SCOPe 2.08: Family a.60.1.2: SAM (sterile alpha motif) domain

Lineage for Family a.60.1.2: SAM (sterile alpha motif) domain

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.60: SAM domain-like [47768] (17 superfamilies)
   4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

4. Superfamily a.60.1: SAM/Pointed domain [47769] (4 families)

5. Family a.60.1.2: SAM (sterile alpha motif) domain [47773] (16 proteins)

Proteins:

1. C-terminal domain of p63 [116934] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [116935] (1 PDB entry)
     Uniprot Q9H3D4 544-610

2. C-terminal domain of p73 [47779] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [47780] (2 PDB entries)

3. Centaurin-delta 1 (Arap2) [140624] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [140625] (1 PDB entry)
     Uniprot Q8WZ64 1-78

4. Connector enhancer of kinase suppressor of Ras 1, CNK1 [140618] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [140619] (1 PDB entry)
     Uniprot Q969H4 1-78

5. EphA4 receptor tyrosine kinases [47774] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [47775] (1 PDB entry)

6. EphB2 receptor [47776] (2 species)

   1. Species Chicken (Gallus gallus) [TaxId:9031] [47778] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [47777] (2 PDB entries)

7. Ephrin type-A receptor 8, C-terminal domain [101242] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [101243] (1 PDB entry)

8. Polycomb protein Scm [140620] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [140621] (2 PDB entries)
     Uniprot Q9VHA0 795-871

9. Polyhomeotic [74737] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [74738] (2 PDB entries)

10. RNA-binding protein Smaug [89075] (1 species)

    • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [89076] (1 PDB entry)

11. Sam-domain protein samsn-1 [101248] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [101249] (1 PDB entry)

12. Serine/threonine-protein kinase ste11 [101246] (1 species)

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [101247] (2 PDB entries)

13. Sh3 and multiple ankyrin repeat domains 3 (Shank3) [140616] (1 species)

    • Species Norway rat (Rattus norvegicus) [TaxId:10116] [140617] (2 PDB entries)
      Uniprot Q9JLU4 1749-1815

14. Sphingomyelin synthase 1, SMS1 [140622] (1 species)
    Phosphatidylcholine:ceramide cholinephosphotransferase 1

    • Species Mouse (Mus musculus) [TaxId:10090] [140623] (1 PDB entry)
      Uniprot Q8VCQ6 1-84

15. Ste50p, N-terminal domain [101244] (1 species)

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [101245] (2 PDB entries)

16. automated matches [190030] (2 species)
    not a true protein

    1. Species Human (Homo sapiens) [TaxId:9606] [187366] (4 PDB entries)

    2. Species Mouse (Mus musculus) [TaxId:10090] [346690] (1 PDB entry)

More info for Family a.60.1.2: SAM (sterile alpha motif) domain

Timeline for Family a.60.1.2: SAM (sterile alpha motif) domain:

• Family a.60.1.2: SAM (sterile alpha motif) domain first appeared (with stable ids) in SCOP 1.55
  
• Family a.60.1.2: SAM (sterile alpha motif) domain appears in SCOPe 2.07