Lineage for Family b.1.2.1: Fibronectin type III

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 787437Superfamily b.1.2: Fibronectin type III [49265] (1 family) (S)
  5. 787438Family b.1.2.1: Fibronectin type III [49266] (44 proteins)
    Pfam PF00041

Proteins:

  1. 787439Brother of CDO precursor (BOC) [141037] (1 species)
  2. 787443Ciliary neurotrophic factor receptor alpha [110060] (1 species)
  3. 787446Common beta-chain in the GM-CSF, IL-3 and IL-5 receptors [49289] (1 species)
    duplication: consists of four similar domains; dimerizes by swapping the C-terminal strands of domains 1 and 3
  4. 787466Contactin 3 (KIAA1496) [117055] (1 species)
  5. 787469Cytokine receptor common gamma chain [141041] (1 species)
  6. 787479Cytokine receptor gp130 cytokine-binding domains [49295] (1 species)
  7. 787496Down syndrome cell adhesion molecule-like protein 1, DSCAML1 [141055] (1 species)
  8. 787499Ephrin type-A receptor 1 [141063] (1 species)
  9. 787502Ephrin type-A receptor 8 [141039] (1 species)
  10. 787505Ephrin type-B receptor 1 [141035] (1 species)
  11. 787508Erythropoietin (EPO) receptor [49282] (2 species)
    1. 787509Species Escherichia coli [TaxId:562] [158900] (1 PDB entry)
    2. 787516Species Human (Homo sapiens) [TaxId:9606] [49283] (5 PDB entries)
  12. 787537Extracellular region of human tissue factor [49267] (2 species)
    tandem of fibronectin type III domains
    1. 787538Species Human (Homo sapiens) [TaxId:9606] [49268] (12 PDB entries)
      Uniprot P13726 33-242
    2. 787566Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [49269] (18 PDB entries)
  13. 787605Fibronectin type 3 and ankyrin repeat domains 1 protein, FANK1 [117053] (1 species)
  14. 787608Fibronectin type III domain from chitinase A1. [81975] (1 species)
  15. 787611Fibronectin type-III domain containing protein 3a, FNDC3A (KIAA0970) [117057] (1 species)
  16. 787619Fibronectin, different Fn3 modules [49270] (3 species)
    1. 787620Species Escherichia coli K12 (Escherichia coli K-12) [TaxId:83333] [158899] (1 PDB entry)
    2. 787622Species Human (Homo sapiens) [TaxId:9606] [49271] (9 PDB entries)
    3. 787637Species Mouse (Mus musculus) [TaxId:10090] [49272] (2 PDB entries)
  17. 787642Granulocyte colony-stimulating factor (GC-SF) receptor [49291] (2 species)
    1. 787643Species Human (Homo sapiens) [TaxId:9606] [141034] (1 PDB entry)
      Uniprot Q99062 120-226! Uniprot Q99062 227-331
    2. 787646Species Mouse (Mus musculus) [TaxId:10090] [49292] (4 PDB entries)
  18. 787661Growth hormone receptor [49280] (1 species)
  19. 787689Hedgehog receptor iHog [141061] (1 species)
    Cg9211-PA
  20. 787703Host cell factor 2, HCF-2 [117051] (1 species)
  21. 787706Insulin receptor [158901] (1 species)
  22. 787711Integrin beta-4 subunit [49278] (1 species)
  23. 787717Interferon-alpha/beta receptor beta chain [89199] (1 species)
  24. 787725Interferon-gamma receptor alpha chain [49293] (1 species)
  25. 787738Interleukin-10 receptor 1, IL-10R1 [63670] (1 species)
  26. 787752Interleukin-2 receptor beta chain [141047] (1 species)
  27. 787760Interleukin-4 receptor alpha chain [49287] (1 species)
  28. 787764Interleukin-6 receptor alpha chain, domains 2 and 3 [81977] (1 species)
  29. 787771KIAA0343 protein [101531] (1 species)
  30. 787775KIAA1355 [110058] (1 species)
  31. 787778KIAA1568 protein [101529] (1 species)
  32. 787782Myosin binding protein C, fast-type [141057] (1 species)
  33. 787785Neogenin [141053] (1 species)
  34. 787793Neural cell adhesion molecule 1, NCAM [89197] (2 species)
    1. 787794Species Human (Homo sapiens) [TaxId:9606] [141033] (3 PDB entries)
      Uniprot P13592 498-598
    2. 787812Species Rat (Rattus norvegicus) [TaxId:10116] [89198] (1 PDB entry)
  35. 787814Neuroglian, two amino proximal Fn3 repeats [49276] (1 species)
    tandem of fibronectin type III domains
  36. 787818Prolactin receptor [49284] (2 species)
    1. 787819Species Human (Homo sapiens) [TaxId:9606] [49285] (2 PDB entries)
    2. 787824Species Rat (Rattus norvegicus) [TaxId:10116] [49286] (1 PDB entry)
  37. 787829Receptor-type tyrosine-protein phosphatase delta, PTPRD [141049] (1 species)
  38. 787832Receptor-type tyrosine-protein phosphatase F, PTPRF [141059] (1 species)
  39. 787835Rim binding protein 2 [141043] (1 species)
  40. 787838Sidekick 2 [141051] (1 species)
  41. 787844Tenascin [49273] (3 species)
    1. 787845Species Chicken (Gallus gallus) [TaxId:9031] [49274] (1 PDB entry)
    2. 787850Species Human (Homo sapiens) [TaxId:9606] [49275] (1 PDB entry)
    3. 787852Species Rat (Rattus norvegicus) [TaxId:10116] [110057] (1 PDB entry)
      Uniprot Q05546 502-770
  42. 787856Tenascin-X [141045] (1 species)
  43. 787861The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 [63672] (1 species)
  44. 787877Type I titin module [49297] (1 species)

More info for Family b.1.2.1: Fibronectin type III

Timeline for Family b.1.2.1: Fibronectin type III: