Lineage for Protein: MDM2

  1. Root: SCOP 1.67
  2. 349259Class a: All alpha proteins [46456] (202 folds)
  3. 355856Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 355857Superfamily a.42.1: SWIB/MDM2 domain [47592] (1 family) (S)
    binds to the transactivation domain of human p53
  5. 355858Family a.42.1.1: SWIB/MDM2 domain [47593] (3 proteins)
    Pfam 02201
  6. 355865Protein MDM2 [47594] (2 species)

Species:

  1. 355866African clawed frog (Xenopus laevis) [TaxId:8355] [47595] (1 PDB entry)
  2. 355868Human (Homo sapiens) [TaxId:9606] [47596] (2 PDB entries)
    1. Domains for 1rv1:
      1. 355869Domain d1rv1a_: 1rv1 A: [97901]
      2. 355870Domain d1rv1b_: 1rv1 B: [97902]
      3. 355871Domain d1rv1c_: 1rv1 C: [97903]
        complexed with imz; mutant
    2. Domain for 1ycr:

More info for Protein MDM2 from a.42.1.1: SWIB/MDM2 domain

Timeline for Protein MDM2 from a.42.1.1: SWIB/MDM2 domain: