SCOP 1.69: Family a.138.1.1: Cytochrome c3-like

Lineage for Family a.138.1.1: Cytochrome c3-like

1. Root: SCOP 1.69

2. Class a: All alpha proteins [46456] (218 folds)

3. Fold a.138: Multiheme cytochromes [48694] (1 superfamily)
   variable number of helices and little beta structure; not a true fold

4. Superfamily a.138.1: Multiheme cytochromes [48695] (3 families)
   duplication: contains multiple CxxCH motifs

5. Family a.138.1.1: Cytochrome c3-like [48696] (4 proteins)

Proteins:

1. 16-heme cytochrome c HmcA [81940] (1 species)
   tandem repeat of four cytochrome c3-like domains

   • Species Desulfovibrio vulgaris [TaxId:881] [81941] (2 PDB entries)

2. Cytochrome c3 [48697] (6 species)
   contains four heme groups

   1. Species Desulfomicrobium norvegicum [TaxId:52561] [48702] (1 PDB entry)
      synonym: Desulfovibrio desulfuricans Norway

   2. Species Desulfovibrio africanus [TaxId:873] [48701] (2 PDB entries)

   3. Species Desulfovibrio desulfuricans, different strains [TaxId:876] [48698] (6 PDB entries)

   4. Species Desulfovibrio gigas [TaxId:879] [48700] (3 PDB entries)

   5. Species Desulfovibrio gigas, di-tetraheme cytochrome c3 [TaxId:879] [74804] (1 PDB entry)
      disulfide-crosslinked dimer

   6. Species Desulfovibrio vulgaris [TaxId:881] [48699] (8 PDB entries)

3. Cytochrome c7 (cytochrome c551.5, PpcA) [48703] (3 species)
   contains three heme groups; deletion of one of Cyt c3 heme-binding sites

   1. Species Desulfuromonas acetoxidans [TaxId:891] [48704] (8 PDB entries)

   2. Species Geobacter sulfurreducens [101502] (1 PDB entry)

   3. Species Geobacter sulfurreducens [110039] (1 PDB entry)

4. Nine-heme cytochrome c [48705] (2 species)
   tandem repeat of two cytochrome c3-like domains with additional heme-binding site in the domain interface

   1. Species Desulfovibrio desulfuricans, ATCC 27774 [TaxId:876] [48706] (3 PDB entries)

   2. Species Desulfovibrio desulfuricans, ATCC 29577 [TaxId:876] [63634] (1 PDB entry)

More info for Family a.138.1.1: Cytochrome c3-like

Timeline for Family a.138.1.1: Cytochrome c3-like:

• Family a.138.1.1: Cytochrome c3-like first appeared (with stable ids) in SCOP 1.55
  
• Family a.138.1.1: Cytochrome c3-like appears in SCOP 1.67
  
• Family a.138.1.1: Cytochrome c3-like appears in SCOP 1.71
  
• Family a.138.1.1: Cytochrome c3-like appears in the current release, SCOPe 2.08