Lineage for Family a.91.1.1: Regulator of G-protein signaling, RGS

  1. Root: SCOPe 2.08
  2. Class a: All alpha proteins [46456] (290 folds)
  3. Fold a.91: Regulator of G-protein signaling, RGS [48096] (1 superfamily)
    multihelical; consists of two all-alpha subdomains
    contains a 4-helical bundle with left-handed twist and up-and-down topology
  4. Superfamily a.91.1: Regulator of G-protein signaling, RGS [48097] (2 families) (S)
  5. Family a.91.1.1: Regulator of G-protein signaling, RGS [48098] (10 proteins)

Proteins:

  1. Axin RGS-homologous domain [48105] (1 species)
  2. G-protein coupled receptor kinase 2, N-terminal domain [89090] (1 species)
  3. Galpha interacting protein, GaIP [48103] (1 species)
  4. p115RhoGEF [63584] (1 species)
  5. Pdz-RhoGEF RGS-like domain [63586] (1 species)
    contains extra helices in the C-terminal extension
  6. Regulator of G-protein signaling 16, RGS16 [158689] (2 species)
    1. Species Human (Homo sapiens) [TaxId:9606] [158690] (1 PDB entry)
      Uniprot O15492 65-184
    2. Species Mouse (Mus musculus) [TaxId:10090] [188430] (2 PDB entries)
  7. Regulator of G-protein signaling 18, RGS18 [140750] (1 species)
  8. Regulator of G-protein signaling 4, RGS4 [48099] (1 species)
  9. RGS9, RGS domain [48101] (1 species)
  10. automated matches [190756] (2 species)
    not a true protein
    1. Species Human (Homo sapiens) [TaxId:9606] [187954] (3 PDB entries)
    2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [188643] (3 PDB entries)

More info for Family a.91.1.1: Regulator of G-protein signaling, RGS

Timeline for Family a.91.1.1: Regulator of G-protein signaling, RGS: