Lineage for Family a.39.1.5: Calmodulin-like

  1. Root: SCOPe 2.02
  2. 1074916Class a: All alpha proteins [46456] (284 folds)
  3. 1087624Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 1087625Superfamily a.39.1: EF-hand [47473] (12 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 1087980Family a.39.1.5: Calmodulin-like [47502] (24 proteins)
    Duplication: made with two pairs of EF-hands

Proteins:

  1. 1087981Calcineurin B-like protein 2 [101182] (1 species)
  2. 1087985Calcineurin regulatory subunit (B-chain) [47530] (2 species)
    1. 1087986Species Cow (Bos taurus) [TaxId:9913] [47531] (1 PDB entry)
    2. 1087988Species Human (Homo sapiens) [TaxId:9606] [47532] (5 PDB entries)
  3. 1087996Calcium vector protein [47514] (1 species)
  4. 1088002Calcium- and integrin-binding protein, CIB [47541] (1 species)
  5. 1088008Calcium-dependent protein kinase sk5 CLD [109821] (1 species)
  6. 1088012Calcium-regulated photoprotein [47512] (4 species)
    structurally most similar to sarcoplasmic calcium-binding protein
    1. 1088013Species Hydrozoa (Obelia geniculata), obelin [TaxId:185004] [63542] (1 PDB entry)
    2. 1088015Species Hydrozoa (Obelia longissima), obelin [TaxId:32570] [63541] (8 PDB entries)
      Uniprot Q27709
    3. 1088024Species Jellyfish (Aequorea aequorea), aequorin [TaxId:168712] [47513] (1 PDB entry)
    4. 1088027Species Jellyfish (Aequorea victoria), aequorin 1 [TaxId:6100] [116901] (1 PDB entry)
      Uniprot P07164 16-196
  7. 1088029Calerythrin [101179] (1 species)
    structurally most similar to sarcoplasmic calcium-binding protein
  8. 1088032Calmodulin [47516] (11 species)
    1. 1088033Species African clawed frog (Xenopus laevis) [TaxId:8355] [47521] (14 PDB entries)
    2. 1088053Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89052] (4 PDB entries)
    3. 1088058Species Chicken (Gallus gallus) [TaxId:9031] [47520] (7 PDB entries)
      mutant with a two residue deletion in the central helix
    4. 1088068Species Ciliate (Paramecium tetraurelia) [TaxId:5888] [47523] (4 PDB entries)
      Uniprot Q42478
    5. 1088074Species Cow (Bos taurus) [TaxId:9913] [47518] (19 PDB entries)
      Uniprot P62157
    6. 1088098Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [47522] (11 PDB entries)
    7. 1088114Species Human (Homo sapiens) [TaxId:9606] [47517] (48 PDB entries)
      Uniprot P02593
    8. 1088234Species Nematode (Caenorhabditis elegans) [TaxId:6239] [89051] (1 PDB entry)
    9. 1088236Species Norway rat (Rattus norvegicus) [TaxId:10116] [158477] (6 PDB entries)
    10. 1088244Species Potato (Solanum tuberosum) [TaxId:4113] [109820] (1 PDB entry)
    11. 1088246Species Rat (Rattus rattus) [TaxId:10117] [47519] (5 PDB entries)
      Uniprot P62161
  9. 1088266Calmodulin-related protein NB-1 (CLP) [74721] (1 species)
  10. 1088269Calmodulin-related protein T21P5.17 [109823] (1 species)
  11. 1088272Caltractin (centrin 2) [89053] (2 species)
    1. 1088273Species Green alga (Chlamydomonas reinhardtii) [TaxId:3055] [89055] (1 PDB entry)
    2. 1088275Species Human (Homo sapiens) [TaxId:9606] [89054] (5 PDB entries)
  12. 1088281Cdc4p [63543] (1 species)
  13. 1088284EHCABP [69021] (1 species)
  14. 1088290Frequenin (neuronal calcium sensor 1) [47535] (2 species)
    1. 1088291Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [47536] (2 PDB entries)
    2. 1088294Species Human (Homo sapiens) [TaxId:9606] [63545] (1 PDB entry)
  15. 1088297Guanylate cyclase activating protein 2, GCAP-2 [47537] (1 species)
  16. 1088300Kchip1, Kv4 potassium channel-interacting protein [101184] (2 species)
    1. 1088301Species Human (Homo sapiens) [TaxId:9606] [116902] (1 PDB entry)
      Uniprot Q9NZI2
    2. 1088303Species Norway rat (Rattus norvegicus) [TaxId:10116] [101185] (1 PDB entry)
  17. 1088305Myosin Essential Chain [47524] (3 species)
    1. 1088306Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47525] (13 PDB entries)
      Uniprot P13543
    2. 1088321Species Chicken (Gallus gallus) [TaxId:9031] [47526] (4 PDB entries)
    3. 1088333Species Human (Homo sapiens) [TaxId:9606] [101181] (2 PDB entries)
  18. 1088336Myosin Light Chain Mlc1p [81756] (1 species)
    light chain of class V myosin
  19. 1088342Myosin Regulatory Chain [47527] (2 species)
    1. 1088343Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47528] (15 PDB entries)
      Uniprot P07291
    2. 1088360Species Chicken (Gallus gallus) [TaxId:9031] [47529] (1 PDB entry)
  20. 1088362Neurocalcin [47539] (1 species)
  21. 1088366Recoverin [47533] (1 species)
    Calcium-myristoyl switch; only one EF-hand is functional
  22. 1088379Sarcoplasmic calcium-binding protein [47509] (2 species)
    1. 1088380Species Amphioxus (Branchiostoma lanceolatum) [TaxId:7740] [47511] (1 PDB entry)
    2. 1088382Species Sandworm (Nereis diversicolor) [TaxId:126592] [47510] (2 PDB entries)
      Uniprot P04571
  23. 1088386Troponin C [47503] (6 species)
    1. 1088387Species Chicken (Gallus gallus) [TaxId:9031] [47504] (28 PDB entries)
      Uniprot P09860
    2. 1088419Species Chicken (Gallus gallus), cardiac isoform [TaxId:9031] [47507] (1 PDB entry)
    3. 1088421Species Human (Homo sapiens), cardiac isoform [TaxId:9606] [47508] (15 PDB entries)
    4. 1088445Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47506] (4 PDB entries)
    5. 1088450Species Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [109819] (2 PDB entries)
      Uniprot Q7ZZB9 1-89
    6. 1088453Species Turkey (Meleagris gallopavo) [TaxId:9103] [47505] (2 PDB entries)
  24. 1088456automated matches [190064] (11 species)
    not a true protein
    1. 1088457Species Arabidopsis thaliana [TaxId:3702] [194524] (1 PDB entry)
    2. 1088460Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [188855] (2 PDB entries)
    3. 1088466Species Bay scallop (Argopecten irradians) [TaxId:31199] [189156] (2 PDB entries)
    4. 1088469Species Chicken (Gallus gallus) [TaxId:9031] [187205] (1 PDB entry)
    5. 1088471Species Human (Homo sapiens) [TaxId:9606] [186813] (7 PDB entries)
    6. 1088480Species Jellyfish (Aequorea victoria) [TaxId:6100] [186782] (4 PDB entries)
    7. 1088489Species Kluyveromyces lactis [TaxId:284590] [195890] (1 PDB entry)
    8. 1088494Species Mouse (Mus musculus) [TaxId:10090] [187204] (1 PDB entry)
    9. 1088497Species Placopecten magellanicus [TaxId:6577] [189594] (3 PDB entries)
    10. 1088510Species Scherffelia dubia [TaxId:3190] [189616] (1 PDB entry)
    11. 1088513Species Todarodes pacificus [TaxId:6637] [189006] (1 PDB entry)

More info for Family a.39.1.5: Calmodulin-like

Timeline for Family a.39.1.5: Calmodulin-like: