Lineage for Protein: MDM2

  1. Root: SCOPe 2.01
  2. 901761Class a: All alpha proteins [46456] (284 folds)
  3. 915347Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 915348Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 915349Family a.42.1.1: SWIB/MDM2 domain [47593] (4 proteins)
    Pfam PF02201
  6. 915356Protein MDM2 [47594] (2 species)

Species:

  1. 915357African clawed frog (Xenopus laevis) [TaxId:8355] [47595] (2 PDB entries)
    Uniprot P56273 13-119
    1. Domain for 1ttv:
    2. Domain for 1ycq:
  2. 915360Human (Homo sapiens) [TaxId:9606] [47596] (14 PDB entries)
    1. Domains for 1rv1:
      1. 915375Domain d1rv1a_: 1rv1 A: [97901]
        complexed with imz
      2. 915376Domain d1rv1b_: 1rv1 B: [97902]
        complexed with imz
      3. 915377Domain d1rv1c_: 1rv1 C: [97903]
        complexed with imz
    2. Domains for 1t4e:
      1. 915380Domain d1t4ea_: 1t4e A: [119142]
        automated match to d1rv1a_
        complexed with diz
      2. 915381Domain d1t4eb_: 1t4e B: [119143]
        automated match to d1rv1a_
        complexed with diz
    3. Domain for 1t4f:
    4. Domain for 1ycr:
    5. Domain for 2axi:
    6. Domain for 2gv2:
    7. Domains for 3g03:
      1. 915371Domain d3g03a_: 3g03 A: [176230]
        automated match to d1rv1a_
      2. 915372Domain d3g03c_: 3g03 C: [176231]
        automated match to d1rv1a_
    8. Domain for 3jzk:
    9. Domain for 3jzr:
    10. Domain for 3jzs:
    11. Domain for 3lbk:
    12. Domains for 3lbl:
      1. 915362Domain d3lbla_: 3lbl A: [180164]
        automated match to d1rv1a_
        complexed with mi6
      2. 915363Domain d3lblc_: 3lbl C: [180165]
        automated match to d1rv1a_
        complexed with mi6
      3. 915364Domain d3lble_: 3lbl E: [180166]
        automated match to d1rv1a_
        complexed with mi6
    13. Domain for 3tu1:
    14. Domains for 3v3b:
      1. 915368Domain d3v3ba_: 3v3b A: [186458]
        automated match to d1rv1a_
        protein/DNA complex; complexed with cl
      2. 915369Domain d3v3bb_: 3v3b B: [186459]
        automated match to d1rv1a_
        protein/DNA complex; complexed with cl

More info for Protein MDM2 from a.42.1.1: SWIB/MDM2 domain

Timeline for Protein MDM2 from a.42.1.1: SWIB/MDM2 domain: