Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOP 1.75
  2. 758332Class a: All alpha proteins [46456] (284 folds)
  3. 769486Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 769487Superfamily a.42.1: SWIB/MDM2 domain [47592] (1 family) (S)
    binds to the transactivation domain of human p53
  5. 769488Family a.42.1.1: SWIB/MDM2 domain [47593] (4 proteins)
    Pfam PF02201
  6. 769495Protein MDM2 [47594] (2 species)
  7. 769499Species Human (Homo sapiens) [TaxId:9606] [47596] (6 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1rv1:
    1. 769503Domain d1rv1a_: 1rv1 A: [97901]
    2. 769504Domain d1rv1b_: 1rv1 B: [97902]
    3. 769505Domain d1rv1c_: 1rv1 C: [97903]
      complexed with imz; mutant
  2. Domain(s) for 1t4e:
    1. 769507Domain d1t4ea1: 1t4e A:25-109 [119142]
      automatically matched to d1ycra_
      complexed with diz; mutant
    2. 769508Domain d1t4eb1: 1t4e B:25-109 [119143]
      automatically matched to d1ycra_
      complexed with diz; mutant
  3. Domain(s) for 1t4f:
  4. Domain(s) for 1ycr:
  5. Domain(s) for 2axi:
  6. Domain(s) for 2gv2:

More info for Species Human (Homo sapiens) [TaxId:9606] from a.42.1.1 MDM2

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.42.1.1 MDM2: