SCOPe 2.06: Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain

Lineage for Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.121: Tetracyclin repressor-like, C-terminal domain [48497] (1 superfamily)
   multihelical; interlocked (homo)dimer

4. Superfamily a.121.1: Tetracyclin repressor-like, C-terminal domain [48498] (2 families)

5. Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain [48499] (35 proteins)

Proteins:

1. A-factor receptor homolog CprB [109980] (1 species)
   gamma-butyrolactone receptor

   • Species Streptomyces coelicolor [TaxId:1902] [109981] (2 PDB entries)
     Uniprot O66122

2. Ethr repressor [109978] (2 species)

   1. Species Mycobacterium tuberculosis [TaxId:1773] [109979] (34 PDB entries)
      Uniprot P96222 22-215

   2. Species Mycobacterium tuberculosis [TaxId:419947] [332341] (4 PDB entries)

3. Hemolysin II regulatory protein, HlyIIR [140889] (1 species)

   • Species Bacillus cereus [TaxId:1396] [140890] (1 PDB entry)
     Uniprot Q7X506 77-198

4. Hypothetical transcriptional regulator YcdC [89136] (1 species)

   • Species Escherichia coli [TaxId:562] [89137] (4 PDB entries)

5. Hypothetical transcriptional regulator YfiR [101430] (1 species)

   • Species Bacillus subtilis [TaxId:1423] [101431] (1 PDB entry)

6. Hypothetical transcriptional regulator YsiA [101428] (1 species)

   • Species Bacillus subtilis [TaxId:1423] [101429] (1 PDB entry)

7. Multidrug binding protein QacR [69107] (1 species)

   • Species Staphylococcus aureus [TaxId:1280] [69108] (24 PDB entries)
     Uniprot P23217

8. Probable transcriptional regulator PA1836 [140881] (1 species)

   • Species Pseudomonas aeruginosa [TaxId:287] [140882] (1 PDB entry)
     Uniprot Q9I2Q9 76-193

9. Probable transcriptional regulator PA3133 [140893] (1 species)

   • Species Pseudomonas aeruginosa [TaxId:287] [140894] (1 PDB entry)
     Uniprot Q9HZ91 77-180

10. Probable transcriptional regulator RHA1_ro04631 [140899] (1 species)

    • Species Rhodococcus sp. RHA1 [TaxId:101510] [140900] (1 PDB entry)
      Uniprot Q0S7R9 81-199

11. Putative regulator SCO4008 [140883] (1 species)

    • Species Streptomyces coelicolor [TaxId:1902] [140884] (1 PDB entry)
      Uniprot Q9ADP7 75-192

12. Putative regulatory protein Sco4313 [158800] (1 species)

    • Species Streptomyces coelicolor [TaxId:1902] [158801] (1 PDB entry)
      Uniprot Q9KXS8 87-216

13. Putative transcriptional regulator [140909] (1 species)

    • Species Rhodococcus sp. RHA1 [TaxId:101510] [140910] (1 PDB entry)

14. Putative transcriptional regulator Atu0279 [140911] (1 species)

    • Species Agrobacterium tumefaciens [TaxId:358] [140912] (1 PDB entry)
      Uniprot Q8UIL4 77-192

15. Putative transcriptional regulator Rha04620 [140903] (1 species)

    • Species Rhodococcus sp. RHA1 [TaxId:101510] [140904] (1 PDB entry)

16. Putative transcriptional regulator RHA1_ro03468 [158806] (1 species)

    • Species Rhodococcus sp. RHA1 [TaxId:101510] [158807] (1 PDB entry)
      Uniprot Q0SB15 88-208

17. Putative transcriptional regulator RHA1_ro09068 [140879] (1 species)

    • Species Rhodococcus sp. [TaxId:1831] [140880] (1 PDB entry)
      Uniprot Q0RX74 79-194

18. Putative transcriptional regulator SCO0857 [140887] (1 species)

    • Species Streptomyces coelicolor [TaxId:1902] [140888] (1 PDB entry)
      Uniprot Q9RCV4 100-211

19. Putative transcriptional regulator SCO4850 [158796] (1 species)

    • Species Streptomyces coelicolor [TaxId:1902] [158797] (1 PDB entry)
      Uniprot Q9KZ96 90-235

20. Putative transcriptional regulator SCO4940 [158798] (1 species)

    • Species Streptomyces coelicolor [TaxId:1902] [158799] (1 PDB entry)
      Uniprot Q8CJS4 83-200

21. Putative transcriptional regulator SCO5951 [140875] (1 species)

    • Species Streptomyces coelicolor [TaxId:1902] [140876] (1 PDB entry)
      Uniprot O54180 81-203

22. Putative transcriptional regulator SCO7704 [140885] (1 species)

    • Species Streptomyces coelicolor [TaxId:1902] [140886] (1 PDB entry)
      Uniprot Q93JG8 87-230

23. Putative transcriptional regulator YxaF [109984] (1 species)

    • Species Bacillus subtilis [TaxId:1423] [109985] (1 PDB entry)
      Uniprot P42105

24. Putative transcriptional repressor YbiH [109982] (1 species)

    • Species Salmonella typhimurium [TaxId:90371] [109983] (1 PDB entry)
      Uniprot Q8ZQN9

25. Tetracyclin repressor (Tet-repressor, TetR) [48500] (1 species)

    • Species Escherichia coli [TaxId:562] [48501] (28 PDB entries)

26. Transcriptional activator DhaS [158804] (1 species)

    • Species Lactococcus lactis [TaxId:1358] [158805] (1 PDB entry)
      Uniprot Q9CIV9 79-187

27. Transcriptional regulator BC3163 [140907] (1 species)

    • Species Bacillus cereus [TaxId:1396] [140908] (1 PDB entry)
      Uniprot Q81BJ4 78-192

28. Transcriptional regulator BC5000 [140891] (1 species)

    • Species Bacillus cereus [TaxId:1396] [140892] (1 PDB entry)
      Uniprot Q815X4 78-182

29. Transcriptional regulator Cgl1640/Cg1846 [158802] (1 species)

    • Species Corynebacterium glutamicum [TaxId:1718] [158803] (1 PDB entry)
      Uniprot Q8NQ14 79-188

30. Transcriptional regulator Cgl2612 [140895] (1 species)

    • Species Corynebacterium glutamicum [TaxId:1718] [140896] (5 PDB entries)
      Uniprot Q8NMG3 75-175

31. Transcriptional regulator EF0787 [140897] (1 species)

    • Species Enterococcus faecalis [TaxId:1351] [140898] (1 PDB entry)
      Uniprot Q837P6 72-220

32. Transcriptional regulator PsrA [140901] (1 species)

    • Species Pseudomonas aeruginosa [TaxId:287] [140902] (1 PDB entry)
      Uniprot Q9HZJ9 81-214

33. Transcriptional regulator RHA1_ro04179 [140905] (1 species)

    • Species Rhodococcus sp. [TaxId:1831] [140906] (1 PDB entry)
      Uniprot Q0S914 9-195

34. Transcriptional regulator TM1030 [140877] (1 species)

    • Species Thermotoga maritima [TaxId:2336] [140878] (8 PDB entries)
      Uniprot Q9X0C0 76-200

35. automated matches [226970] (7 species)
    not a true protein

    1. Species Bacillus cereus [TaxId:1396] [230945] (3 PDB entries)

    2. Species Bacillus subtilis [TaxId:224308] [267908] (2 PDB entries)

    3. Species Escherichia coli [TaxId:562] [226229] (9 PDB entries)

    4. Species Escherichia coli [TaxId:83333] [316668] (1 PDB entry)

    5. Species Mycobacterium tuberculosis [TaxId:1773] [232226] (7 PDB entries)

    6. Species Mycobacterium tuberculosis [TaxId:83331] [313824] (9 PDB entries)

    7. Species Streptomyces coelicolor [311234] (1 PDB entry)

More info for Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain

Timeline for Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain:

• Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain first appeared (with stable ids) in SCOP 1.55, called Family a.121.1.1: Tetracyclin repressor (Tet-repressor, TetR), C-terminal domain
  
• Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain appears in SCOPe 2.05
  
• Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain appears in SCOPe 2.07
  
• Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain appears in the current release, SCOPe 2.08