Lineage for Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like

  1. Root: SCOP 1.71
  2. 530466Class a: All alpha proteins [46456] (226 folds)
  3. 541599Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
    multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry
  4. 541600Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (10 families) (S)
    N-terminal domain is Rossmann-fold with a family-specific C-terminal extension

Families:

  1. 541601a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain [48180] (2 proteins)
    Hydroxyisobutyrate dehydrogenase domain is similar to one structural repeat in the 6-phosphogluconate dehydrogenase domain
  2. 541620a.100.1.2: Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI) [48184] (2 proteins)
  3. 541637a.100.1.3: HCDH C-domain-like [48187] (2 proteins)
  4. 541680a.100.1.4: UDP-glucose/GDP-mannose dehydrogenase dimerisation domain [48191] (2 proteins)
  5. 541699a.100.1.5: N-(1-D-carboxylethyl)-L-norvaline dehydrogenase [48194] (1 protein)
  6. 541703a.100.1.6: Glycerol-3-phosphate dehydrogenase [48197] (1 protein)
  7. 541717a.100.1.7: Ketopantoate reductase PanE [69084] (1 protein)
  8. 541721a.100.1.8: Conserved hypothetical protein MTH1747 [74762] (1 protein)
  9. 541726a.100.1.9: Mannitol 2-dehydrogenase [81843] (1 protein)
  10. 541732a.100.1.10: Pyrroline-5-carboxylate reductase ProC [116984] (1 protein)
    similar dimer to the class I KARI

More info for Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like

Timeline for Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like: