SCOPe 2.08: Protein: Short chain L-3-hydroxyacyl CoA dehydrogenase

Lineage for Protein: Short chain L-3-hydroxyacyl CoA dehydrogenase

Root: SCOPe 2.08
Class a: All alpha proteins [46456] (290 folds)

Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry

Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (13 families)
N-terminal domain is Rossmann-fold with a family-specific C-terminal extension
Family a.100.1.3: HCDH C-domain-like [48187] (2 proteins)
Protein Short chain L-3-hydroxyacyl CoA dehydrogenase [48188] (2 species)
Dimer of 5-helical motifs; similar to duplicated motifs of 6PGD and KARI

Species:

Human (Homo sapiens) [TaxId:9606] [48189] (11 PDB entries)
1. Domains for 1f0y:
  1. Domain d1f0ya1: 1f0y A:204-302 [18793]
    Other proteins in same PDB: d1f0ya2, d1f0yb2
    complexed with caa, nad
  2. Domain d1f0yb1: 1f0y B:204-302 [18794]
    Other proteins in same PDB: d1f0ya2, d1f0yb2
    complexed with caa, nad
2. Domains for 1f12:
  1. Domain d1f12a1: 1f12 A:204-302 [18803]
    Other proteins in same PDB: d1f12a2, d1f12a3, d1f12b2
    complexed with 3hc
  2. Domain d1f12b1: 1f12 B:204-302 [18804]
    Other proteins in same PDB: d1f12a2, d1f12a3, d1f12b2
    complexed with 3hc
3. Domains for 1f14:
  1. Domain d1f14a1: 1f14 A:204-302 [18801]
    Other proteins in same PDB: d1f14a2, d1f14b2
  2. Domain d1f14b1: 1f14 B:204-302 [18802]
    Other proteins in same PDB: d1f14a2, d1f14b2
4. Domains for 1f17:
  1. Domain d1f17a1: 1f17 A:204-302 [18797]
    Other proteins in same PDB: d1f17a2, d1f17a3, d1f17b2
    complexed with nai
  2. Domain d1f17b1: 1f17 B:204-302 [18798]
    Other proteins in same PDB: d1f17a2, d1f17a3, d1f17b2
    complexed with nai
5. Domains for 1il0:
  1. Domain d1il0a1: 1il0 A:204-302 [66189]
    Other proteins in same PDB: d1il0a2, d1il0b2
    complexed with caa, nad; mutant
  2. Domain d1il0b1: 1il0 B:204-302 [66191]
    Other proteins in same PDB: d1il0a2, d1il0b2
    complexed with caa, nad; mutant
6. Domains for 1lsj:
  1. Domain d1lsja1: 1lsj A:204-302 [91116]
    Other proteins in same PDB: d1lsja2, d1lsjb2
    complexed with nad; mutant
  2. Domain d1lsjb1: 1lsj B:204-302 [91118]
    Other proteins in same PDB: d1lsja2, d1lsjb2
    complexed with nad; mutant
7. Domains for 1lso:
  1. Domain d1lsoa1: 1lso A:204-302 [91120]
    Other proteins in same PDB: d1lsoa2, d1lsob2
    complexed with nad; mutant
  2. Domain d1lsob1: 1lso B:204-302 [91122]
    Other proteins in same PDB: d1lsoa2, d1lsob2
    complexed with nad; mutant
8. Domains for 1m75:
  1. Domain d1m75a1: 1m75 A:204-302 [91212]
    Other proteins in same PDB: d1m75a2, d1m75b2
    complexed with caa, nad; mutant
  2. Domain d1m75b1: 1m75 B:204-302 [91214]
    Other proteins in same PDB: d1m75a2, d1m75b2
    complexed with caa, nad; mutant
9. Domains for 1m76:
  1. Domain d1m76a1: 1m76 A:204-302 [91216]
    Other proteins in same PDB: d1m76a2, d1m76b2
    complexed with caa, nad; mutant
  2. Domain d1m76b1: 1m76 B:204-302 [91218]
    Other proteins in same PDB: d1m76a2, d1m76b2
    complexed with caa, nad; mutant
10. Domains for 2hdh:
  1. Domain d2hdha1: 2hdh A:204-304 [18795]
    Other proteins in same PDB: d2hdha2, d2hdhb2
    complexed with nad
  2. Domain d2hdhb1: 2hdh B:204-302 [18796]
    Other proteins in same PDB: d2hdha2, d2hdhb2
    complexed with nad
11. Domains for 3had:
  1. Domain d3hada1: 3had A:204-302 [18799]
    Other proteins in same PDB: d3hada2, d3hada3, d3hadb2
    complexed with nad
  2. Domain d3hadb1: 3had B:204-302 [18800]
    Other proteins in same PDB: d3hada2, d3hada3, d3hadb2
    complexed with nad
Pig (Sus scrofa) [TaxId:9823] [48190] (1 PDB entry)
- Domains for 3hdh:
  1. Domain d3hdha1: 3hdh A:204-302 [18805]
    Other proteins in same PDB: d3hdha2, d3hdhb2, d3hdhc2
    complexed with nad
  2. Domain d3hdhb1: 3hdh B:204-302 [18806]
    Other proteins in same PDB: d3hdha2, d3hdhb2, d3hdhc2
    complexed with nad
  3. Domain d3hdhc1: 3hdh C:204-295 [18807]
    Other proteins in same PDB: d3hdha2, d3hdhb2, d3hdhc2
    complexed with nad

More info for Protein Short chain L-3-hydroxyacyl CoA dehydrogenase from a.100.1.3: HCDH C-domain-like

Timeline for Protein Short chain L-3-hydroxyacyl CoA dehydrogenase from a.100.1.3: HCDH C-domain-like:

Protein Short chain L-3-hydroxyacyl CoA dehydrogenase from a.100.1.3: HCDH C-domain-like first appeared (with stable ids) in SCOP 1.55, called Protein Short chain L-3-hydroxyacyl CoA dehydrogenase from a.100.1.3: Short chain L-3-hydroxyacyl CoA dehydrogenase
Protein Short chain L-3-hydroxyacyl CoA dehydrogenase from a.100.1.3: HCDH C-domain-like appears in SCOPe 2.07