Class a: All alpha proteins [46456] (284 folds) |
Fold a.43: Ribbon-helix-helix [47597] (1 superfamily) core: 4 helices; array of 2 hairpins, opened |
Superfamily a.43.1: Ribbon-helix-helix [47598] (11 families) formerly Met repressor-like; dimeric proteins; the N-termini form a small beta-sheet ribbon |
a.43.1.1: Arc/Mnt-like phage repressors [47599] (2 proteins) |
a.43.1.3: CopG-like [100970] (4 proteins) similar to the phage repressor family |
a.43.1.4: Omega transcriptional repressor [100971] (2 proteins) plasmid-encoded, similar to the phage repressor family |
a.43.1.5: Met repressor, MetJ (MetR) [100972] (1 protein) |
a.43.1.6: NE0241-like [140544] (1 protein) contains extra C-terminal long helix; currently consists of an orphan protein |
a.43.1.7: SeqA N-terminal domain-like [140547] (1 protein) N-terminal part of Pfam PF03925 |
a.43.1.8: Trafficking protein A-like [140550] (1 protein) |
a.43.1.9: VCA0319-like [140553] (1 protein) COG4453; extended and extra C-terminal helices; potential component of the bi-partite system also including an acetyltransferase |
a.43.1.10: VirC2-like [158482] (1 protein) Pfam PF07181; duplicated ribbon-helix-helix motif; fold forms a trefoil knot |
a.43.1.11: PutA pre-N-terminal region-like [158485] (2 proteins) in PutA it forms a separate ribbon-helix-helix domain connected to the N-terminal enzymatic domain by a flexible linker |
a.43.1.12: MJ0366-like [158488] (1 protein) PfamB PB022101; duplicated ribbon-helix-helix motif; forms trefoil knot; predicted DNA binding |
Timeline for Superfamily a.43.1: Ribbon-helix-helix: