Lineage for Family a.123.1.1: Nuclear receptor ligand-binding domain

  1. Root: SCOP 1.69
  2. 436025Class a: All alpha proteins [46456] (218 folds)
  3. 448073Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 448074Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family) (S)
  5. 448075Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (30 proteins)

Proteins:

  1. 448076Androgen receptor [63621] (3 species)
    1. 448077Species Chimpanzee (Pan troglodytes) [TaxId:9598] [109986] (8 PDB entries)
    2. 448086Species Human (Homo sapiens) [TaxId:9606] [63623] (1 PDB entry)
    3. 448088Species Rat (Rattus norvegicus) [TaxId:10116] [63622] (3 PDB entries)
  2. 448092Bile acid receptor FXR [101433] (2 species)
    1. 448093Species Human (Homo sapiens) [TaxId:9606] [101434] (1 PDB entry)
    2. 448095Species Rat (Rattus norvegicus) [TaxId:10116] [101435] (2 PDB entries)
  3. 448100Ecdysone receptor [101436] (1 species)
  4. 448104Estrogen receptor alpha [48519] (1 species)
  5. 448136Estrogen receptor beta [48521] (2 species)
    1. 448137Species Human (Homo sapiens) [TaxId:9606] [48522] (3 PDB entries)
    2. 448142Species Rat (Rattus norvegicus) [TaxId:10116] [48523] (2 PDB entries)
  6. 448145Glucocorticoid receptor [89140] (1 species)
  7. 448154Hepatocyte nuclear factor 4-alpha [109605] (2 species)
    1. 448155Species Human (Homo sapiens) [TaxId:9606] [109987] (1 PDB entry)
    2. 448157Species Rat (Rattus norvegicus) [TaxId:10116] [89146] (1 PDB entry)
  8. 448162Hepatocyte nuclear factor 4-gamma [81918] (1 species)
  9. 448165Nuclear hormone receptor HR38 [89144] (1 species)
  10. 448169Orphan nuclear receptor ERR3 [81916] (1 species)
  11. 448183Orphan nuclear receptor NR5a2 (LRH-1) [89147] (1 species)
  12. 448187Orphan nuclear receptor NURR1 [89142] (1 species)
  13. 448195Orphan nuclear receptor ROR-alpha [81914] (1 species)
  14. 448199Orphan nuclear receptor ROR-beta [74794] (1 species)
  15. 448204Oxysterols receptor LXR-alpha [109988] (1 species)
  16. 448207Oxysterols receptor LXR-beta [89149] (1 species)
  17. 448223Peroxisome proliferator activated receptor alpha, PPAR-alpha [69109] (1 species)
  18. 448234Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)
  19. 448256Peroxisome proliferator-activated receptor delta, PPAR-DELTA [48526] (1 species)
  20. 448264Pregnane x receptor, PXR [63624] (1 species)
  21. 448271Progesterone receptor [48517] (1 species)
  22. 448281Retinoic acid receptor alpha (RAR-alpha) [48513] (1 species)
  23. 448284Retinoic acid receptor gamma (RAR-gamma) [48515] (1 species)
  24. 448295Retinoid-X receptor alpha (RXR-alpha) [48510] (2 species)
    1. 448296Species Human (Homo sapiens) [TaxId:9606] [48511] (10 PDB entries)
    2. 448318Species Mouse (Mus musculus) [TaxId:10090] [48512] (1 PDB entry)
  25. 448320Retinoid-X receptor beta (RXR-beta) [74792] (1 species)
  26. 448327Steroid hormone receptor ERR1 [109990] (1 species)
  27. 448330Thyroid hormone receptor alpha1 (TR-alpha1) [48532] (1 species)
  28. 448333Thyroid hormone receptor beta (TR-beta) [48530] (1 species)
  29. 448345Ultraspiracle protein, usp [48534] (2 species)
    the ortholog of RXRs in insects
    1. 448346Species Drosophila melanogaster [TaxId:7227] [48535] (1 PDB entry)
    2. 448353Species Heliothis virescens [TaxId:7102] [63626] (3 PDB entries)
  30. 448357Vitamin D nuclear receptor [48528] (2 species)
    1. 448358Species Human (Homo sapiens) [TaxId:9606] [48529] (5 PDB entries)
    2. 448364Species Rat (Rattus norvegicus) [TaxId:10116] [101432] (4 PDB entries)

More info for Family a.123.1.1: Nuclear receptor ligand-binding domain

Timeline for Family a.123.1.1: Nuclear receptor ligand-binding domain: