SCOP 1.75: Protein: Protein farnesyltransferase, beta-subunit

Lineage for Protein: Protein farnesyltransferase, beta-subunit

Root: SCOP 1.75
Class a: All alpha proteins [46456] (284 folds)

Fold a.102: alpha/alpha toroid [48207] (6 superfamilies)
multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

Superfamily a.102.4: Terpenoid cyclases/Protein prenyltransferases [48239] (4 families)
Family a.102.4.3: Protein prenyltransferases [48246] (2 proteins)
Protein Protein farnesyltransferase, beta-subunit [48247] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [69090] (19 PDB entries)
Uniprot P49356
1. Domain for 1jcq:
  - Domain d1jcqb_: 1jcq B: [66505]
    Other proteins in same PDB: d1jcqa_
    complexed with 739, acy, fpp, suc, zn; mutant
2. Domain for 1ld7:
  - Domain d1ld7b_: 1ld7 B: [73837]
    Other proteins in same PDB: d1ld7a_
    complexed with fpp, suc, u66, zn
3. Domain for 1ld8:
  - Domain d1ld8b_: 1ld8 B: [73839]
    Other proteins in same PDB: d1ld8a_
    complexed with acy, fpp, suc, u49, zn
4. Domain for 1mzc:
  - Domain d1mzcb_: 1mzc B: [85240]
    Other proteins in same PDB: d1mzca_
    complexed with bne, fpp, suc, zn
5. Domain for 1s63:
  - Domain d1s63b_: 1s63 B: [105286]
    Other proteins in same PDB: d1s63a_
    complexed with 778, fpp, suc, zn
6. Domain for 1sa4:
  - Domain d1sa4b_: 1sa4 B: [105403]
    Other proteins in same PDB: d1sa4a_
    complexed with fpp, jan, suc, zn
7. Domain for 1tn6:
  - Domain d1tn6b_: 1tn6 B: [112528]
    Other proteins in same PDB: d1tn6a_
    complexed with acy, fii, suc, zn; mutant
8. Domain for 1tn7:
  - Domain d1tn7b_: 1tn7 B: [112530]
    Other proteins in same PDB: d1tn7a_
    complexed with acy, fii, zn
9. Domain for 1tn8:
  - Domain d1tn8b_: 1tn8 B: [112532]
    Other proteins in same PDB: d1tn8a_
    complexed with acy, fii, zn; mutant
10. Domains for 1tnb:
  1. Domain d1tnbb_: 1tnb B: [112534]
    Other proteins in same PDB: d1tnba_, d1tnbc_, d1tnbe_, d1tnbg_, d1tnbi_, d1tnbk_
  2. Domain d1tnbd_: 1tnb D: [112536]
    Other proteins in same PDB: d1tnba_, d1tnbc_, d1tnbe_, d1tnbg_, d1tnbi_, d1tnbk_
  3. Domain d1tnbf_: 1tnb F: [112538]
    Other proteins in same PDB: d1tnba_, d1tnbc_, d1tnbe_, d1tnbg_, d1tnbi_, d1tnbk_
  4. Domain d1tnbh_: 1tnb H: [112540]
    Other proteins in same PDB: d1tnba_, d1tnbc_, d1tnbe_, d1tnbg_, d1tnbi_, d1tnbk_
  5. Domain d1tnbj_: 1tnb J: [112542]
    Other proteins in same PDB: d1tnba_, d1tnbc_, d1tnbe_, d1tnbg_, d1tnbi_, d1tnbk_
  6. Domain d1tnbl_: 1tnb L: [112544]
    Other proteins in same PDB: d1tnba_, d1tnbc_, d1tnbe_, d1tnbg_, d1tnbi_, d1tnbk_
    complexed with cl, mes, mgm, zn
11. Domains for 1tno:
  1. Domain d1tnob_: 1tno B: [112546]
    Other proteins in same PDB: d1tnoa_, d1tnoc_, d1tnoe_, d1tnog_, d1tnoi_, d1tnok_
  2. Domain d1tnod_: 1tno D: [112548]
    Other proteins in same PDB: d1tnoa_, d1tnoc_, d1tnoe_, d1tnog_, d1tnoi_, d1tnok_
  3. Domain d1tnof_: 1tno F: [112550]
    Other proteins in same PDB: d1tnoa_, d1tnoc_, d1tnoe_, d1tnog_, d1tnoi_, d1tnok_
  4. Domain d1tnoh_: 1tno H: [112552]
    Other proteins in same PDB: d1tnoa_, d1tnoc_, d1tnoe_, d1tnog_, d1tnoi_, d1tnok_
  5. Domain d1tnoj_: 1tno J: [112554]
    Other proteins in same PDB: d1tnoa_, d1tnoc_, d1tnoe_, d1tnog_, d1tnoi_, d1tnok_
  6. Domain d1tnol_: 1tno L: [112556]
    Other proteins in same PDB: d1tnoa_, d1tnoc_, d1tnoe_, d1tnog_, d1tnoi_, d1tnok_
    complexed with cl, mes, mgm, zn
12. Domains for 1tnu:
  1. Domain d1tnub_: 1tnu B: [112558]
    Other proteins in same PDB: d1tnua_, d1tnuc_, d1tnue_, d1tnug_, d1tnui_, d1tnuk_
  2. Domain d1tnud_: 1tnu D: [112560]
    Other proteins in same PDB: d1tnua_, d1tnuc_, d1tnue_, d1tnug_, d1tnui_, d1tnuk_
  3. Domain d1tnuf_: 1tnu F: [112562]
    Other proteins in same PDB: d1tnua_, d1tnuc_, d1tnue_, d1tnug_, d1tnui_, d1tnuk_
  4. Domain d1tnuh_: 1tnu H: [112564]
    Other proteins in same PDB: d1tnua_, d1tnuc_, d1tnue_, d1tnug_, d1tnui_, d1tnuk_
  5. Domain d1tnuj_: 1tnu J: [112566]
    Other proteins in same PDB: d1tnua_, d1tnuc_, d1tnue_, d1tnug_, d1tnui_, d1tnuk_
  6. Domain d1tnul_: 1tnu L: [112568]
    Other proteins in same PDB: d1tnua_, d1tnuc_, d1tnue_, d1tnug_, d1tnui_, d1tnuk_
    complexed with cl, mes, mgm, zn
13. Domains for 1tny:
  1. Domain d1tnyb_: 1tny B: [112570]
    Other proteins in same PDB: d1tnya_, d1tnyc_, d1tnye_, d1tnyg_, d1tnyi_, d1tnyk_
  2. Domain d1tnyd_: 1tny D: [112572]
    Other proteins in same PDB: d1tnya_, d1tnyc_, d1tnye_, d1tnyg_, d1tnyi_, d1tnyk_
  3. Domain d1tnyf_: 1tny F: [112574]
    Other proteins in same PDB: d1tnya_, d1tnyc_, d1tnye_, d1tnyg_, d1tnyi_, d1tnyk_
  4. Domain d1tnyh_: 1tny H: [112576]
    Other proteins in same PDB: d1tnya_, d1tnyc_, d1tnye_, d1tnyg_, d1tnyi_, d1tnyk_
  5. Domain d1tnyj_: 1tny J: [112578]
    Other proteins in same PDB: d1tnya_, d1tnyc_, d1tnye_, d1tnyg_, d1tnyi_, d1tnyk_
  6. Domain d1tnyl_: 1tny L: [112580]
    Other proteins in same PDB: d1tnya_, d1tnyc_, d1tnye_, d1tnyg_, d1tnyi_, d1tnyk_
    complexed with cl, mes, mgm, zn
14. Domains for 1tnz:
  1. Domain d1tnzb_: 1tnz B: [112582]
    Other proteins in same PDB: d1tnza_, d1tnzc_, d1tnze_, d1tnzg_, d1tnzi_, d1tnzk_
  2. Domain d1tnzd_: 1tnz D: [112584]
    Other proteins in same PDB: d1tnza_, d1tnzc_, d1tnze_, d1tnzg_, d1tnzi_, d1tnzk_
  3. Domain d1tnzf_: 1tnz F: [112586]
    Other proteins in same PDB: d1tnza_, d1tnzc_, d1tnze_, d1tnzg_, d1tnzi_, d1tnzk_
  4. Domain d1tnzh_: 1tnz H: [112588]
    Other proteins in same PDB: d1tnza_, d1tnzc_, d1tnze_, d1tnzg_, d1tnzi_, d1tnzk_
  5. Domain d1tnzj_: 1tnz J: [112590]
    Other proteins in same PDB: d1tnza_, d1tnzc_, d1tnze_, d1tnzg_, d1tnzi_, d1tnzk_
  6. Domain d1tnzl_: 1tnz L: [112592]
    Other proteins in same PDB: d1tnza_, d1tnzc_, d1tnze_, d1tnzg_, d1tnzi_, d1tnzk_
    complexed with cl, mes, mgm, zn
15. Domain for 2f0y:
  - Domain d2f0yb1: 2f0y B:21-421 [132682]
    Other proteins in same PDB: d2f0ya1
    automatically matched to d1jcqb_
    complexed with 3mn, fpp, zn
16. Domain for 2h6f:
  - Domain d2h6fb1: 2h6f B:521-921 [136186]
    Other proteins in same PDB: d2h6fa1
    automatically matched to d1jcqb_
    complexed with acy, far, suc, zn; mutant
17. Domain for 2h6h:
  - Domain d2h6hb1: 2h6h B:515-924 [145283]
    Other proteins in same PDB: d2h6ha1
    complexed with acy, far, suc, zn; mutant
18. Domain for 2h6i:
  - Domain d2h6ib1: 2h6i B:515-924 [145284]
    Other proteins in same PDB: d2h6ia1
    complexed with ger, suc, zn; mutant
19. Domain for 2iej:
  - Domain d2iejb1: 2iej B:521-921 [137314]
    Other proteins in same PDB: d2ieja1
    automatically matched to d1jcqb_
    complexed with act, fii, s48, suc, zn
Rat (Rattus norvegicus) [TaxId:10116] [48248] (29 PDB entries)
Uniprot Q02293 22-418 P53610
1. Domain for 1d8d:
  - Domain d1d8db_: 1d8d B: [18866]
    Other proteins in same PDB: d1d8da_
    complex with K-ras4b peptide substrate
2. Domain for 1d8e:
  - Domain d1d8eb_: 1d8e B: [18869]
    Other proteins in same PDB: d1d8ea_
    complex with k-ras4b peptide substrate and FPP analog
    complexed with ace, fii
3. Domain for 1fpp:
  - Domain d1fppb_: 1fpp B: [18870]
    Other proteins in same PDB: d1fppa_
    complexed with fpp, po4, zn
4. Domain for 1ft1:
  - Domain d1ft1b_: 1ft1 B: [18867]
    Other proteins in same PDB: d1ft1a_
    complexed with zn
5. Domain for 1ft2:
  - Domain d1ft2b_: 1ft2 B: [18871]
    Other proteins in same PDB: d1ft2a_
    complexed with fpp, zn
6. Domain for 1jcr:
  - Domain d1jcrb_: 1jcr B: [66507]
    Other proteins in same PDB: d1jcra_
    complexed with acy, fpp, zn
7. Domain for 1jcs:
  - Domain d1jcsb_: 1jcs B: [66509]
    Other proteins in same PDB: d1jcsa_
    complexed with acy, fii, zn
8. Domain for 1kzo:
  - Domain d1kzob_: 1kzo B: [77639]
    Other proteins in same PDB: d1kzoa_
    complex with k-ras4b peptide product and farnesyl diphosphate substrate bound simultaneously
    complexed with acy, far, fpp, zn
9. Domain for 1kzp:
  - Domain d1kzpb_: 1kzp B: [77641]
    Other proteins in same PDB: d1kzpa_
    complex with k-ras4b peptide product
    complexed with acy, far, zn
10. Domains for 1n4p:
  1. Domain d1n4pb_: 1n4p B: [91624]
    Other proteins in same PDB: d1n4pa_, d1n4pc_, d1n4pe_, d1n4pg_, d1n4pi_, d1n4pk_
  2. Domain d1n4pd_: 1n4p D: [91626]
    Other proteins in same PDB: d1n4pa_, d1n4pc_, d1n4pe_, d1n4pg_, d1n4pi_, d1n4pk_
  3. Domain d1n4pf_: 1n4p F: [91628]
    Other proteins in same PDB: d1n4pa_, d1n4pc_, d1n4pe_, d1n4pg_, d1n4pi_, d1n4pk_
  4. Domain d1n4ph_: 1n4p H: [91630]
    Other proteins in same PDB: d1n4pa_, d1n4pc_, d1n4pe_, d1n4pg_, d1n4pi_, d1n4pk_
  5. Domain d1n4pj_: 1n4p J: [91632]
    Other proteins in same PDB: d1n4pa_, d1n4pc_, d1n4pe_, d1n4pg_, d1n4pi_, d1n4pk_
  6. Domain d1n4pl_: 1n4p L: [91634]
    Other proteins in same PDB: d1n4pa_, d1n4pc_, d1n4pe_, d1n4pg_, d1n4pi_, d1n4pk_
    complexed with cl, grg, tth, zn
11. Domains for 1n4q:
  1. Domain d1n4qb_: 1n4q B: [91636]
    Other proteins in same PDB: d1n4qa_, d1n4qc_, d1n4qe_, d1n4qg_, d1n4qi_, d1n4qk_
  2. Domain d1n4qd_: 1n4q D: [91638]
    Other proteins in same PDB: d1n4qa_, d1n4qc_, d1n4qe_, d1n4qg_, d1n4qi_, d1n4qk_
  3. Domain d1n4qf_: 1n4q F: [91640]
    Other proteins in same PDB: d1n4qa_, d1n4qc_, d1n4qe_, d1n4qg_, d1n4qi_, d1n4qk_
  4. Domain d1n4qh_: 1n4q H: [91642]
    Other proteins in same PDB: d1n4qa_, d1n4qc_, d1n4qe_, d1n4qg_, d1n4qi_, d1n4qk_
  5. Domain d1n4qj_: 1n4q J: [91644]
    Other proteins in same PDB: d1n4qa_, d1n4qc_, d1n4qe_, d1n4qg_, d1n4qi_, d1n4qk_
  6. Domain d1n4ql_: 1n4q L: [91646]
    Other proteins in same PDB: d1n4qa_, d1n4qc_, d1n4qe_, d1n4qg_, d1n4qi_, d1n4qk_
    complexed with cl, mgm, tth, zn
12. Domains for 1n4r:
  1. Domain d1n4rb_: 1n4r B: [91648]
    Other proteins in same PDB: d1n4ra_, d1n4rc_, d1n4re_, d1n4rg_, d1n4ri_, d1n4rk_
  2. Domain d1n4rd_: 1n4r D: [91650]
    Other proteins in same PDB: d1n4ra_, d1n4rc_, d1n4re_, d1n4rg_, d1n4ri_, d1n4rk_
  3. Domain d1n4rf_: 1n4r F: [91652]
    Other proteins in same PDB: d1n4ra_, d1n4rc_, d1n4re_, d1n4rg_, d1n4ri_, d1n4rk_
  4. Domain d1n4rh_: 1n4r H: [91654]
    Other proteins in same PDB: d1n4ra_, d1n4rc_, d1n4re_, d1n4rg_, d1n4ri_, d1n4rk_
  5. Domain d1n4rj_: 1n4r J: [91656]
    Other proteins in same PDB: d1n4ra_, d1n4rc_, d1n4re_, d1n4rg_, d1n4ri_, d1n4rk_
  6. Domain d1n4rl_: 1n4r L: [91658]
    Other proteins in same PDB: d1n4ra_, d1n4rc_, d1n4re_, d1n4rg_, d1n4ri_, d1n4rk_
    complexed with cl, mes, so4, tth, zn
13. Domains for 1n4s:
  1. Domain d1n4sb_: 1n4s B: [91660]
    Other proteins in same PDB: d1n4sa_, d1n4sc_, d1n4se_, d1n4sg_, d1n4si_, d1n4sk_
  2. Domain d1n4sd_: 1n4s D: [91662]
    Other proteins in same PDB: d1n4sa_, d1n4sc_, d1n4se_, d1n4sg_, d1n4si_, d1n4sk_
  3. Domain d1n4sf_: 1n4s F: [91664]
    Other proteins in same PDB: d1n4sa_, d1n4sc_, d1n4se_, d1n4sg_, d1n4si_, d1n4sk_
  4. Domain d1n4sh_: 1n4s H: [91666]
    Other proteins in same PDB: d1n4sa_, d1n4sc_, d1n4se_, d1n4sg_, d1n4si_, d1n4sk_
  5. Domain d1n4sj_: 1n4s J: [91668]
    Other proteins in same PDB: d1n4sa_, d1n4sc_, d1n4se_, d1n4sg_, d1n4si_, d1n4sk_
  6. Domain d1n4sl_: 1n4s L: [91670]
    Other proteins in same PDB: d1n4sa_, d1n4sc_, d1n4se_, d1n4sg_, d1n4si_, d1n4sk_
    complexed with cl, grg, tth, zn
14. Domain for 1n94:
  - Domain d1n94b_: 1n94 B: [80332]
    Other proteins in same PDB: d1n94a_
    complexed with hfp, tin, zn
15. Domain for 1n95:
  - Domain d1n95b_: 1n95 B: [80334]
    Other proteins in same PDB: d1n95a_
    complexed with fth, hfp, zn
16. Domain for 1n9a:
  - Domain d1n9ab_: 1n9a B: [80339]
    Other proteins in same PDB: d1n9aa_
    complexed with fti, hfp, zn
17. Domain for 1ni1:
  - Domain d1ni1b_: 1ni1 B: [91889]
    Other proteins in same PDB: d1ni1a_
    complexed with 2c5, hfp, zn
18. Domain for 1nl4:
  - Domain d1nl4b_: 1nl4 B: [80618]
    Other proteins in same PDB: d1nl4a_
    complexed with ftl, hfp, zn; mutant
19. Domain for 1o1r:
  - Domain d1o1rb_: 1o1r B: [86548]
    Other proteins in same PDB: d1o1ra_
    complexed with grg, zn
20. Domain for 1o1s:
  - Domain d1o1sb_: 1o1s B: [86550]
    Other proteins in same PDB: d1o1sa_
    complexed with 1nh, zn
21. Domain for 1o1t:
  - Domain d1o1tb_: 1o1t B: [86552]
    Other proteins in same PDB: d1o1ta_
    complexed with 2nh, mg, zn
22. Domain for 1o5m:
  - Domain d1o5mb_: 1o5m B: [92508]
    Other proteins in same PDB: d1o5ma_
    complexed with 336, fpp, zn
23. Domain for 1qbq:
  - Domain d1qbqb_: 1qbq B: [18868]
    Other proteins in same PDB: d1qbqa_
    complexed with ace, act, hfp, zn
24. Domains for 1s64:
  1. Domain d1s64b_: 1s64 B: [105288]
    Other proteins in same PDB: d1s64a_, d1s64c_, d1s64e_, d1s64g_, d1s64i_, d1s64k_
  2. Domain d1s64d_: 1s64 D: [105290]
    Other proteins in same PDB: d1s64a_, d1s64c_, d1s64e_, d1s64g_, d1s64i_, d1s64k_
  3. Domain d1s64f_: 1s64 F: [105292]
    Other proteins in same PDB: d1s64a_, d1s64c_, d1s64e_, d1s64g_, d1s64i_, d1s64k_
  4. Domain d1s64h_: 1s64 H: [105294]
    Other proteins in same PDB: d1s64a_, d1s64c_, d1s64e_, d1s64g_, d1s64i_, d1s64k_
  5. Domain d1s64j_: 1s64 J: [105296]
    Other proteins in same PDB: d1s64a_, d1s64c_, d1s64e_, d1s64g_, d1s64i_, d1s64k_
  6. Domain d1s64l_: 1s64 L: [105298]
    Other proteins in same PDB: d1s64a_, d1s64c_, d1s64e_, d1s64g_, d1s64i_, d1s64k_
    complexed with 778, cl, mes, so4, zn
25. Domain for 1sa5:
  - Domain d1sa5b_: 1sa5 B: [105405]
    Other proteins in same PDB: d1sa5a_
    complexed with acy, bmv, fpp, zn
26. Domain for 1x81:
  - Domain d1x81b_: 1x81 B: [114954]
    Other proteins in same PDB: d1x81a_
    complexed with jan, zn
27. Domain for 2bed:
  - Domain d2bedb1: 2bed B:23-423 [128376]
    Other proteins in same PDB: d2beda1
    automatically matched to d1ft1b_
    complexed with 736, fpp, zn
28. Domain for 2r2l:
  - Domain d2r2lb1: 2r2l B:23-423 [151536]
    Other proteins in same PDB: d2r2la1
    automatically matched to d1ft1b_
    complexed with fpp, pb9, zn
29. Domain for 3dpy:
  - Domain d3dpyb1: 3dpy B:22-423 [157826]
    Other proteins in same PDB: d3dpya1
    automatically matched to d1ft1b_
    complexed with acy, fpp, zn

More info for Protein Protein farnesyltransferase, beta-subunit from a.102.4.3: Protein prenyltransferases

Timeline for Protein Protein farnesyltransferase, beta-subunit from a.102.4.3: Protein prenyltransferases:

Protein Protein farnesyltransferase, beta-subunit from a.102.4.3: Protein prenyltransferases first appeared (with stable ids) in SCOP 1.55
Protein Protein farnesyltransferase, beta-subunit from a.102.4.3: Protein prenyltransferases appears in SCOP 1.73
Protein Protein farnesyltransferase, beta-subunit from a.102.4.3: Protein prenyltransferases appears in SCOPe 2.01
Protein Protein farnesyltransferase, beta-subunit from a.102.4.3: Protein prenyltransferases appears in the current release, SCOPe 2.08