Lineage for Protein: 6-phosphogluconate dehydrogenase (6PGD)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2721323Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
    multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry
  4. 2721324Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (13 families) (S)
    N-terminal domain is Rossmann-fold with a family-specific C-terminal extension
  5. 2721325Family a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain [48180] (3 proteins)
    Hydroxyisobutyrate dehydrogenase domain is similar to one structural repeat in the 6-phosphogluconate dehydrogenase domain
  6. 2721326Protein 6-phosphogluconate dehydrogenase (6PGD) [48181] (2 species)
    duplication; contains two structural repeats

Species:

  1. 2721327Sheep (Ovis orientalis aries) [TaxId:9940] [48182] (5 PDB entries)
    1. Domain for 1pgn:
      • 2721329Domain d1pgna1: 1pgn A:177-473 [18781]
        Other proteins in same PDB: d1pgna2
        complexed with nbp, pop, so4
        multiple common domains: applies to families that are inconsistently divided into domains
    2. Domain for 1pgo:
      • 2721331Domain d1pgoa1: 1pgo A:177-473 [18779]
        Other proteins in same PDB: d1pgoa2
        complexed with ndp, so4
        multiple common domains: applies to families that are inconsistently divided into domains
    3. Domain for 1pgp:
      • 2721330Domain d1pgpa1: 1pgp A:177-473 [18780]
        Other proteins in same PDB: d1pgpa2
        complexed with 6pg, so4
        multiple common domains: applies to families that are inconsistently divided into domains
    4. Domain for 1pgq:
      • 2721332Domain d1pgqa1: 1pgq A:177-473 [18782]
        Other proteins in same PDB: d1pgqa2
        complexed with 2am, so4
        multiple common domains: applies to families that are inconsistently divided into domains
    5. Domain for 2pgd:
      • 2721328Domain d2pgda1: 2pgd A:177-473 [18778]
        Other proteins in same PDB: d2pgda2
        complexed with so4
        multiple common domains: applies to families that are inconsistently divided into domains
  2. 2721333Trypanosome (Trypanosoma brucei) [TaxId:5691] [48183] (1 PDB entry)
    • Domains for 1pgj:
      1. 2721334Domain d1pgja1: 1pgj A:179-478 [18783]
        Other proteins in same PDB: d1pgja2, d1pgjb2
        complexed with so4
        multiple common domains: applies to families that are inconsistently divided into domains
      2. 2721335Domain d1pgjb1: 1pgj B:179-478 [18784]
        Other proteins in same PDB: d1pgja2, d1pgjb2
        complexed with so4
        multiple common domains: applies to families that are inconsistently divided into domains

More info for Protein 6-phosphogluconate dehydrogenase (6PGD) from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain

Timeline for Protein 6-phosphogluconate dehydrogenase (6PGD) from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain: