Lineage for Protein: Calmodulin

  1. Root: SCOP 1.63
  2. 208553Class a: All alpha proteins [46456] (171 folds)
  3. 213166Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 213167Superfamily a.39.1: EF-hand [47473] (9 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 213324Family a.39.1.5: Calmodulin-like [47502] (17 proteins)
    Duplication: made with two pairs of EF-hands
  6. 213352Protein Calmodulin [47516] (7 species)

Species:

  1. 213353African frog (Xenopus laevis) [TaxId:8355] [47521] (9 PDB entries)
    1. Domain for 1cfc:
    2. Domain for 1cfd:
    3. Domain for 1cff:
      • 213362Domain d1cffa_: 1cff A: [17295]
        complex with a binding peptide of the human Ca2+-pump
        complexed with ca
    4. Domain for 1ckk:
      • 213361Domain d1ckka_: 1ckk A: [17294]
        complex with a fragment of the rat ca2+/calmodulin dependent protein kinase
        complexed with ca
    5. Domain for 1dmo:
    6. Domain for 1f70:
    7. Domain for 1f71:
    8. Domain for 1iq5:
      • 213354Domain d1iq5a_: 1iq5 A: [62643]
        complex with a ca2+/calmodulin dependent kinase kinase fragment
        complexed with ca
    9. Domain for 1mux:
  2. 213363Chicken (Gallus gallus) [TaxId:9031] [47520] (1 PDB entry)
    mutant with a two residue deletion in the central helix
  3. 213365Ciliate (Paramecium tetraurelia) [TaxId:5888] [47523] (3 PDB entries)
    1. Domain for 1clm:
    2. Domain for 1exr:
    3. Domain for 1osa:
  4. 213369Cow (Bos taurus) [TaxId:9913] [47518] (15 PDB entries)
    1. Domain for 1a29:
      • 213382Domain d1a29__: 1a29 - [17276]
        trifluoperazine 1:2 complex
        complexed with ca, tfp
    2. Domain for 1ak8:
    3. Domains for 1cdl:
      1. 213378Domain d1cdla_: 1cdl A: [17272]
      2. 213379Domain d1cdlb_: 1cdl B: [17273]
      3. 213380Domain d1cdlc_: 1cdl C: [17274]
      4. 213381Domain d1cdld_: 1cdl D: [17275]
        complexed with calmodulin-binding peptide from smooth muscle myosin light chain kinase
        complexed with ca
    4. Domain for 1cdm:
      • 213376Domain d1cdma_: 1cdm A: [17270]
        complexed with calmodulin-binding domain of calmodulin-dependent protein kinase
        complexed with ca
    5. Domain for 1cm1:
    6. Domains for 1cm4:
      1. 213372Domain d1cm4a_: 1cm4 A: [17266]
      2. 213373Domain d1cm4c_: 1cm4 C: [17267]
      3. 213374Domain d1cm4e_: 1cm4 E: [17268]
      4. 213375Domain d1cm4g_: 1cm4 G: [17269]
        complexed with ca
    7. Domain for 1cmf:
    8. Domain for 1cmg:
    9. Domain for 1deg:
    10. Domain for 1fw4:
    11. Domain for 1j7o:
    12. Domain for 1j7p:
    13. Domain for 1lin:
    14. Domain for 1qiv:
    15. Domains for 1qiw:
      1. 213383Domain d1qiwa_: 1qiw A: [17277]
      2. 213384Domain d1qiwb_: 1qiw B: [17278]
        complexed with ca, dpd
  5. 213392Drosophila melanogaster [TaxId:7227] [47522] (4 PDB entries)
    1. Domains for 1mxe:
      1. 213393Domain d1mxea_: 1mxe A: [79644]
      2. 213394Domain d1mxeb_: 1mxe B: [79645]
        complex with the target sequence of Calmodulin-dependent protein kinase I (1a06), chains E and F
        complexed with ca
    2. Domain for 2bbm:
    3. Domain for 2bbn:
    4. Domain for 4cln:
  6. 213398Human (Homo sapiens) [TaxId:9606] [47517] (5 PDB entries)
    1. Domain for 1cll:
    2. Domain for 1ctr:
      • 213403Domain d1ctr__: 1ctr - [17264]
        trifluoperazine 1:1 complex
        complexed with ca, tfp
    3. Domains for 1k90:
      1. 213400Domain d1k90d_: 1k90 D: [68322]
        Other proteins in same PDB: d1k90a_, d1k90b_, d1k90c_
      2. 213401Domain d1k90e_: 1k90 E: [68323]
        Other proteins in same PDB: d1k90a_, d1k90b_, d1k90c_
      3. 213402Domain d1k90f_: 1k90 F: [68324]
        Other proteins in same PDB: d1k90a_, d1k90b_, d1k90c_
        complexed with 3at, ca, yb
    4. Domains for 1k93:
      1. 213404Domain d1k93d_: 1k93 D: [68330]
        Other proteins in same PDB: d1k93a_, d1k93b_, d1k93c_
      2. 213405Domain d1k93e_: 1k93 E: [68331]
        Other proteins in same PDB: d1k93a_, d1k93b_, d1k93c_
      3. 213406Domain d1k93f_: 1k93 F: [68332]
        Other proteins in same PDB: d1k93a_, d1k93b_, d1k93c_
        complexed with ca, so4
    5. Domains for 1lvc:
      1. 213407Domain d1lvcd_: 1lvc D: [78239]
        Other proteins in same PDB: d1lvca_, d1lvcb_, d1lvcc_
      2. 213408Domain d1lvce_: 1lvc E: [78240]
        Other proteins in same PDB: d1lvca_, d1lvcb_, d1lvcc_
      3. 213409Domain d1lvcf_: 1lvc F: [78241]
        Other proteins in same PDB: d1lvca_, d1lvcb_, d1lvcc_
        complexed with ca, dot, yb
  7. 213410Rat (Rattus rattus) [TaxId:10117] [47519] (3 PDB entries)
    1. Domain for 1g4y:
    2. Domains for 1niw:
      1. 213412Domain d1niwa_: 1niw A: [80537]
      2. 213413Domain d1niwc_: 1niw C: [80538]
      3. 213414Domain d1niwe_: 1niw E: [80539]
      4. 213415Domain d1niwg_: 1niw G: [80540]
        complexed with an endothelial nitric oxide synthase peptide, chains B, D, F and H
        complexed with ca, egl, mse, so4
    3. Domain for 3cln:

More info for Protein Calmodulin from a.39.1.5: Calmodulin-like

Timeline for Protein Calmodulin from a.39.1.5: Calmodulin-like: