptor 8 [141039] (1 species)
  10. 1767595Ephrin type-B receptor 1 [141035] (1 species)
  11. 1767598Erythropoietin (EPO) receptor [49282] (1 species)
  12. 1767626Extracellular region of human tissue factor [49267] (2 species)
    tandem of fibronectin type III domains
    1. 1767627Species Human (Homo sapiens) [TaxId:9606] [49268] (34 PDB entries)
      Uniprot P13726 33-242
    2. 1767699Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [49269] (1 PDB entry)
  13. 1767704Fibronectin type 3 and ankyrin repeat domains 1 protein, FANK1 [117053] (1 species)
  14. 1767707Fibronectin type III domain from chitinase A1. [81975] (1 species)
  15. 1767710Fibronectin type-III domain containing protein 3a, FNDC3A (KIAA0970) [117057] (1 species)
  16. 1767718Fibronectin, different Fn3 modules [49270] (3 species)
    1. 1767719Species Escherichia coli K-12 [TaxId:83333] [158899] (1 PDB entry)
    2. 1767721Species Human (Homo sapiens) [TaxId:9606] [49271] (9 PDB entries)
    3. 1767736Species Mouse (Mus musculus) [TaxId:10090] [49272] (2 PDB entries)
  17. 1767741Granulocyte colony-stimulating factor (GC-SF) receptor [49291] (2 species)
    1. 1767742Species Human (Homo sapiens) [TaxId:9606] [141034] (1 PDB entry)
      Uniprot Q99062 120-226! Uniprot Q99062 227-331
    2. 1767745Species Mouse (Mus musculus) [TaxId:10090] [49292] (4 PDB entries)
  18. 1767760Growth hormone receptor [49280] (1 species)
  19. 1767784Hedgehog receptor iHog [141061] (1 species)
    Cg9211-PA
  20. 1767798Host cell factor 2, HCF-2 [117051] (1 species)
  21. 1767801Insulin receptor [158901] (1 species)
  22. 1767806Integrin beta-4 subunit [49278] (1 species)
  23. 1767817Interferon-alpha/beta receptor beta chain [89199] (1 species)
  24. 1767827Interferon-gamma receptor alpha chain [49293] (1 species)
  25. 1767840Interleukin-10 receptor 1, IL-10R1 [63670] (1 species)
  26. 1767854Interleukin-2 receptor beta chain [141047] (1 species)
  27. 1767864Interleukin-4 receptor alpha chain [49287] (1 species)
  28. 1767868Interleukin-6 receptor alpha chain, domains 2 and 3 [81977] (1 species)
  29. 1767874KIAA0343 protein [101531] (1 species)
  30. 1767878KIAA1355 [110058] (1 species)
  31. 1767881KIAA1568 protein [101529] (1 species)
  32. 1767885Myosin binding protein C, fast-type [141057] (1 species)
  33. 1767888Neogenin [141053] (1 species)
  34. 1767896Neural cell adhesion molecule 1, NCAM [89197] (2 species)
    1. 1767897Species Human (Homo sapiens) [TaxId:9606] [141033] (4 PDB entries)
      Uniprot P13592 498-598
    2. 1767918Species Norway rat (Rattus norvegicus) [TaxId:10116] [89198] (1 PDB entry)
  35. 1767920Neuroglian, two amino proximal Fn3 repeats [49276] (1 species)
    tandem of fibronectin type III domains
  36. 1767924Prolactin receptor [49284] (2 species)
    1. Species Human (Homo sapiens) [TaxId:9606] [49285] (1 PDB entry)
    2. 1767928Species Norway rat (Rattus norvegicus) [TaxId:10116] [49286] (1 PDB entry)
  37. 1767933Receptor-type tyrosine-protein phosphatase delta, PTPRD [141049] (1 species)
  38. 1767937Receptor-type tyrosine-protein phosphatase F, PTPRF [141059] (1 species)
  39. 1767940Rim binding protein 2 [141043] (1 species)
  40. 1767943Sidekick 2 [141051] (1 species)
  41. 1767949Tenascin [49273] (3 species)
    1. 1767950Species Chicken (Gallus gallus) [TaxId:9031] [49274] (1 PDB entry)
    2. 1767955Species Human (Homo sapiens) [TaxId:9606] [49275] (1 PDB entry)
    3. 1767957Species Norway rat (Rattus norvegicus) [TaxId:10116] [110057] (1 PDB entry)
      Uniprot Q05546 502-770
  42. 1767961Tenascin-X [141045] (1 species)
  43. 1767966The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 [63672] (1 species)
  44. 1767982Type I titin module [49297] (1 species)
  45. 1767985automated matches [190888] (1 species)
    not a true protein

More info for Family b.1.2.1: Fibronectin type III

Timeline for Family b.1.2.1: Fibronectin type III: