SCOPe 2.01: Family a.60.1.1: Pointed domain

Lineage for Family a.60.1.1: Pointed domain

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.60: SAM domain-like [47768] (16 superfamilies)
   4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

4. Superfamily a.60.1: SAM/Pointed domain [47769] (4 families)

5. Family a.60.1.1: Pointed domain [47770] (6 proteins)

Proteins:

1. Ets DNA-binding protein pokkuri (Yan) [109863] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [109864] (2 PDB entries)
     Uniprot Q01842 42-118

2. Ets-1 transcription factor pointed domain [47771] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [47772] (1 PDB entry)

3. Etv6 transcription factor pointed domain (Tel SAM) [74735] (2 species)

   1. Species Escherichia coli [TaxId:562] [158525] (3 PDB entries)

   2. Species Human (Homo sapiens) [TaxId:9606] [74736] (2 PDB entries)

4. GABP-alpha subunit [109867] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [109868] (1 PDB entry)
     Uniprot Q00422 168-254 # structure of the Ets domain (320-429) is also known (46868)

5. Modulator of the activity of Ets (MAE, CG15085-PA) [109865] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [109866] (1 PDB entry)
     Uniprot Q9I7G2 94-173

6. Transcriptional regulator ERG [109869] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [109870] (1 PDB entry)
     Uniprot P11308 115-208

More info for Family a.60.1.1: Pointed domain

Timeline for Family a.60.1.1: Pointed domain:

• Family a.60.1.1: Pointed domain first appeared (with stable ids) in SCOP 1.55
  
• Family a.60.1.1: Pointed domain appears in SCOP 1.75
  
• Family a.60.1.1: Pointed domain appears in SCOPe 2.02
  
• Family a.60.1.1: Pointed domain appears in the current release, SCOPe 2.08