SCOPe 2.02: Superfamily a.42.1: SWIB/MDM2 domain

Lineage for Superfamily a.42.1: SWIB/MDM2 domain

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
   core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
   duplication: consists of two structural repeats

4. Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families)
   binds to the transactivation domain of human p53

Families:

1. a.42.1.1: SWIB/MDM2 domain [47593] (4 proteins)
   Pfam PF02201

2. a.42.1.0: automated matches [191556] (1 protein)
   not a true family

More info for Superfamily a.42.1: SWIB/MDM2 domain

Timeline for Superfamily a.42.1: SWIB/MDM2 domain:

• Superfamily a.42.1: SWIB/MDM2 domain first appeared (with stable ids) in SCOP 1.55, called Superfamily a.42.1: MDM2
  
• Superfamily a.42.1: SWIB/MDM2 domain appears in SCOPe 2.01
  
• Superfamily a.42.1: SWIB/MDM2 domain appears in SCOPe 2.03
  
• Superfamily a.42.1: SWIB/MDM2 domain appears in the current release, SCOPe 2.08