Lineage for Protein: Calcyclin (S100)

  1. Root: SCOPe 2.02
  2. 1074916Class a: All alpha proteins [46456] (284 folds)
  3. 1087624Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 1087625Superfamily a.39.1: EF-hand [47473] (12 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 1087651Family a.39.1.2: S100 proteins [47478] (2 proteins)
    dimer: subunits are made of two EF-hands
  6. 1087652Protein Calcyclin (S100) [47479] (17 species)

Species:

  1. 1087653Cow (Bos taurus), s100b [TaxId:9913] [47482] (15 PDB entries)
    1. Domains for 1cfp:
      1. 1087675Domain d1cfpa_: 1cfp A: [17172]
      2. 1087676Domain d1cfpb_: 1cfp B: [17173]
    2. Domain for 1mho:
    3. Domains for 1psb:
      1. 1087673Domain d1psba_: 1psb A: [95079]
        complexed with a peptide from Ndr kinase, chains C and D
      2. 1087674Domain d1psbb_: 1psb B: [95080]
        complexed with a peptide from Ndr kinase, chains C and D
    4. Domain for 3cr2:
    5. Domain for 3cr4:
    6. Domain for 3cr5:
    7. Domain for 3gk1:
    8. Domain for 3gk2:
    9. Domain for 3gk4:
    10. Domains for 3iqo:
      1. 1087654Domain d3iqoa_: 3iqo A: [178561]
        automated match to d1cfpa_
        complexed with ca
      2. 1087655Domain d3iqob_: 3iqo B: [178562]
        automated match to d1cfpa_
        complexed with ca
    11. Domain for 3iqq:
    12. Domains for 3lk0:
      1. 1087669Domain d3lk0a_: 3lk0 A: [180332]
        automated match to d3cr2a1
        complexed with ca, z80
      2. 1087670Domain d3lk0b_: 3lk0 B: [180333]
        automated match to d3cr2a1
        complexed with ca, z80
      3. 1087671Domain d3lk0c_: 3lk0 C: [180334]
        automated match to d3cr2a1
        complexed with ca, z80
      4. 1087672Domain d3lk0d_: 3lk0 D: [180335]
        automated match to d3cr2a1
        complexed with ca, z80
    13. Domain for 3lk1:
    14. Domains for 3lle:
      1. 1087658Domain d3llea_: 3lle A: [180370]
        automated match to d1cfpa_
        complexed with ca, sge
      2. 1087659Domain d3lleb_: 3lle B: [180371]
        automated match to d1cfpa_
        complexed with ca, sge
    15. Domains for 3rlz:
      1. 1087664Domain d3rlza_: 3rlz A: [195532]
        automated match to d1cfpa_
        complexed with ca
      2. 1087665Domain d3rlzb_: 3rlz B: [195533]
        automated match to d1cfpa_
        complexed with ca
  2. 1087677Human (Homo sapiens), calgranulin C, s100a12 [TaxId:9606] [47488] (3 PDB entries)
    1. Domains for 1e8a:
      1. 1087678Domain d1e8aa_: 1e8a A: [17188]
        complexed with ca
      2. 1087679Domain d1e8ab_: 1e8a B: [17189]
        complexed with ca
    2. Domains for 1gqm:
      1. 1087686Domain d1gqma_: 1gqm A: [70360]
        structure in a hexameric form
        complexed with ca
      2. 1087687Domain d1gqmb_: 1gqm B: [70361]
        structure in a hexameric form
        complexed with ca
      3. 1087688Domain d1gqmc_: 1gqm C: [70362]
        structure in a hexameric form
        complexed with ca
      4. 1087689Domain d1gqmd_: 1gqm D: [70363]
        structure in a hexameric form
        complexed with ca
      5. 1087690Domain d1gqme_: 1gqm E: [70364]
        structure in a hexameric form
        complexed with ca
      6. 1087691Domain d1gqmf_: 1gqm F: [70365]
        structure in a hexameric form
        complexed with ca
      7. 1087692Domain d1gqmg_: 1gqm G: [70366]
        structure in a hexameric form
        complexed with ca
      8. 1087693Domain d1gqmh_: 1gqm H: [70367]
        structure in a hexameric form
        complexed with ca
      9. 1087694Domain d1gqmi_: 1gqm I: [70368]
        structure in a hexameric form
        complexed with ca
      10. 1087695Domain d1gqmj_: 1gqm J: [70369]
        structure in a hexameric form
        complexed with ca
      11. 1087696Domain d1gqmk_: 1gqm K: [70370]
        structure in a hexameric form
        complexed with ca
      12. 1087697Domain d1gqml_: 1gqm L: [70371]
        structure in a hexameric form
        complexed with ca
    3. Domains for 1odb:
      1. 1087680Domain d1odba_: 1odb A: [86840]
        complexed with ca, cu
      2. 1087681Domain d1odbb_: 1odb B: [86841]
        complexed with ca, cu
      3. 1087682Domain d1odbc_: 1odb C: [86842]
        complexed with ca, cu
      4. 1087683Domain d1odbd_: 1odb D: [86843]
        complexed with ca, cu
      5. 1087684Domain d1odbe_: 1odb E: [86844]
        complexed with ca, cu
      6. 1087685Domain d1odbf_: 1odb F: [86845]
        complexed with ca, cu
  3. 1087698Human (Homo sapiens), calgranulin s100a8, MRP8 [TaxId:9606] [47487] (2 PDB entries)
    Migration inhibitory factor-related protein 8
    1. Domains for 1mr8:
      1. 1087705Domain d1mr8a_: 1mr8 A: [17186]
        complexed with ca
      2. 1087706Domain d1mr8b_: 1mr8 B: [17187]
        complexed with ca
    2. Domains for 1xk4:
      1. 1087699Domain d1xk4a1: 1xk4 A:1-87 [122055]
        complexed with ca, cl, flc
      2. 1087700Domain d1xk4b_: 1xk4 B: [122056]
        automated match to d1mr8a_
        complexed with ca, cl, flc
      3. 1087701Domain d1xk4e_: 1xk4 E: [122059]
        automated match to d1mr8a_
        complexed with ca, cl, flc
      4. 1087702Domain d1xk4f_: 1xk4 F: [122060]
        automated match to d1mr8a_
        complexed with ca, cl, flc
      5. 1087703Domain d1xk4i_: 1xk4 I: [122063]
        automated match to d1mr8a_
        complexed with ca, cl, flc
      6. 1087704Domain d1xk4j_: 1xk4 J: [122064]
        automated match to d1mr8a_
        complexed with ca, cl, flc
  4. 1087707Human (Homo sapiens), P11 s100a10, calpactin [TaxId:9606] [47484] (2 PDB entries)
    ligand of annexin II
    1. Domains for 1a4p:
      1. 1087708Domain d1a4pa_: 1a4p A: [17176]
      2. 1087709Domain d1a4pb_: 1a4p B: [17177]
    2. Domains for 1bt6:
      1. 1087710Domain d1bt6a_: 1bt6 A: [17178]
      2. 1087711Domain d1bt6b_: 1bt6 B: [17179]
  5. 1087712Human (Homo sapiens), psoriasin s100a7 [TaxId:9606] [47485] (3 PDB entries)
    1. Domains for 1psr:
      1. 1087713Domain d1psra_: 1psr A: [17180]
        complexed with ho
      2. 1087714Domain d1psrb_: 1psr B: [17181]
        complexed with ho
    2. Domain for 2psr:
    3. Domains for 3psr:
      1. 1087716Domain d3psra_: 3psr A: [17183]
        complexed with ca, zn
      2. 1087717Domain d3psrb_: 3psr B: [17184]
        complexed with ca, zn
  6. 1087718Human (Homo sapiens), s100a13 [TaxId:9606] [140535] (5 PDB entries)
    Uniprot Q99584 1-98
    1. Domains for 1yur:
      1. 1087722Domain d1yura1: 1yur A:1-98 [124062]
      2. 1087723Domain d1yurb1: 1yur B:1-98 [124063]
        automatically matched to 1YUR A:1-98
    2. Domains for 1yus:
      1. 1087726Domain d1yusa1: 1yus A:1-98 [124064]
        automatically matched to 1YUR A:1-98
      2. 1087727Domain d1yusb1: 1yus B:1-98 [124065]
        automatically matched to 1YUR A:1-98
    3. Domains for 1yut:
      1. 1087720Domain d1yuta1: 1yut A:1-98 [124066]
        automatically matched to 1YUR A:1-98
        complexed with ca
      2. 1087721Domain d1yutb1: 1yut B:1-98 [124067]
        automatically matched to 1YUR A:1-98
        complexed with ca
    4. Domains for 1yuu:
      1. 1087724Domain d1yuua1: 1yuu A:1-98 [124068]
        automatically matched to 1YUR A:1-98
        complexed with ca
      2. 1087725Domain d1yuub1: 1yuu B:1-98 [124069]
        automatically matched to 1YUR A:1-98
        complexed with ca
    5. Domain for 2egd:
  7. 1087728Human (Homo sapiens), s100a3 [TaxId:9606] [74720] (1 PDB entry)
  8. 1087731Human (Homo sapiens), s100a4 [TaxId:9606] [81754] (6 PDB entries)
    MTS1 protein
    1. Domains for 1m31:
      1. 1087770Domain d1m31a_: 1m31 A: [78506]
      2. 1087771Domain d1m31b_: 1m31 B: [78507]
    2. Domains for 2q91:
      1. 1087732Domain d2q91a_: 2q91 A: [150135]
        automated match to d1m31a_
        complexed with ca
      2. 1087733Domain d2q91b_: 2q91 B: [150136]
        automated match to d1m31a_
        complexed with ca
    3. Domains for 3cga:
      1. 1087758Domain d3cgaa_: 3cga A: [156615]
        automated match to d1m31a_
        complexed with ca
      2. 1087759Domain d3cgab_: 3cga B: [156616]
        automated match to d1m31a_
        complexed with ca
    4. Domains for 3ko0:
      1. 1087734Domain d3ko0a_: 3ko0 A: [179479]
        automated match to d1m31a_
        complexed with ca, tfp
      2. 1087735Domain d3ko0b_: 3ko0 B: [179480]
        automated match to d1m31a_
        complexed with ca, tfp
      3. 1087736Domain d3ko0c_: 3ko0 C: [179481]
        automated match to d1m31a_
        complexed with ca, tfp
      4. 1087737Domain d3ko0d_: 3ko0 D: [179482]
        automated match to d1m31a_
        complexed with ca, tfp
      5. 1087738Domain d3ko0e_: 3ko0 E: [179483]
        automated match to d1m31a_
        complexed with ca, tfp
      6. 1087739Domain d3ko0f_: 3ko0 F: [179484]
        automated match to d1m31a_
        complexed with ca, tfp
      7. 1087740Domain d3ko0g_: 3ko0 G: [179485]
        automated match to d1m31a_
        complexed with ca, tfp
      8. 1087741Domain d3ko0h_: 3ko0 H: [179486]
        automated match to d1m31a_
        complexed with ca, tfp
      9. 1087742Domain d3ko0i_: 3ko0 I: [179487]
        automated match to d1m31a_
        complexed with ca, tfp
      10. 1087743Domain d3ko0j_: 3ko0 J: [179488]
        automated match to d1m31a_
        complexed with ca, tfp
      11. 1087744Domain d3ko0k_: 3ko0 K: [179489]
        automated match to d1m31a_
        complexed with ca, tfp
      12. 1087745Domain d3ko0l_: 3ko0 L: [179490]
        automated match to d1m31a_
        complexed with ca, tfp
      13. 1087746Domain d3ko0m_: 3ko0 M: [179491]
        automated match to d1m31a_
        complexed with ca, tfp
      14. 1087747Domain d3ko0n_: 3ko0 N: [179492]
        automated match to d1m31a_
        complexed with ca, tfp
      15. 1087748Domain d3ko0o_: 3ko0 O: [179493]
        automated match to d1m31a_
        complexed with ca, tfp
      16. 1087749Domain d3ko0p_: 3ko0 P: [179494]
        automated match to d1m31a_
        complexed with ca, tfp
      17. 1087750Domain d3ko0q_: 3ko0 Q: [179495]
        automated match to d1m31a_
        complexed with ca, tfp
      18. 1087751Domain d3ko0r_: 3ko0 R: [179496]
        automated match to d1m31a_
        complexed with ca, tfp
      19. 1087752Domain d3ko0s_: 3ko0 S: [179497]
        automated match to d1m31a_
        complexed with ca, tfp
      20. 1087753Domain d3ko0t_: 3ko0 T: [179498]
        automated match to d1m31a_
        complexed with ca, tfp
    5. Domains for 3m0w:
      1. 1087760Domain d3m0wa_: 3m0w A: [180690]
        automated match to d1m31a_
        complexed with ca, dio, p77
      2. 1087761Domain d3m0wb_: 3m0w B: [180691]
        automated match to d1m31a_
        complexed with ca, dio, p77
      3. 1087762Domain d3m0wc_: 3m0w C: [180692]
        automated match to d1m31a_
        complexed with ca, dio, p77
      4. 1087763Domain d3m0wd_: 3m0w D: [180693]
        automated match to d1m31a_
        complexed with ca, dio, p77
      5. 1087764Domain d3m0we_: 3m0w E: [180694]
        automated match to d1m31a_
        complexed with ca, dio, p77
      6. 1087765Domain d3m0wf_: 3m0w F: [180695]
        automated match to d1m31a_
        complexed with ca, dio, p77
      7. 1087766Domain d3m0wg_: 3m0w G: [180696]
        automated match to d1m31a_
        complexed with ca, dio, p77
      8. 1087767Domain d3m0wh_: 3m0w H: [180697]
        automated match to d1m31a_
        complexed with ca, dio, p77
      9. 1087768Domain d3m0wi_: 3m0w I: [180698]
        automated match to d1m31a_
        complexed with ca, dio, p77
      10. 1087769Domain d3m0wj_: 3m0w J: [180699]
        automated match to d1m31a_
        complexed with ca, dio, p77
    6. Domains for 4hsz:
      1. 1087754Domain d4hsza_: 4hsz A: [194057]
        automated match to d1m31a_
        complexed with ca
      2. 1087755Domain d4hszb_: 4hsz B: [194056]
        automated match to d1m31a_
        complexed with ca
      3. 1087756Domain d4hszc_: 4hsz C: [194055]
        automated match to d1m31a_
        complexed with ca
      4. 1087757Domain d4hszd_: 4hsz D: [194058]
        automated match to d1m31a_
        complexed with ca
  9. 1087772Human (Homo sapiens), s100a6 [TaxId:9606] [74719] (4 PDB entries)
    1. Domain for 1k8u:
    2. Domain for 1k96:
    3. Domains for 1k9k:
      1. 1087775Domain d1k9ka_: 1k9k A: [72206]
        complexed with bme, ca
      2. 1087776Domain d1k9kb_: 1k9k B: [72207]
        complexed with bme, ca
    4. Domain for 1k9p:
  10. 1087778Human (Homo sapiens), s100a9 (mrp14) [TaxId:9606] [69020] (2 PDB entries)
    1. Domains for 1irj:
      1. 1087785Domain d1irja_: 1irj A: [66289]
        complexed with ca, cps
      2. 1087786Domain d1irjb_: 1irj B: [66290]
        complexed with ca, cps
      3. 1087787Domain d1irjc_: 1irj C: [66291]
        complexed with ca, cps
      4. 1087788Domain d1irjd_: 1irj D: [66292]
        complexed with ca, cps
      5. 1087789Domain d1irje_: 1irj E: [66293]
        complexed with ca, cps
      6. 1087790Domain d1irjf_: 1irj F: [66294]
        complexed with ca, cps
      7. 1087791Domain d1irjg_: 1irj G: [66295]
        complexed with ca, cps
      8. 1087792Domain d1irjh_: 1irj H: [66296]
        complexed with ca, cps
    2. Domains for 1xk4:
      1. 1087779Domain d1xk4c1: 1xk4 C:4-86 [122057]
        automatically matched to d1irja_
        complexed with ca, cl, flc
      2. 1087780Domain d1xk4d1: 1xk4 D:4-86 [122058]
        automatically matched to d1irja_
        complexed with ca, cl, flc
      3. 1087781Domain d1xk4g1: 1xk4 G:4-86 [122061]
        automatically matched to d1irja_
        complexed with ca, cl, flc
      4. 1087782Domain d1xk4h1: 1xk4 H:4-86 [122062]
        automatically matched to d1irja_
        complexed with ca, cl, flc
      5. 1087783Domain d1xk4k1: 1xk4 K:4-86 [122065]
        automatically matched to d1irja_
        complexed with ca, cl, flc
      6. 1087784Domain d1xk4l1: 1xk4 L:4-86 [122066]
        automatically matched to d1irja_
        complexed with ca, cl, flc
  11. 1087793Human (Homo sapiens), s100b [TaxId:9606] [47483] (6 PDB entries)
    1. Domains for 1mq1:
      1. 1087803Domain d1mq1a_: 1mq1 A: [79392]
        complex with high-affinity target peptide trtk-12, chains C and D
      2. 1087804Domain d1mq1b_: 1mq1 B: [79393]
        complex with high-affinity target peptide trtk-12, chains C and D
    2. Domains for 1uwo:
      1. 1087801Domain d1uwoa_: 1uwo A: [17174]
      2. 1087802Domain d1uwob_: 1uwo B: [17175]
    3. Domains for 2pru:
      1. 1087799Domain d2prua1: 2pru A:1-91 [149815]
        automatically matched to d1mq1a_
      2. 1087800Domain d2prub1: 2pru B:1-91 [149816]
        automatically matched to d1mq1a_
    4. Domain for 3czt:
    5. Domains for 3d0y:
      1. 1087795Domain d3d0ya_: 3d0y A: [173606]
        automated match to d1mq1a_
        complexed with ca, pg4, zn
      2. 1087796Domain d3d0yb_: 3d0y B: [173607]
        automated match to d1mq1a_
        complexed with ca, pg4, zn
    6. Domains for 3d10:
      1. 1087797Domain d3d10a_: 3d10 A: [173608]
        automated match to d1mq1a_
        complexed with ca, pge, zn
      2. 1087798Domain d3d10b_: 3d10 B: [173609]
        automated match to d1mq1a_
        complexed with ca, pge, zn
  12. 1087805Human (Homo sapiens), s100p [TaxId:9606] [81755] (2 PDB entries)
    1. Domain for 1j55:
    2. Domains for 1ozo:
      1. 1087807Domain d1ozoa_: 1ozo A: [93851]
      2. 1087808Domain d1ozob_: 1ozo B: [93852]
  13. 1087809Pig (Sus scrofa), calgizzarin s100c (s100a11) [TaxId:9823] [47486] (1 PDB entry)
    • Domain for 1qls:
      • 1087810Domain d1qlsa_: 1qls A: [17185]
        complex with annexin I N-terminus
        complexed with ca
  14. 1087811Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47480] (5 PDB entries)
    1. Domains for 1a03:
      1. 1087812Domain d1a03a_: 1a03 A: [17157]
      2. 1087813Domain d1a03b_: 1a03 B: [17158]
    2. Domains for 1cnp:
      1. 1087820Domain d1cnpa_: 1cnp A: [17161]
      2. 1087821Domain d1cnpb_: 1cnp B: [17162]
    3. Domains for 1jwd:
      1. 1087816Domain d1jwda_: 1jwd A: [71908]
      2. 1087817Domain d1jwdb_: 1jwd B: [71909]
    4. Domains for 2cnp:
      1. 1087818Domain d2cnpa_: 2cnp A: [17159]
      2. 1087819Domain d2cnpb_: 2cnp B: [17160]
    5. Domains for 2jtt:
      1. 1087814Domain d2jtta1: 2jtt A:1-90 [148205]
        automatically matched to d1a03a_
      2. 1087815Domain d2jttb1: 2jtt B:1-90 [148206]
        automatically matched to d1a03a_
  15. 1087822Rabbit (Oryctolagus cuniculus), calgizzarin s100a11 [TaxId:9986] [89047] (1 PDB entry)
  16. 1087825Rat (Rattus norvegicus), s100a1 [TaxId:10116] [69019] (3 PDB entries)
    1. Domains for 1k2h:
      1. 1087830Domain d1k2ha_: 1k2h A: [68056]
        apo-form
      2. 1087831Domain d1k2hb_: 1k2h B: [68057]
        apo-form
    2. Domains for 1zfs:
      1. 1087828Domain d1zfsa1: 1zfs A:1-93 [125003]
        automatically matched to d1k2ha_
        complexed with ca
      2. 1087829Domain d1zfsb1: 1zfs B:1-93 [125004]
        automatically matched to d1k2ha_
        complexed with ca
    3. Domains for 2k2f:
      1. 1087826Domain d2k2fa1: 2k2f A:1-93 [148258]
        automatically matched to d1k2ha_
        complexed with ca
      2. 1087827Domain d2k2fb1: 2k2f B:1-93 [148259]
        automatically matched to d1k2ha_
        complexed with ca
  17. 1087832Rat (Rattus norvegicus), s100b [TaxId:10116] [47481] (6 PDB entries)
    1. Domains for 1b4c:
      1. 1087839Domain d1b4ca_: 1b4c A: [17169]
      2. 1087840Domain d1b4cb_: 1b4c B: [17170]
    2. Domains for 1dt7:
      1. 1087837Domain d1dt7a_: 1dt7 A: [17165]
        Other proteins in same PDB: d1dt7x_, d1dt7y_
        complex with the C-terminal negative regulatory domain of p53
        complexed with ca
      2. 1087838Domain d1dt7b_: 1dt7 B: [17166]
        Other proteins in same PDB: d1dt7x_, d1dt7y_
        complex with the C-terminal negative regulatory domain of p53
        complexed with ca
    3. Domains for 1mwn:
      1. 1087835Domain d1mwna_: 1mwn A: [79584]
        complex with high-affinity target peptide trtk-12, chains X and Y
        complexed with ca
      2. 1087836Domain d1mwnb_: 1mwn B: [79585]
        complex with high-affinity target peptide trtk-12, chains X and Y
        complexed with ca
    4. Domains for 1qlk:
      1. 1087833Domain d1qlka_: 1qlk A: [17163]
        complexed with ca
      2. 1087834Domain d1qlkb_: 1qlk B: [17164]
        complexed with ca
    5. Domains for 1sym:
      1. 1087843Domain d1syma_: 1sym A: [17167]
      2. 1087844Domain d1symb_: 1sym B: [17168]
    6. Domains for 1xyd:
      1. 1087841Domain d1xyda1: 1xyd A:0-91 [122457]
        automatically matched to d1b4ca_
        complexed with ca, zn
      2. 1087842Domain d1xydb1: 1xyd B:0-91 [122458]
        automatically matched to d1b4ca_
        complexed with ca, zn

More info for Protein Calcyclin (S100) from a.39.1.2: S100 proteins

Timeline for Protein Calcyclin (S100) from a.39.1.2: S100 proteins: