SCOPe 2.08: Family a.128.1.2: Squalene synthase

Lineage for Family a.128.1.2: Squalene synthase

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.2: Squalene synthase [48580] (2 proteins)
   automatically mapped to Pfam PF00494

Proteins:

1. Squalene synthase [48581] (1 species)
   synonym: Farnesyl diphosphate farnesyltransferase

   • Species Human (Homo sapiens) [TaxId:9606] [48582] (1 PDB entry)

2. automated matches [191305] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [190011] (24 PDB entries)

More info for Family a.128.1.2: Squalene synthase

Timeline for Family a.128.1.2: Squalene synthase:

• Family a.128.1.2: Squalene synthase first appeared (with stable ids) in SCOP 1.55
  
• Family a.128.1.2: Squalene synthase appears in SCOPe 2.07