SCOPe 2.07: Family a.40.1.1: Calponin-homology domain, CH-domain

Lineage for Family a.40.1.1: Calponin-homology domain, CH-domain

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.40: CH domain-like [47575] (3 superfamilies)
   core: 4 helices: bundle

4. Superfamily a.40.1: Calponin-homology domain, CH-domain [47576] (2 families)

5. Family a.40.1.1: Calponin-homology domain, CH-domain [47577] (10 proteins)
   Pfam PF00307

Proteins:

1. Actin binding domain of plectin [89056] (1 species)
   duplication: consists of tandem repeat of two CH domains

   • Species Human (Homo sapiens) [TaxId:9606] [89057] (3 PDB entries)
     Uniprot Q9QXS1 182-411

2. beta-spectrin [47578] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [47579] (2 PDB entries)

3. Calponin [69029] (1 species)

   • Species Chicken (Gallus gallus) [TaxId:9031] [69030] (1 PDB entry)

4. Dystrophin [47584] (1 species)
   duplication: consists of tandem repeat of two CH domains

   • Species Human (Homo sapiens) [TaxId:9606] [47585] (1 PDB entry)

5. Fimbrin (Plastin), actin-crosslinking domain [47580] (3 species)
   duplication: tandem repeat of four CH domains

   1. Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [109828] (1 PDB entry)
      Uniprot O59945 108-614

   2. Species Human (Homo sapiens) [TaxId:9606] [47581] (2 PDB entries)
      Uniprot P13797 121-375, 517-627

   3. Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [109827] (1 PDB entry)
      Uniprot Q7G188 123-623

6. Microtubule-associated protein eb1, N-terminal microtubule binding domain [101194] (2 species)
   member of rp/eb family

   1. Species Human (Homo sapiens) [TaxId:9606] [101195] (5 PDB entries)
      Uniprot Q15691 2-132

   2. Species Mouse (Mus musculus) [TaxId:10090] [109829] (1 PDB entry)
      Uniprot Q61166 16-116

7. Ras GTPase-activating-like protein rng2 [101196] (1 species)

   • Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [101197] (2 PDB entries)
     Uniprot O14188 32-190

8. Transgelin [109830] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [109831] (1 PDB entry)
     Uniprot P37804 23-153

9. Utrophin [47582] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [47583] (2 PDB entries)

10. automated matches [191021] (2 species)
    not a true protein

    1. Species Human (Homo sapiens) [TaxId:9606] [188812] (7 PDB entries)

    2. Species Mouse (Mus musculus) [TaxId:10090] [258314] (1 PDB entry)

More info for Family a.40.1.1: Calponin-homology domain, CH-domain

Timeline for Family a.40.1.1: Calponin-homology domain, CH-domain:

• Family a.40.1.1: Calponin-homology domain, CH-domain first appeared (with stable ids) in SCOP 1.55
  
• Family a.40.1.1: Calponin-homology domain, CH-domain appears in SCOPe 2.06
  
• Family a.40.1.1: Calponin-homology domain, CH-domain appears in the current release, SCOPe 2.08