Class a: All alpha proteins [46456] (284 folds) |
Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily) core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets duplication: consists of two structural repeats |
Superfamily a.42.1: SWIB/MDM2 domain [47592] (1 family) binds to the transactivation domain of human p53 |
Family a.42.1.1: SWIB/MDM2 domain [47593] (4 proteins) Pfam PF02201 |
Protein MDM2 [47594] (2 species) |
Species Human (Homo sapiens) [TaxId:9606] [47596] (6 PDB entries) |
Domain d1rv1a_: 1rv1 A: [97901] |
Domain d1rv1b_: 1rv1 B: [97902] |
Domain d1rv1c_: 1rv1 C: [97903] complexed with imz; mutant |
Domain d1t4ea1: 1t4e A:25-109 [119142] automatically matched to d1ycra_ complexed with diz; mutant |
Domain d1t4eb1: 1t4e B:25-109 [119143] automatically matched to d1ycra_ complexed with diz; mutant |
Domain d1t4fm1: 1t4f M:25-109 [119144] automatically matched to d1ycra_ complexed with so4; mutant |
Domain d1ycra_: 1ycr A: [17420] |
Domain d2axia1: 2axi A:25-109 [127494] automatically matched to d1ycra_ complexed with 6cw, mpo, so4 |
Domain d2gv2a1: 2gv2 A:25-109 [135756] automatically matched to d1ycra_ complexed with 1ac, 6cw, ace, pm3 |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.42.1.1 MDM2: