SCOP 1.69: Protein: Calmodulin

Lineage for Protein: Calmodulin

Root: SCOP 1.69
Class a: All alpha proteins [46456] (218 folds)
Fold a.39: EF Hand-like [47472] (4 superfamilies)
core: 4 helices; array of 2 hairpins, opened
Superfamily a.39.1: EF-hand [47473] (10 families)
Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
Family a.39.1.5: Calmodulin-like [47502] (23 proteins)
Duplication: made with two pairs of EF-hands
Protein Calmodulin [47516] (10 species)

Species:

African frog (Xenopus laevis) [TaxId:8355] [47521] (10 PDB entries)
1. Domain for 1cfc:
  - Domain d1cfc__: 1cfc - [17290]
2. Domain for 1cfd:
  - Domain d1cfd__: 1cfd - [17291]
3. Domain for 1cff:
  - Domain d1cffa_: 1cff A: [17295]
    complex with a binding peptide of the human Ca2+-pump
4. Domain for 1ckk:
  - Domain d1ckka_: 1ckk A: [17294]
    complex with a fragment of the rat ca2+/calmodulin dependent protein kinase
5. Domain for 1dmo:
  - Domain d1dmo__: 1dmo - [17293]
6. Domain for 1f70:
  - Domain d1f70a_: 1f70 A: [17288]
    N-terminal domain
7. Domain for 1f71:
  - Domain d1f71a_: 1f71 A: [17289]
    C-terminal domain
8. Domain for 1iq5:
  - Domain d1iq5a_: 1iq5 A: [62643]
    complex with a ca2+/calmodulin dependent kinase kinase fragment
9. Domain for 1mux:
  - Domain d1mux__: 1mux - [17292]
10. Domain for 1nwd:
  - Domain d1nwda_: 1nwd A: [86297]
    complex with the C-terminal fragment of glutamate decarboxylase, chains B and C
Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89052] (3 PDB entries)
1. Domain for 1f54:
  - Domain d1f54a_: 1f54 A: [83244]
    N-terminal domain, apo form
2. Domain for 1f55:
  - Domain d1f55a_: 1f55 A: [83245]
    N-terminal domain, calcium bound form
3. Domain for 1lkj:
  - Domain d1lkja_: 1lkj A: [84623]
Chicken (Gallus gallus) [TaxId:9031] [47520] (1 PDB entry)
mutant with a two residue deletion in the central helix
- Domain for 1ahr:
  - Domain d1ahr__: 1ahr - [17287]
Ciliate (Paramecium tetraurelia) [TaxId:5888] [47523] (4 PDB entries)
1. Domain for 1clm:
  - Domain d1clm__: 1clm - [17301]
2. Domain for 1exr:
  - Domain d1exra_: 1exr A: [17299]
3. Domains for 1n0y:
  1. Domain d1n0ya_: 1n0y A: [91536]
  2. Domain d1n0yb_: 1n0y B: [91537]
4. Domain for 1osa:
  - Domain d1osa__: 1osa - [17300]
Cow (Bos taurus) [TaxId:9913] [47518] (16 PDB entries)
1. Domain for 1a29:
  - Domain d1a29__: 1a29 - [17276]
    trifluoperazine 1:2 complex
2. Domain for 1ak8:
  - Domain d1ak8__: 1ak8 - [17281]
    N-terminal domain
3. Domains for 1cdl:
  1. Domain d1cdla_: 1cdl A: [17272]
  2. Domain d1cdlb_: 1cdl B: [17273]
  3. Domain d1cdlc_: 1cdl C: [17274]
  4. Domain d1cdld_: 1cdl D: [17275]
    complexed with calmodulin-binding peptide from smooth muscle myosin light chain kinase
4. Domain for 1cdm:
  - Domain d1cdma_: 1cdm A: [17270]
    complexed with calmodulin-binding domain of calmodulin-dependent protein kinase
5. Domain for 1cm1:
  - Domain d1cm1a_: 1cm1 A: [17271]
6. Domains for 1cm4:
  1. Domain d1cm4a_: 1cm4 A: [17266]
  2. Domain d1cm4c_: 1cm4 C: [17267]
  3. Domain d1cm4e_: 1cm4 E: [17268]
  4. Domain d1cm4g_: 1cm4 G: [17269]
7. Domain for 1cmf:
  - Domain d1cmf__: 1cmf - [17283]
    C-terminal domain in apo form
8. Domain for 1cmg:
  - Domain d1cmg__: 1cmg - [17282]
    C-terminal domain in calcium-loaded form
9. Domain for 1deg:
  - Domain d1deg__: 1deg - [17280]
    mutant, E84 deleted
10. Domain for 1fw4:
  - Domain d1fw4a_: 1fw4 A: [60056]
    C-terminal domain
11. Domain for 1j7o:
  - Domain d1j7oa_: 1j7o A: [66415]
    N-terminal domain
12. Domain for 1j7p:
  - Domain d1j7pa_: 1j7p A: [66416]
    C-terminal domain
13. Domain for 1lin:
  - Domain d1lin__: 1lin - [17265]
14. Domain for 1prw:
  - Domain d1prwa_: 1prw A: [95062]
15. Domain for 1qiv:
  - Domain d1qiva_: 1qiv A: [17279]
16. Domains for 1qiw:
  1. Domain d1qiwa_: 1qiw A: [17277]
  2. Domain d1qiwb_: 1qiw B: [17278]
Drosophila melanogaster [TaxId:7227] [47522] (4 PDB entries)
1. Domains for 1mxe:
  1. Domain d1mxea_: 1mxe A: [79644]
  2. Domain d1mxeb_: 1mxe B: [79645]
    complex with the target sequence of Calmodulin-dependent protein kinase I (1a06), chains E and F
2. Domain for 2bbm:
  - Domain d2bbma_: 2bbm A: [17297]
3. Domain for 2bbn:
  - Domain d2bbna_: 2bbn A: [17298]
4. Domain for 4cln:
  - Domain d4cln__: 4cln - [17296]
Human (Homo sapiens) [TaxId:9606] [47517] (11 PDB entries)
1. Domain for 1cll:
  - Domain d1cll__: 1cll - [17263]
2. Domain for 1ctr:
  - Domain d1ctr__: 1ctr - [17264]
    trifluoperazine 1:1 complex
3. Domain for 1iwq:
  - Domain d1iwqa_: 1iwq A: [83761]
    complexed with Marcks calmodulin binding domain peptide, chain B
4. Domains for 1k90:
  1. Domain d1k90d_: 1k90 D: [68322]
    Other proteins in same PDB: d1k90a_, d1k90b_, d1k90c_
  2. Domain d1k90e_: 1k90 E: [68323]
    Other proteins in same PDB: d1k90a_, d1k90b_, d1k90c_
  3. Domain d1k90f_: 1k90 F: [68324]
    Other proteins in same PDB: d1k90a_, d1k90b_, d1k90c_
5. Domains for 1k93:
  1. Domain d1k93d_: 1k93 D: [68330]
    Other proteins in same PDB: d1k93a_, d1k93b_, d1k93c_
  2. Domain d1k93e_: 1k93 E: [68331]
    Other proteins in same PDB: d1k93a_, d1k93b_, d1k93c_
  3. Domain d1k93f_: 1k93 F: [68332]
    Other proteins in same PDB: d1k93a_, d1k93b_, d1k93c_
6. Domain for 1l7z:
  - Domain d1l7za_: 1l7z A: [91054]
    complexed with a myristoylated peptide, chain B
7. Domains for 1lvc:
  1. Domain d1lvcd_: 1lvc D: [78239]
    Other proteins in same PDB: d1lvca_, d1lvcb_, d1lvcc_
  2. Domain d1lvce_: 1lvc E: [78240]
    Other proteins in same PDB: d1lvca_, d1lvcb_, d1lvcc_
  3. Domain d1lvcf_: 1lvc F: [78241]
    Other proteins in same PDB: d1lvca_, d1lvcb_, d1lvcc_
8. Domains for 1pk0:
  1. Domain d1pk0d_: 1pk0 D: [94798]
    Other proteins in same PDB: d1pk0a_, d1pk0b_, d1pk0c_
  2. Domain d1pk0e_: 1pk0 E: [94799]
    Other proteins in same PDB: d1pk0a_, d1pk0b_, d1pk0c_
  3. Domain d1pk0f_: 1pk0 F: [94800]
    Other proteins in same PDB: d1pk0a_, d1pk0b_, d1pk0c_
9. Domains for 1s26:
  1. Domain d1s26d_: 1s26 D: [98370]
    Other proteins in same PDB: d1s26a_, d1s26b_, d1s26c_
  2. Domain d1s26e_: 1s26 E: [98371]
    Other proteins in same PDB: d1s26a_, d1s26b_, d1s26c_
  3. Domain d1s26f_: 1s26 F: [98372]
    Other proteins in same PDB: d1s26a_, d1s26b_, d1s26c_
10. Domains for 1sk6:
  1. Domain d1sk6d_: 1sk6 D: [105668]
    Other proteins in same PDB: d1sk6a_, d1sk6b_, d1sk6c_
  2. Domain d1sk6e_: 1sk6 E: [105669]
    Other proteins in same PDB: d1sk6a_, d1sk6b_, d1sk6c_
  3. Domain d1sk6f_: 1sk6 F: [105670]
    Other proteins in same PDB: d1sk6a_, d1sk6b_, d1sk6c_
11. Domain for 1sw8:
  - Domain d1sw8a_: 1sw8 A: [99022]
    N-terminal domain only
Nematode (Caenorhabditis elegans) [TaxId:6239] [89051] (1 PDB entry)
- Domain for 1ooj:
  - Domain d1ooja_: 1ooj A: [87198]
    structural genomics
Potato (Solanum tuberosum) [TaxId:4113] [109820] (1 PDB entry)
- Domain for 1rfj:
  - Domain d1rfja_: 1rfj A: [104918]
Rat (Rattus rattus) [TaxId:10117] [47519] (5 PDB entries)
1. Domain for 1g4y:
  - Domain d1g4yr_: 1g4y R: [60252]
    Other proteins in same PDB: d1g4yb_
2. Domains for 1niw:
  1. Domain d1niwa_: 1niw A: [80537]
  2. Domain d1niwc_: 1niw C: [80538]
  3. Domain d1niwe_: 1niw E: [80539]
  4. Domain d1niwg_: 1niw G: [80540]
    complexed with an endothelial nitric oxide synthase peptide, chains B, D, F and H
3. Domains for 1qx5:
  1. Domain d1qx5b_: 1qx5 B: [104628]
  2. Domain d1qx5d_: 1qx5 D: [104629]
  3. Domain d1qx5i_: 1qx5 I: [104630]
  4. Domain d1qx5j_: 1qx5 J: [104631]
  5. Domain d1qx5k_: 1qx5 K: [104632]
  6. Domain d1qx5r_: 1qx5 R: [104633]
  7. Domain d1qx5t_: 1qx5 T: [104634]
  8. Domain d1qx5y_: 1qx5 Y: [104635]
    apocalmodulin; oligomer with swapped EF-hand units
4. Domains for 1qx7:
  1. Domain d1qx7a_: 1qx7 A: [104636]
  2. Domain d1qx7b_: 1qx7 B: [104637]
  3. Domain d1qx7i_: 1qx7 I: [104638]
  4. Domain d1qx7m_: 1qx7 M: [104639]
  5. Domain d1qx7r_: 1qx7 R: [104640]
    apocalmodulin; oligomer with swapped EF-hand units
5. Domain for 3cln:
  - Domain d3cln__: 3cln - [17286]

More info for Protein Calmodulin from a.39.1.5: Calmodulin-like

Timeline for Protein Calmodulin from a.39.1.5: Calmodulin-like:

Protein Calmodulin from a.39.1.5: Calmodulin-like first appeared (with stable ids) in SCOP 1.55
Protein Calmodulin from a.39.1.5: Calmodulin-like appears in SCOP 1.67
Protein Calmodulin from a.39.1.5: Calmodulin-like appears in SCOP 1.71
Protein Calmodulin from a.39.1.5: Calmodulin-like appears in the current release, SCOPe 2.08