Lineage for Family b.1.2.1: Fibronectin type III

  1. Root: SCOP 1.69
  2. 450777Class b: All beta proteins [48724] (144 folds)
  3. 450778Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 454980Superfamily b.1.2: Fibronectin type III [49265] (1 family) (S)
  5. 454981Family b.1.2.1: Fibronectin type III [49266] (24 proteins)

Proteins:

  1. 454982Ciliary neurotrophic factor receptor alpha [110060] (1 species)
  2. 454985Common beta-chain in the GM-CSF, IL-3 and IL-5 receptors [49289] (1 species)
    duplication: consists of four similar domains; dimerizes by swapping the C-terminal strands of domains 1 and 3
  3. 454997Cytokine receptor gp130 cytokine-binding domains [49295] (1 species)
  4. 455014Erythropoietin (EPO) receptor [49282] (1 species)
  5. 455036Extracellular region of human tissue factor [49267] (2 species)
    tandem of fibronectin type III domains
    1. 455037Species Human (Homo sapiens) [TaxId:9606] [49268] (10 PDB entries)
    2. 455062Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [49269] (1 PDB entry)
  6. 455067Fibronectin type III domain from chitinase A1. [81975] (1 species)
  7. 455070Fibronectin, different Fn3 modules [49270] (2 species)
    1. 455071Species Human (Homo sapiens) [TaxId:9606] [49271] (9 PDB entries)
    2. 455086Species Mouse (Mus musculus) [TaxId:10090] [49272] (2 PDB entries)
  8. 455091Granulocyte colony-stimulating factor (GC-SF) receptor [49291] (1 species)
  9. 455107Growth hormone receptor [49280] (1 species)
  10. 455131Integrin beta-4 subunit [49278] (1 species)
  11. 455137Interferon-alpha/beta receptor beta chain [89199] (1 species)
  12. 455143Interferon-gamma receptor alpha chain [49293] (1 species)
  13. 455156Interleukin-10 receptor 1, IL-10R1 [63670] (1 species)
  14. 455164Interleukin-4 receptor alpha chain [49287] (1 species)
  15. 455168Interleukin-6 receptor alpha chain, domains 2 and 3 [81977] (1 species)
  16. 455174KIAA0343 protein [101531] (1 species)
  17. 455178KIAA1355 [110058] (1 species)
  18. 455181KIAA1568 protein [101529] (1 species)
  19. 455185Neural cell adhesion molecule 1, NCAM [89197] (1 species)
  20. 455188Neuroglian, two amino proximal Fn3 repeats [49276] (1 species)
    tandem of fibronectin type III domains
  21. 455192Prolactin receptor [49284] (2 species)
    1. 455193Species Human (Homo sapiens) [TaxId:9606] [49285] (1 PDB entry)
    2. 455196Species Rat (Rattus norvegicus) [TaxId:10116] [49286] (1 PDB entry)
  22. 455201Tenascin [49273] (3 species)
    1. 455202Species Chicken (Gallus gallus) [TaxId:9031] [49274] (1 PDB entry)
    2. 455207Species Human (Homo sapiens) [TaxId:9606] [49275] (1 PDB entry)
    3. 455209Species Rat (Rattus norvegicus) [TaxId:10116] [110057] (1 PDB entry)
  23. 455213The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 [63672] (1 species)
  24. 455219Type I titin module [49297] (1 species)

More info for Family b.1.2.1: Fibronectin type III

Timeline for Family b.1.2.1: Fibronectin type III: