Lineage for Protein: MDM2

  1. Root: SCOP 1.73
  2. 631650Class a: All alpha proteins [46456] (258 folds)
  3. 641571Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 641572Superfamily a.42.1: SWIB/MDM2 domain [47592] (1 family) (S)
    binds to the transactivation domain of human p53
  5. 641573Family a.42.1.1: SWIB/MDM2 domain [47593] (4 proteins)
    Pfam PF02201
  6. 641580Protein MDM2 [47594] (2 species)

Species:

  1. 641581African clawed frog (Xenopus laevis) [TaxId:8355] [47595] (2 PDB entries)
    1. Domain for 1ttv:
    2. Domain for 1ycq:
  2. 641584Human (Homo sapiens) [TaxId:9606] [47596] (6 PDB entries)
    1. Domains for 1rv1:
      1. 641588Domain d1rv1a_: 1rv1 A: [97901]
      2. 641589Domain d1rv1b_: 1rv1 B: [97902]
      3. 641590Domain d1rv1c_: 1rv1 C: [97903]
        complexed with imz; mutant
    2. Domains for 1t4e:
      1. 641592Domain d1t4ea1: 1t4e A:25-109 [119142]
        automatically matched to d1ycra_
        complexed with diz; mutant
      2. 641593Domain d1t4eb1: 1t4e B:25-109 [119143]
        automatically matched to d1ycra_
        complexed with diz; mutant
    3. Domain for 1t4f:
    4. Domain for 1ycr:
    5. Domain for 2axi:
    6. Domain for 2gv2:

More info for Protein MDM2 from a.42.1.1: SWIB/MDM2 domain

Timeline for Protein MDM2 from a.42.1.1: SWIB/MDM2 domain: