Class a: All alpha proteins [46456] (286 folds) |
Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily) multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry |
Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (13 families) N-terminal domain is Rossmann-fold with a family-specific C-terminal extension |
a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain [48180] (3 proteins) Hydroxyisobutyrate dehydrogenase domain is similar to one structural repeat in the 6-phosphogluconate dehydrogenase domain |
a.100.1.2: Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI) [48184] (3 proteins) |
a.100.1.3: HCDH C-domain-like [48187] (2 proteins) |
a.100.1.4: UDP-glucose/GDP-mannose dehydrogenase dimerisation domain [48191] (2 proteins) automatically mapped to Pfam PF00984 |
a.100.1.5: N-(1-D-carboxylethyl)-L-norvaline dehydrogenase [48194] (1 protein) automatically mapped to Pfam PF02317 |
a.100.1.6: Glycerol-3-phosphate dehydrogenase [48197] (1 protein) automatically mapped to Pfam PF07479 |
a.100.1.7: Ketopantoate reductase PanE [69084] (1 protein) automatically mapped to Pfam PF08546 |
a.100.1.8: Conserved hypothetical protein MTH1747 [74762] (1 protein) |
a.100.1.9: Mannitol 2-dehydrogenase [81843] (1 protein) |
a.100.1.10: ProC C-terminal domain-like [116984] (2 proteins) similar dimer to the class I KARI |
a.100.1.11: HMD dimerization domain-like [140777] (1 protein) dimer similar to those of the GDP-mannose 6-dehydrogenase and class I KARI domains automatically mapped to Pfam PF03201 |
a.100.1.12: TyrA dimerization domain-like [140780] (1 protein) new dimerisation mode with swapping of C-terminal helices |
a.100.1.0: automated matches [227147] (1 protein) not a true family |
Timeline for Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like: