Lineage for Protein: Troponin C

  1. Root: SCOP 1.67
  2. 349259Class a: All alpha proteins [46456] (202 folds)
  3. 355182Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 355183Superfamily a.39.1: EF-hand [47473] (10 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 355357Family a.39.1.5: Calmodulin-like [47502] (21 proteins)
    Duplication: made with two pairs of EF-hands
  6. 355570Protein Troponin C [47503] (5 species)

Species:

  1. 355571Chicken (Gallus gallus) [TaxId:9031] [47504] (24 PDB entries)
    1. Domain for 1aj4:
    2. Domains for 1avs:
      1. 355576Domain d1avsa_: 1avs A: [17226]
      2. 355577Domain d1avsb_: 1avs B: [17227]
        calcium-saturated N-terminal domain
        complexed with ca
    3. Domain for 1blq:
    4. Domains for 1cta:
      1. 355580Domain d1ctaa_: 1cta A: [17232]
      2. 355581Domain d1ctab_: 1cta B: [17233]
        fragment, corresponding to the 3rd EF-hand
        complexed with ca, nh2
    5. Domains for 1ctd:
      1. 355582Domain d1ctda_: 1ctd A: [17230]
      2. 355583Domain d1ctdb_: 1ctd B: [17231]
        fragment, corresponding to the 3rd EF-hand
        complexed with ca, nh2
    6. Domain for 1dtl:
    7. Domain for 1jc2:
    8. Domain for 1la0:
      • 355588Domain d1la0a_: 1la0 A: [77864]
        calcium saturated troponin C bound to troponin I
        complexed with ca
    9. Domain for 1ncx:
    10. Domain for 1ncy:
    11. Domain for 1ncz:
    12. Domain for 1npq:
      • 355594Domain d1npqa_: 1npq A: [85983]
        calcium saturated troponin C bound to troponin I fragment, chain B
        complexed with ca; mutant
    13. Domain for 1pon:
      • 355595Domain d1pon.1: 1pon A:,B: [17239]
        heterodimer of 3rd and 4th EF-hands
        complexed with ace, nh2
    14. Domain for 1skt:
    15. Domain for 1smg:
    16. Domain for 1tnp:
    17. Domain for 1tnq:
    18. Domain for 1tnw:
    19. Domain for 1tnx:
    20. Domain for 1top:
    21. Domain for 1zac:
    22. Domain for 2ctn:
      • 355598Domain d2ctn__: 2ctn - [17242]
        N-domain only; C-terminal domain is in 3CTN
        complexed with ca; mutant
    23. Domain for 3ctn:
      • 355591Domain d3ctn__: 3ctn - [17241]
        C-domain only; N-terminal domain is in 2CTN
        complexed with ca
    24. Domain for 4tnc:
  2. 355599Chicken (Gallus gallus), cardiac isoform [TaxId:9031] [47507] (1 PDB entry)
  3. 355601Human (Homo sapiens), cardiac isoform [TaxId:9606] [47508] (8 PDB entries)
    1. Domain for 1ap4:
    2. Domain for 1ih0:
    3. Domains for 1j1d:
      1. 355602Domain d1j1da_: 1j1d A: [83963]
        Other proteins in same PDB: d1j1db_, d1j1dc_, d1j1de_, d1j1df_
      2. 355603Domain d1j1dd_: 1j1d D: [83966]
        Other proteins in same PDB: d1j1db_, d1j1dc_, d1j1de_, d1j1df_
        complexed with ca; mutant
    4. Domains for 1j1e:
      1. 355604Domain d1j1ea_: 1j1e A: [83969]
        Other proteins in same PDB: d1j1eb_, d1j1ec_, d1j1ee_, d1j1ef_
      2. 355605Domain d1j1ed_: 1j1e D: [83972]
        Other proteins in same PDB: d1j1eb_, d1j1ec_, d1j1ee_, d1j1ef_
        complexed with ca; mutant
    5. Domain for 1lxf:
      • 355609Domain d1lxfc_: 1lxf C: [78292]
        Other proteins in same PDB: d1lxfi_
        N-domain only; complexed with a troponin I fragment
        complexed with bep, ca
    6. Domain for 1mxl:
      • 355610Domain d1mxlc_: 1mxl C: [17255]
        Other proteins in same PDB: d1mxli_
        N-domain only; complexed with a troponin I fragment
        complexed with ca
    7. Domain for 1ozs:
      • 355607Domain d1ozsa_: 1ozs A: [93857]
        N-domain only; complexed with a troponin I fragment; chain B
        complexed with ca
    8. Domain for 1spy:
  4. 355612Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47506] (4 PDB entries)
    1. Domain for 1a2x:
      • 355616Domain d1a2xa_: 1a2x A: [17251]
        Other proteins in same PDB: d1a2xb_
        complexed with a 47 residue (1-47) fragment of troponin I
        complexed with ca
    2. Domain for 1tcf:
      • 355615Domain d1tcf__: 1tcf - [17250]
        calcium-saturated form
        complexed with ca; mutant
    3. Domain for 1tn4:
    4. Domain for 2tn4:
  5. 355617Turkey (Meleagris gallopavo) [TaxId:9103] [47505] (2 PDB entries)
    1. Domain for 1trf:
    2. Domain for 5tnc:

More info for Protein Troponin C from a.39.1.5: Calmodulin-like

Timeline for Protein Troponin C from a.39.1.5: Calmodulin-like: