SCOPe 2.08: Protein: Heme oxygenase-1 (HO-1)

Lineage for Protein: Heme oxygenase-1 (HO-1)

Root: SCOPe 2.08
Class a: All alpha proteins [46456] (290 folds)
Fold a.132: Heme oxygenase-like [48612] (1 superfamily)
multihelical; bundle
Superfamily a.132.1: Heme oxygenase-like [48613] (5 families)
duplication: contains two structural repeats of 3-helical motif
Family a.132.1.1: Eukaryotic type heme oxygenase [48614] (4 proteins)
automatically mapped to Pfam PF01126
Protein Heme oxygenase-1 (HO-1) [48615] (3 species)

Species:

Human (Homo sapiens) [TaxId:9606] [48616] (26 PDB entries)
Uniprot P09601
1. Domains for 1n3u:
  1. Domain d1n3ua_: 1n3u A: [79973]
    complexed with cl, hem
  2. Domain d1n3ub_: 1n3u B: [79974]
    complexed with cl, hem
2. Domains for 1n45:
  1. Domain d1n45a_: 1n45 A: [79981]
    complexed with hem, so4
  2. Domain d1n45b_: 1n45 B: [79982]
    complexed with hem, so4
3. Domains for 1ni6:
  1. Domain d1ni6a_: 1ni6 A: [85734]
    heme-free structure
    complexed with cl
  2. Domain d1ni6b_: 1ni6 B: [85735]
    heme-free structure
    complexed with cl
  3. Domain d1ni6c_: 1ni6 C: [85736]
    heme-free structure
    complexed with cl
  4. Domain d1ni6d_: 1ni6 D: [85737]
    heme-free structure
    complexed with cl
4. Domains for 1oyk:
  1. Domain d1oyka_: 1oyk A: [93730]
    complexed with hem; mutant
  2. Domain d1oykb_: 1oyk B: [93731]
    complexed with hem; mutant
5. Domains for 1oyl:
  1. Domain d1oyla_: 1oyl A: [93732]
    complexed with hem; mutant
  2. Domain d1oylb_: 1oyl B: [93733]
    complexed with hem; mutant
6. Domains for 1oze:
  1. Domain d1ozea_: 1oze A: [93819]
    complexed with hem; mutant
  2. Domain d1ozeb_: 1oze B: [93820]
    complexed with hem; mutant
7. Domains for 1ozl:
  1. Domain d1ozla_: 1ozl A: [93848]
    complexed with hem, no; mutant
  2. Domain d1ozlb_: 1ozl B: [93849]
    complexed with hem, no; mutant
8. Domains for 1ozr:
  1. Domain d1ozra_: 1ozr A: [93855]
    complexed with hem; mutant
  2. Domain d1ozrb_: 1ozr B: [93856]
    complexed with hem; mutant
9. Domains for 1ozw:
  1. Domain d1ozwa_: 1ozw A: [93858]
    complexed with hem, no; mutant
  2. Domain d1ozwb_: 1ozw B: [93859]
    complexed with hem, no; mutant
10. Domains for 1s13:
  1. Domain d1s13a_: 1s13 A: [105152]
    complexed with 2fh
  2. Domain d1s13b_: 1s13 B: [105153]
    complexed with 2fh
11. Domains for 1s8c:
  1. Domain d1s8ca_: 1s8c A: [105364]
    complexed with bla
  2. Domain d1s8cb_: 1s8c B: [105365]
    complexed with bla
  3. Domain d1s8cc_: 1s8c C: [105366]
    complexed with bla
  4. Domain d1s8cd_: 1s8c D: [105367]
    complexed with bla
12. Domains for 1t5p:
  1. Domain d1t5pa_: 1t5p A: [106463]
    complexed with 1fh
  2. Domain d1t5pb_: 1t5p B: [106464]
    complexed with 1fh
13. Domains for 1twn:
  1. Domain d1twna_: 1twn A: [119366]
    automated match to d1ni6c_
    complexed with ver
  2. Domain d1twnb_: 1twn B: [119367]
    automated match to d1ni6c_
    complexed with ver
14. Domains for 1twr:
  1. Domain d1twra_: 1twr A: [119369]
    automated match to d1ni6c_
    complexed with no, ver
  2. Domain d1twrb_: 1twr B: [119370]
    automated match to d1ni6c_
    complexed with no, ver
15. Domains for 1xjz:
  1. Domain d1xjza1: 1xjz A:10-223 [122049]
    complexed with hem; mutant
  2. Domain d1xjzb_: 1xjz B: [122050]
    automated match to d1ni6c_
    complexed with hem; mutant
16. Domains for 1xk0:
  1. Domain d1xk0a1: 1xk0 A:10-223 [122051]
    complexed with hem, no; mutant
  2. Domain d1xk0b_: 1xk0 B: [122052]
    automated match to d1ni6c_
    complexed with hem, no; mutant
17. Domains for 1xk1:
  1. Domain d1xk1a1: 1xk1 A:10-223 [122053]
    complexed with hem; mutant
  2. Domain d1xk1b_: 1xk1 B: [122054]
    automated match to d1ni6c_
    complexed with hem; mutant
18. Domains for 1xk2:
  1. Domain d1xk2a_: 1xk2 A: [115398]
    complexed with hem; mutant
  2. Domain d1xk2b_: 1xk2 B: [115399]
    complexed with hem; mutant
19. Domains for 1xk3:
  1. Domain d1xk3a_: 1xk3 A: [115400]
    complexed with hem, no; mutant
  2. Domain d1xk3b_: 1xk3 B: [115401]
    complexed with hem, no; mutant
20. Domains for 3czy:
  1. Domain d3czya_: 3czy A: [157159]
    automated match to d1ni6c_
    complexed with ad8, hem
  2. Domain d3czyb_: 3czy B: [157160]
    automated match to d1ni6c_
    complexed with ad8, hem
21. Domains for 3hok:
  1. Domain d3hoka_: 3hok A: [177735]
    automated match to d1ni6c_
    complexed with hem, q80
  2. Domain d3hokb_: 3hok B: [177736]
    automated match to d1ni6c_
    complexed with hem, q80
22. Domains for 3k4f:
  1. Domain d3k4fa_: 3k4f A: [179065]
    automated match to d1ni6c_
    complexed with hem, hez, q86, so4
  2. Domain d3k4fb_: 3k4f B: [179066]
    automated match to d1ni6c_
    complexed with hem, hez, q86, so4
23. Domains for 3tgm:
  1. Domain d3tgma_: 3tgm A: [185824]
    automated match to d1ni6c_
    complexed with 3tg, hem, hez
  2. Domain d3tgmb_: 3tgm B: [185825]
    automated match to d1ni6c_
    complexed with 3tg, hem, hez
24. Domains for 4wd4:
  1. Domain d4wd4a_: 4wd4 A: [276762]
    automated match to d1ix3a_
    complexed with epe, hem
  2. Domain d4wd4b_: 4wd4 B: [276763]
    automated match to d1ix3a_
    complexed with epe, hem
  3. Domain d4wd4c_: 4wd4 C: [276764]
    automated match to d1ix3a_
    complexed with epe, hem
  4. Domain d4wd4d_: 4wd4 D: [276765]
    automated match to d1ix3a_
    complexed with epe, hem
25. Domains for 5btq:
  1. Domain d5btqa_: 5btq A: [318130]
    automated match to d1ni6c_
    complexed with bla, so4
  2. Domain d5btqb_: 5btq B: [318150]
    automated match to d1ni6c_
    complexed with bla, so4
26. Domains for 6eha:
  1. Domain d6ehaa_: 6eha A: [358483]
    automated match to d1ix3a_
    complexed with b5b, hem
  2. Domain d6ehab_: 6eha B: [358488]
    automated match to d1ix3a_
    complexed with b5b, hem
Norway rat (Rattus norvegicus) [TaxId:10116] [48617] (25 PDB entries)
Uniprot P06762 11-222
1. Domain for 1dve:
  - Domain d1dvea_: 1dve A: [19512]
    complexed with hem
2. Domains for 1dvg:
  1. Domain d1dvga_: 1dvg A: [19510]
    complexed with hem
  2. Domain d1dvgb_: 1dvg B: [19511]
    complexed with hem
3. Domains for 1irm:
  1. Domain d1irma_: 1irm A: [71347]
  2. Domain d1irmb_: 1irm B: [71348]
  3. Domain d1irmc_: 1irm C: [71349]
4. Domain for 1ivj:
  - Domain d1ivja_: 1ivj A: [76844]
    complexed with azi, hem
5. Domain for 1ix3:
  - Domain d1ix3a_: 1ix3 A: [90714]
    complexed with cyn, hem
6. Domain for 1ix4:
  - Domain d1ix4a_: 1ix4 A: [90715]
    complexed with cmo, hem
7. Domain for 1j02:
  - Domain d1j02a_: 1j02 A: [90732]
    complexed with hem, no
8. Domain for 1j2c:
  - Domain d1j2ca_: 1j2c A: [90780]
    complexed with bla, fe
9. Domain for 1ubb:
  - Domain d1ubba_: 1ubb A: [99160]
    complexed with hem
10. Domain for 1ulx:
  - Domain d1ulxa_: 1ulx A: [107941]
    complexed with cmo, hem
11. Domain for 1vgi:
  - Domain d1vgia_: 1vgi A: [108622]
    complexed with fmt, hem, xe
12. Domain for 2dy5:
  - Domain d2dy5a_: 2dy5 A: [131890]
    automated match to d1dvea_
    complexed with 224, cl, hem
13. Domain for 2e7e:
  - Domain d2e7ea_: 2e7e A: [132063]
    automated match to d1j02a_
    complexed with cyn, hem
14. Domain for 2zvu:
  - Domain d2zvua_: 2zvu A: [207994]
    automated match to d1j02a_
    complexed with fmt, vea
15. Domain for 3i9t:
  - Domain d3i9ta_: 3i9t A: [211551]
    automated match to d1ix3a_
    complexed with dtv, hem
16. Domain for 3i9u:
  - Domain d3i9ua_: 3i9u A: [211552]
    automated match to d1ix3a_
    complexed with dtu, hem
17. Domain for 4g7l:
  - Domain d4g7la_: 4g7l A: [221748]
    automated match to d1ix3a_
    complexed with fmt, hem, oxy
18. Domain for 4g7p:
  - Domain d4g7pa_: 4g7p A: [221749]
    automated match to d1ix3a_
    complexed with cmo, fmt, hem
19. Domain for 4g7t:
  - Domain d4g7ta_: 4g7t A: [221756]
    automated match to d1j02a_
    complexed with cmo, fmt, hem
20. Domain for 4g7u:
  - Domain d4g7ua_: 4g7u A: [221757]
    automated match to d1ix3a_
    complexed with cmo, fmt, hem
21. Domain for 4g8p:
  - Domain d4g8pa_: 4g8p A: [221786]
    automated match to d1ix3a_
    complexed with cmo, fmt, hem
22. Domain for 4g8u:
  - Domain d4g8ua_: 4g8u A: [221797]
    automated match to d1ix3a_
    complexed with fmt, hem, oxy
23. Domain for 4g8w:
  - Domain d4g8wa_: 4g8w A: [221798]
    automated match to d1ix3a_
    complexed with fmt, hem, oxy
24. Domain for 4g98:
  - Domain d4g98a_: 4g98 A: [221805]
    automated match to d1j02a_
    complexed with cmo, fmt, hem
25. Domain for 4g99:
  - Domain d4g99a_: 4g99 A: [221806]
    automated match to d1j02a_
    complexed with cmo, fmt, hem
Synechocystis sp. [TaxId:1143] [117032] (1 PDB entry)
Uniprot P72849 2-223
- Domains for 1we1:
  1. Domain d1we1a_: 1we1 A: [114542]
    complexed with cl, hem, ipa, po4
  2. Domain d1we1b_: 1we1 B: [114543]
    complexed with cl, hem, ipa, po4
  3. Domain d1we1c_: 1we1 C: [114544]
    complexed with cl, hem, ipa, po4
  4. Domain d1we1d_: 1we1 D: [114545]
    complexed with cl, hem, ipa, po4

More info for Protein Heme oxygenase-1 (HO-1) from a.132.1.1: Eukaryotic type heme oxygenase

Timeline for Protein Heme oxygenase-1 (HO-1) from a.132.1.1: Eukaryotic type heme oxygenase:

Protein Heme oxygenase-1 (HO-1) from a.132.1.1: Eukaryotic type heme oxygenase first appeared (with stable ids) in SCOP 1.55, called Protein Heme oxygenase-1 (HO-1) from a.132.1.1: Heme oxygenase-1 (HO-1)
Protein Heme oxygenase-1 (HO-1) from a.132.1.1: Eukaryotic type heme oxygenase appears in SCOPe 2.07