Lineage for Protein: MDM2

  1. Root: SCOPe 2.03
  2. 1253684Class a: All alpha proteins [46456] (284 folds)
  3. 1270168Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 1270169Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 1270170Family a.42.1.1: SWIB/MDM2 domain [47593] (4 proteins)
    Pfam PF02201
  6. 1270177Protein MDM2 [47594] (2 species)

Species:

  1. 1270178African clawed frog (Xenopus laevis) [TaxId:8355] [47595] (9 PDB entries)
    Uniprot P56273 13-119
    1. Domain for 1ttv:
    2. Domain for 1ycq:
    3. Domain for 4ipf:
    4. Domain for 4j3e:
    5. Domain for 4j74:
    6. Domain for 4j7d:
    7. Domain for 4j7e:
    8. Domains for 4jrg:
      1. 1270184Domain d4jrga_: 4jrg A: [223955]
        automated match to d1ycqa_
        complexed with i09
      2. 1270185Domain d4jrgb_: 4jrg B: [223956]
        automated match to d1ycqa_
        complexed with i09
    9. Domains for 4jsc:
      1. 1270187Domain d4jsca_: 4jsc A: [223976]
        automated match to d1ycqa_
        complexed with 1oy
      2. 1270188Domain d4jscb_: 4jsc B: [223977]
        automated match to d1ycqa_
        complexed with 1oy
  2. 1270190Human (Homo sapiens) [TaxId:9606] [47596] (36 PDB entries)
    1. Domains for 1rv1:
      1. 1270244Domain d1rv1a_: 1rv1 A: [97901]
        complexed with imz
      2. 1270245Domain d1rv1b_: 1rv1 B: [97902]
        complexed with imz
      3. 1270246Domain d1rv1c_: 1rv1 C: [97903]
        complexed with imz
    2. Domains for 1t4e:
      1. 1270250Domain d1t4ea_: 1t4e A: [119142]
        automated match to d1rv1a_
        complexed with diz
      2. 1270251Domain d1t4eb_: 1t4e B: [119143]
        automated match to d1rv1a_
        complexed with diz
    3. Domain for 1t4f:
    4. Domain for 1ycr:
    5. Domain for 2axi:
    6. Domain for 2gv2:
    7. Domains for 3g03:
      1. 1270204Domain d3g03a_: 3g03 A: [176230]
        automated match to d1rv1a_
      2. 1270205Domain d3g03c_: 3g03 C: [176231]
        automated match to d1rv1a_
    8. Domain for 3jzk:
    9. Domain for 3jzr:
    10. Domain for 3jzs:
    11. Domain for 3lbk:
    12. Domains for 3lbl:
      1. 1270193Domain d3lbla_: 3lbl A: [180164]
        automated match to d1rv1a_
        complexed with mi6
      2. 1270194Domain d3lblc_: 3lbl C: [180165]
        automated match to d1rv1a_
        complexed with mi6
      3. 1270195Domain d3lble_: 3lbl E: [180166]
        automated match to d1rv1a_
        complexed with mi6
    13. Domains for 3tj2:
      1. 1270236Domain d3tj2a_: 3tj2 A: [192477]
        automated match to d1t4ea_
        protein/DNA complex; complexed with k, tj2
      2. 1270237Domain d3tj2c_: 3tj2 C: [192476]
        automated match to d1t4ea_
        protein/DNA complex; complexed with k, tj2
    14. Domain for 3tu1:
    15. Domains for 3v3b:
      1. 1270201Domain d3v3ba_: 3v3b A: [186458]
        automated match to d1rv1a_
        protein/DNA complex; complexed with cl
      2. 1270202Domain d3v3bb_: 3v3b B: [186459]
        automated match to d1rv1a_
        protein/DNA complex; complexed with cl
    16. Domains for 3vbg:
      1. 1270257Domain d3vbga_: 3vbg A: [195030]
        automated match to d1rv1a_
        complexed with 03m
      2. 1270258Domain d3vbgb_: 3vbg B: [201219]
        automated match to d1rv1a_
        complexed with 03m
      3. 1270259Domain d3vbgc_: 3vbg C: [195029]
        automated match to d1rv1a_
        complexed with 03m
      4. 1270260Domain d3vbgd_: 3vbg D: [195031]
        automated match to d1rv1a_
        complexed with 03m
    17. Domains for 3vzv:
      1. 1270261Domain d3vzva_: 3vzv A: [201266]
        automated match to d3vzvb_
        complexed with vzv
      2. 1270262Domain d3vzvb_: 3vzv B: [193259]
        automated match to d1rv1a_
        complexed with vzv
    18. Domains for 3w69:
      1. 1270206Domain d3w69a_: 3w69 A: [197281]
        automated match to d1rv1a_
        complexed with ltz, so4
      2. 1270207Domain d3w69b_: 3w69 B: [201283]
        automated match to d3vzvb_
        complexed with ltz, so4
    19. Domains for 4dij:
      1. 1270199Domain d4dija_: 4dij A: [195473]
        automated match to d3jzra_
        complexed with blf
      2. 1270200Domain d4dijb_: 4dij B: [195472]
        automated match to d3jzra_
        complexed with blf
    20. Domains for 4ere:
      1. 1270222Domain d4erea_: 4ere A: [192401]
        automated match to d1t4ea_
        complexed with 0r2, so4
      2. 1270223Domain d4ereb_: 4ere B: [192402]
        automated match to d1t4ea_
        complexed with 0r2, so4
    21. Domains for 4erf:
      1. 1270233Domain d4erfa_: 4erf A: [192403]
        automated match to d1t4ea_
        complexed with 0r3
      2. 1270234Domain d4erfc_: 4erf C: [192404]
        automated match to d1t4ea_
        complexed with 0r3
      3. 1270235Domain d4erfe_: 4erf E: [192405]
        automated match to d1t4ea_
        complexed with 0r3
    22. Domains for 4hbm:
      1. 1270214Domain d4hbma_: 4hbm A: [202405]
        automated match to d4hbme_
        complexed with 0y7
      2. 1270215Domain d4hbmb_: 4hbm B: [202406]
        automated match to d4hbme_
        complexed with 0y7
      3. 1270216Domain d4hbmc_: 4hbm C: [202407]
        automated match to d4hbme_
        complexed with 0y7
      4. 1270217Domain d4hbmd_: 4hbm D: [202408]
        automated match to d4hbme_
        complexed with 0y7
      5. 1270218Domain d4hbme_: 4hbm E: [193444]
        automated match to d3jzra_
        complexed with 0y7
      6. 1270219Domain d4hbmf_: 4hbm F: [202409]
        automated match to d4hbme_
        complexed with 0y7
      7. 1270220Domain d4hbmg_: 4hbm G: [202410]
        automated match to d4hbme_
        complexed with 0y7
      8. 1270221Domain d4hbmh_: 4hbm H: [202411]
        automated match to d4hbme_
        complexed with 0y7
    23. Domain for 4hg7:
    24. Domain for 4jv7:
    25. Domain for 4jv9:
    26. Domain for 4jve:
    27. Domains for 4jvr:
      1. 1270208Domain d4jvra_: 4jvr A: [196976]
        automated match to d4ereb_
        complexed with 1mt
      2. 1270209Domain d4jvrc_: 4jvr C: [202809]
        automated match to d4jvra_
        complexed with 1mt
      3. 1270210Domain d4jvre_: 4jvr E: [202810]
        automated match to d4jvra_
        complexed with 1mt
    28. Domains for 4jwr:
      1. 1270241Domain d4jwra_: 4jwr A: [197258]
        automated match to d4ereb_
        complexed with 1my
      2. 1270242Domain d4jwrb_: 4jwr B: [196977]
        automated match to d4ereb_
        complexed with 1my
      3. 1270243Domain d4jwrc_: 4jwr C: [202812]
        automated match to d4jwrb_
        complexed with 1my
    29. Domain for 4mdn:
    30. Domain for 4mdq:
    31. Domains for 4oas:
      1. 1270211Domain d4oasa_: 4oas A: [237088]
        automated match to d1t4ea_
        complexed with 2sw, so4
      2. 1270212Domain d4oasc_: 4oas C: [237089]
        automated match to d1t4ea_
        complexed with 2sw, so4
      3. 1270213Domain d4oase_: 4oas E: [237087]
        automated match to d1t4ea_
        complexed with 2sw, so4
    32. Domains for 4oba:
      1. 1270230Domain d4obaa_: 4oba A: [237866]
        automated match to d1t4ea_
        complexed with 2tw
      2. 1270231Domain d4obab_: 4oba B: [237867]
        automated match to d1t4ea_
        complexed with 2tw
      3. 1270232Domain d4obac_: 4oba C: [237868]
        automated match to d1t4ea_
        complexed with 2tw
    33. Domains for 4occ:
      1. 1270227Domain d4occa_: 4occ A: [238273]
        automated match to d1t4ea_
        complexed with 2tz
      2. 1270228Domain d4occc_: 4occ C: [238272]
        automated match to d1t4ea_
        complexed with 2tz
      3. 1270229Domain d4occe_: 4occ E: [238274]
        automated match to d1t4ea_
        complexed with 2tz
    34. Domain for 4ode:
    35. Domain for 4odf:
    36. Domains for 4ogv:
      1. 1270253Domain d4ogva_: 4ogv A: [238277]
        automated match to d4jwra_
        complexed with 2u7
      2. 1270254Domain d4ogvb_: 4ogv B: [238278]
        automated match to d4jwra_
        complexed with 2u7
      3. 1270255Domain d4ogvc_: 4ogv C: [238279]
        automated match to d4jwra_
        complexed with 2u7

More info for Protein MDM2 from a.42.1.1: SWIB/MDM2 domain

Timeline for Protein MDM2 from a.42.1.1: SWIB/MDM2 domain: