Lineage for Family a.133.1.2: Vertebrate phospholipase A2

  1. Root: SCOP 1.73
  2. 631650Class a: All alpha proteins [46456] (258 folds)
  3. 649171Fold a.133: Phospholipase A2, PLA2 [48618] (1 superfamily)
    common core: 2 helices, disulfide-linked, and a calcium-binding loop
  4. 649172Superfamily a.133.1: Phospholipase A2, PLA2 [48619] (3 families) (S)
  5. 649177Family a.133.1.2: Vertebrate phospholipase A2 [48623] (2 proteins)

Proteins:

  1. 649178Phospholipase A2 [48637] (4 species)
    1. 649179Species Cow (Bos taurus), pancreas [TaxId:9913] [48639] (26 PDB entries)
    2. 649206Species Human (Homo sapiens), SPLA2 [TaxId:9606] [74797] (2 PDB entries)
      group X secretory phospholipase A2
    3. 649212Species Human (Homo sapiens), synovial fluid [TaxId:9606] [48638] (12 PDB entries)
    4. 649238Species Pig (Sus scrofa), pancreas [TaxId:9823] [48640] (19 PDB entries)
  2. 649265Snake phospholipase A2 [48624] (35 species)
    1. 649266Species Bothrops pirajai, Piratoxin-II (PRTX-II) [TaxId:113192] [48633] (1 PDB entry)
    2. 649269Species Broad-banded copperhead (Agkistrodon contortrix laticinctus) [TaxId:37195] [101483] (3 PDB entries)
    3. 649273Species Cerrophidion godmani, formerly Bothrops godmani [TaxId:44722] [48645] (1 PDB entry)
      Monomeric Lys-49 phospholipase A2 homologue
    4. 649275Species Eastern cottonmouth snake (Agkistrodon piscivorus piscivorus) [TaxId:8716] [48629] (2 PDB entries)
    5. 649279Species Hundred-pace snake (Agkistrodon acutus) [TaxId:36307] [74796] (2 PDB entries)
      monomeric Lys-49 phospholipase A2 homologue
    6. 649282Species Indian cobra (Naja naja sagittifera), acidic isoform 1 [TaxId:195058] [89168] (1 PDB entry)
    7. 649284Species Indian cobra (Naja naja sagittifera), calcium-free isoform 5 [TaxId:195058] [89172] (2 PDB entries)
    8. 649287Species Indian cobra (Naja naja sagittifera), isoform 2 [TaxId:195058] [89169] (2 PDB entries)
      heterodimer of two different isoforms
    9. 649290Species Indian cobra (Naja naja sagittifera), isoform 3 [TaxId:195058] [89170] (2 PDB entries)
      heterodimer of two different isoforms
    10. 649293Species Indian cobra (Naja naja sagittifera), isoform 4 [TaxId:195058] [89171] (7 PDB entries)
    11. 649301Species Indian cobra (Naja naja) [TaxId:35670] [48626] (4 PDB entries)
    12. 649311Species Indian cobra (Naja naja), a C49 isoform 2 [TaxId:35670] [89166] (1 PDB entry)
    13. 649313Species Indian cobra (Naja naja), isoform 3 [TaxId:35670] [89167] (1 PDB entry)
    14. 649315Species Indian krait (Bungarus caeruleus), different isoforms [TaxId:132961] [48636] (8 PDB entries)
    15. 649328Species Jararacussu (Bothrops jararacussu) [TaxId:8726] [101487] (4 PDB entries)
    16. 649334Species King cobra (Ophiophagus hannah) [TaxId:8665] [81939] (1 PDB entry)
    17. 649338Species King cobra (Ophiophagus hannah), an acidic isoform [TaxId:8665] [101482] (1 PDB entry)
    18. 649345Species Mainland tiger snake (Notechis scutatus scutatus), notechis II-5 [TaxId:8663] [48632] (1 PDB entry)
      neurotoxic phospholipase a2
    19. 649348Species Mainland tiger snake (Notechis scutatus scutatus), notexin [TaxId:8663] [48631] (1 PDB entry)
      presynaptic neurotoxic phospholipase A2
    20. 649350Species Many-banded krait (Bungarus multicinctus), beta2-bungarotoxin [TaxId:8616] [48642] (1 PDB entry)
    21. 649352Species Neuwied's lancehead (Bothrops neuwiedi pauloensis), different isoforms [TaxId:95649] [110032] (2 PDB entries)
    22. 649357Species Russell's viper (Vipera russelli) [TaxId:8707] [48634] (1 PDB entry)
      anticoagulant class II phospholipase A2
    23. 649359Species Sand viper (Vipera ammodytes meridionalis), vipoxin catalytic subunit [TaxId:8704] [88518] (2 PDB entries)
    24. 649362Species Sand viper (Vipera ammodytes meridionalis), vipoxin inhibitor [TaxId:8704] [88517] (5 PDB entries)
    25. 649372Species Saw-scaled viper (Echis carinatus) [TaxId:40353] [101486] (1 PDB entry)
    26. 649374Species Siamese russell's viper (Daboia russelli siamensis), RV4 catalytic subunit [TaxId:343250] [101485] (1 PDB entry)
    27. 649379Species Siamese russell's viper (Daboia russelli siamensis), RV7 inhibitory subunit [TaxId:343250] [101484] (1 PDB entry)
    28. 649384Species Small-eye snake (Micropechis ikaheka), different isoforms [TaxId:66188] [110033] (2 PDB entries)
    29. 649393Species Snake (Agkistrodon halys) [TaxId:8714] [48628] (9 PDB entries)
    30. 649422Species Snake (Bothrops pirajai), piratoxin III [TaxId:113192] [69123] (1 PDB entry)
    31. 649425Species Snake (Daboia russellii pulchella), different isoforms [TaxId:97228] [48630] (47 PDB entries)
    32. 649483Species Taiwan cobra (Naja naja atra) [TaxId:8656] [48625] (2 PDB entries)
    33. 649487Species Terciopelo (Bothrops asper), myotoxin I [TaxId:8722] [48644] (2 PDB entries)
    34. 649492Species Viper (Deinagkistrodon acutus) [TaxId:36307] [69122] (1 PDB entry)
    35. 649495Species Western diamondback rattlesnake (Crotalus atrox) [TaxId:8730] [48627] (1 PDB entry)

More info for Family a.133.1.2: Vertebrate phospholipase A2

Timeline for Family a.133.1.2: Vertebrate phospholipase A2: