Lineage for Protein: Phospholipase A2

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2338840Fold a.133: Phospholipase A2, PLA2 [48618] (1 superfamily)
    common core: 2 helices, disulfide-linked, and a calcium-binding loop
  4. 2338841Superfamily a.133.1: Phospholipase A2, PLA2 [48619] (4 families) (S)
  5. 2338846Family a.133.1.2: Vertebrate phospholipase A2 [48623] (3 protein domains)
    automatically mapped to Pfam PF00068
  6. 2338847Protein Phospholipase A2 [48637] (5 species)

Species:

  1. 2338848Cow (Bos taurus), pancreas [TaxId:9913] [48639] (32 PDB entries)
    Uniprot P00593
    1. Domain for 1bp2:
    2. Domain for 1bpq:
    3. Domain for 1bvm:
    4. Domain for 1c74:
    5. Domain for 1ceh:
    6. Domain for 1fdk:
    7. Domain for 1g4i:
    8. Domain for 1gh4:
    9. Domain for 1irb:
    10. Domain for 1kvw:
    11. Domain for 1kvx:
    12. Domain for 1kvy:
    13. Domain for 1mks:
    14. Domain for 1mkt:
    15. Domain for 1mku:
    16. Domain for 1mkv:
    17. Domain for 1o2e:
    18. Domain for 1o3w:
    19. Domain for 1une:
    20. Domain for 1vkq:
    21. Domain for 1vl9:
    22. Domain for 2b96:
    23. Domain for 2bax:
    24. Domain for 2bch:
    25. Domains for 2bd1:
      1. 2338876Domain d2bd1a_: 2bd1 A: [163044]
        automated match to d1gh4a_
        complexed with ca, mpd; mutant
      2. 2338877Domain d2bd1b_: 2bd1 B: [163045]
        automated match to d1gh4a_
        complexed with ca, mpd; mutant
    26. Domain for 2bp2:
    27. Domain for 2bpp:
    28. Domain for 2zp3:
    29. Domain for 2zp4:
    30. Domain for 2zp5:
    31. Domain for 3bp2:
    32. Domain for 4bp2:
  2. 2338882Human (Homo sapiens) [TaxId:9606] [188854] (1 PDB entry)
  3. 2338884Human (Homo sapiens), SPLA2 [TaxId:9606] [74797] (5 PDB entries)
    group X secretory phospholipase A2
    1. Domains for 1le6:
      1. 2338885Domain d1le6a_: 1le6 A: [73862]
        complexed with ca, mpd
      2. 2338886Domain d1le6b_: 1le6 B: [73863]
        complexed with ca, mpd
      3. 2338887Domain d1le6c_: 1le6 C: [73864]
        complexed with ca, mpd
    2. Domains for 1le7:
      1. 2338888Domain d1le7a_: 1le7 A: [73865]
        complexed with ca, mpd
      2. 2338889Domain d1le7b_: 1le7 B: [73866]
        complexed with ca, mpd
    3. Domains for 5g3m:
      1. 2338890Domain d5g3ma_: 5g3m A: [322877]
        automated match to d1le6a_
        complexed with 9jh, ca, dms, peg
      2. 2338891Domain d5g3mb_: 5g3m B: [322635]
        automated match to d1le6a_
        complexed with 9jh, ca, dms, peg
    4. Domains for 5ow8:
      1. 3055497Domain d5ow8b_: 5ow8 B: [355559]
        automated match to d1le6a_
        complexed with ayn, ca, cl, dms, peg
      2. 3055505Domain d5ow8a_: 5ow8 A: [355567]
        automated match to d1le6a_
        complexed with ayn, ca, cl, dms, peg
    5. Domains for 6g5j:
      1. 3056976Domain d6g5ja_: 6g5j A: [357038]
        automated match to d1le6a_
        complexed with ca, dms, em8, peg
      2. 3056981Domain d6g5jb_: 6g5j B: [357043]
        automated match to d1le6a_
        complexed with ca, dms, em8, peg
  4. 2338892Human (Homo sapiens), synovial fluid [TaxId:9606] [48638] (16 PDB entries)
    1. Domains for 1ayp:
      1. 2338916Domain d1aypa_: 1ayp A: [19575]
        complexed with ca, inb
      2. 2338917Domain d1aypb_: 1ayp B: [19576]
        complexed with ca, inb
      3. 2338918Domain d1aypc_: 1ayp C: [19577]
        complexed with ca, inb
      4. 2338919Domain d1aypd_: 1ayp D: [19578]
        complexed with ca, inb
      5. 2338920Domain d1aype_: 1ayp E: [19579]
        complexed with ca, inb
      6. 2338921Domain d1aypf_: 1ayp F: [19580]
        complexed with ca, inb
    2. Domain for 1bbc:
    3. Domain for 1db4:
    4. Domain for 1db5:
    5. Domain for 1dcy:
    6. Domains for 1j1a:
      1. 2338913Domain d1j1aa_: 1j1a A: [83961]
        complexed with bhp, ca
      2. 2338914Domain d1j1ab_: 1j1a B: [83962]
        complexed with bhp, ca
    7. Domain for 1kqu:
    8. Domains for 1kvo:
      1. 2338899Domain d1kvoa_: 1kvo A: [19564]
        complexed with ca, oap
      2. 2338900Domain d1kvob_: 1kvo B: [19565]
        complexed with ca, oap
      3. 2338901Domain d1kvoc_: 1kvo C: [19566]
        complexed with ca, oap
      4. 2338902Domain d1kvod_: 1kvo D: [19567]
        complexed with ca, oap
      5. 2338903Domain d1kvoe_: 1kvo E: [19568]
        complexed with ca, oap
      6. 2338904Domain d1kvof_: 1kvo F: [19569]
        complexed with ca, oap
    9. Domains for 1n28:
      1. 2338895Domain d1n28a_: 1n28 A: [91550]
        complexed with ca; mutant
      2. 2338896Domain d1n28b_: 1n28 B: [91551]
        complexed with ca; mutant
    10. Domain for 1n29:
    11. Domain for 1pod:
    12. Domains for 1poe:
      1. 2338910Domain d1poea_: 1poe A: [19571]
        complexed with ca, gel
      2. 2338911Domain d1poeb_: 1poe B: [19572]
        complexed with ca, gel
    13. Domain for 3u8b:
    14. Domains for 3u8d:
      1. 2338897Domain d3u8da_: 3u8d A: [192821]
        automated match to d1kvoa_
        complexed with ca, cl, u8d
      2. 2338898Domain d3u8db_: 3u8d B: [192515]
        automated match to d1kvoa_
        complexed with ca, cl, u8d
    15. Domains for 3u8h:
      1. 2338906Domain d3u8ha_: 3u8h A: [192820]
        automated match to d1kvoa_
        complexed with bhp, ca, cl
      2. 2338907Domain d3u8hb_: 3u8h B: [192514]
        automated match to d1kvoa_
        complexed with bhp, ca, cl
    16. Domains for 3u8i:
      1. 2338893Domain d3u8ia_: 3u8i A: [194471]
        automated match to d1kvoa_
        complexed with ca, cl, na
      2. 2338894Domain d3u8ib_: 3u8i B: [194470]
        automated match to d1kvoa_
        complexed with ca, cl, na
  5. 2338925Pig (Sus scrofa), pancreas [TaxId:9823] [48640] (23 PDB entries)
    1. Domains for 1fx9:
      1. 2338933Domain d1fx9a_: 1fx9 A: [60100]
        complexed with ca, mji, so4
      2. 2338934Domain d1fx9b_: 1fx9 B: [60101]
        complexed with ca, mji, so4
    2. Domains for 1fxf:
      1. 2338931Domain d1fxfa_: 1fxf A: [60102]
        complexed with ca, mji, po4
      2. 2338932Domain d1fxfb_: 1fxf B: [60103]
        complexed with ca, mji, po4
    3. Domains for 1hn4:
      1. 2338926Domain d1hn4a_: 1hn4 A: [65893]
        complexed with ca, mji, so4
      2. 2338927Domain d1hn4b_: 1hn4 B: [65894]
        complexed with ca, mji, so4
    4. Domains for 1l8s:
      1. 2338928Domain d1l8sa_: 1l8s A: [77811]
        complexed with act, ca, lpe, na, po4
      2. 2338929Domain d1l8sb_: 1l8s B: [77812]
        complexed with act, ca, lpe, na, po4
    5. Domain for 1p2p:
    6. Domain for 1pir:
    7. Domain for 1pis:
    8. Domain for 1sfv:
    9. Domain for 1sfw:
    10. Domains for 1y6o:
      1. 2338935Domain d1y6oa_: 1y6o A: [162160]
        automated match to d1hn4b_
        complexed with ca, mji, po4
      2. 2338936Domain d1y6ob_: 1y6o B: [162161]
        automated match to d1hn4b_
        complexed with ca, mji, po4
    11. Domains for 1y6p:
      1. 2338940Domain d1y6pa_: 1y6p A: [162162]
        automated match to d1hn4b_
        complexed with ca, cl
      2. 2338941Domain d1y6pb_: 1y6p B: [162163]
        automated match to d1hn4b_
        complexed with ca, cl
    12. Domain for 2azz:
    13. Domain for 2b00:
    14. Domain for 2b01:
    15. Domain for 2b03:
    16. Domain for 2b04:
    17. Domains for 2phi:
      1. 2338937Domain d2phia_: 2phi A: [19602]
        complexed with ca; mutant
      2. 2338938Domain d2phib_: 2phi B: [19603]
        complexed with ca; mutant
    18. Domain for 3l69:
    19. Domains for 3p2p:
      1. 2338945Domain d3p2pa_: 3p2p A: [19607]
        complexed with ca
      2. 2338946Domain d3p2pb_: 3p2p B: [19608]
        complexed with ca
    20. Domain for 3tt5:
    21. Domain for 4o1y:
    22. Domain for 4p2p:
    23. Domains for 5p2p:
      1. 2338949Domain d5p2pa_: 5p2p A: [19605]
        complexed with ca, dhg
      2. 2338950Domain d5p2pb_: 5p2p B: [19606]
        complexed with ca, dhg

More info for Protein Phospholipase A2 from a.133.1.2: Vertebrate phospholipase A2

Timeline for Protein Phospholipase A2 from a.133.1.2: Vertebrate phospholipase A2: