SCOPe 2.08: Family a.128.1.1: Isoprenyl diphosphate synthases

Lineage for Family a.128.1.1: Isoprenyl diphosphate synthases

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.1: Isoprenyl diphosphate synthases [48577] (4 proteins)

Proteins:

1. Farnesyl diphosphate synthase (geranyltranstransferase) [48578] (3 species)

   1. Species Chicken (Gallus gallus) [TaxId:9031] [48579] (5 PDB entries)

   2. Species Escherichia coli [TaxId:562] [101453] (2 PDB entries)

   3. Species Staphylococcus aureus [TaxId:1280] [101454] (1 PDB entry)

2. Geranylgeranyl pyrophosphate synthetase [158813] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [158814] (5 PDB entries)
     Uniprot O95749 6-296

3. Octoprenyl-diphosphate synthase [101455] (1 species)

   • Species Thermotoga maritima [TaxId:2336] [101456] (10 PDB entries)
     Uniprot Q9X1M1

4. automated matches [190489] (5 species)
   not a true protein

   1. Species Human (Homo sapiens) [TaxId:9606] [187688] (85 PDB entries)

   2. Species Shigella flexneri [TaxId:623] [225048] (1 PDB entry)

   3. Species Thermotoga maritima [TaxId:2336] [187431] (1 PDB entry)

   4. Species Thermotoga maritima [TaxId:243274] [188078] (1 PDB entry)

   5. Species Vibrio cholerae [TaxId:666] [189533] (1 PDB entry)

More info for Family a.128.1.1: Isoprenyl diphosphate synthases

Timeline for Family a.128.1.1: Isoprenyl diphosphate synthases:

• Family a.128.1.1: Isoprenyl diphosphate synthases first appeared (with stable ids) in SCOP 1.55
  
• Family a.128.1.1: Isoprenyl diphosphate synthases appears in SCOPe 2.07