SCOP 1.67: Protein: Calcyclin (S100)

Lineage for Protein: Calcyclin (S100)

Root: SCOP 1.67
Class a: All alpha proteins [46456] (202 folds)
Fold a.39: EF Hand-like [47472] (4 superfamilies)
core: 4 helices; array of 2 hairpins, opened
Superfamily a.39.1: EF-hand [47473] (10 families)
Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
Family a.39.1.2: S100 proteins [47478] (1 protein)
dimer: subunits are made of two EF-hands
Protein Calcyclin (S100) [47479] (16 species)

Species:

Cow (Bos taurus), s100b [TaxId:9913] [47482] (3 PDB entries)
1. Domains for 1cfp:
  1. Domain d1cfpa_: 1cfp A: [17172]
  2. Domain d1cfpb_: 1cfp B: [17173]
    mutant
2. Domain for 1mho:
  - Domain d1mho__: 1mho - [17171]
    complexed with ca
3. Domains for 1psb:
  1. Domain d1psba_: 1psb A: [95079]
  2. Domain d1psbb_: 1psb B: [95080]
    complexed with a peptide from Ndr kinase, chains C and D
Human (Homo sapiens), calgranulin C, s100a12 [TaxId:9606] [47488] (3 PDB entries)
1. Domains for 1e8a:
  1. Domain d1e8aa_: 1e8a A: [17188]
  2. Domain d1e8ab_: 1e8a B: [17189]
    complexed with ca
2. Domains for 1gqm:
  1. Domain d1gqma_: 1gqm A: [70360]
  2. Domain d1gqmb_: 1gqm B: [70361]
  3. Domain d1gqmc_: 1gqm C: [70362]
  4. Domain d1gqmd_: 1gqm D: [70363]
  5. Domain d1gqme_: 1gqm E: [70364]
  6. Domain d1gqmf_: 1gqm F: [70365]
  7. Domain d1gqmg_: 1gqm G: [70366]
  8. Domain d1gqmh_: 1gqm H: [70367]
  9. Domain d1gqmi_: 1gqm I: [70368]
  10. Domain d1gqmj_: 1gqm J: [70369]
  11. Domain d1gqmk_: 1gqm K: [70370]
  12. Domain d1gqml_: 1gqm L: [70371]
    structure in a hexameric form
    complexed with ca
3. Domains for 1odb:
  1. Domain d1odba_: 1odb A: [86840]
  2. Domain d1odbb_: 1odb B: [86841]
  3. Domain d1odbc_: 1odb C: [86842]
  4. Domain d1odbd_: 1odb D: [86843]
  5. Domain d1odbe_: 1odb E: [86844]
  6. Domain d1odbf_: 1odb F: [86845]
    complexed with ca, cu
Human (Homo sapiens), calgranulin s100a8, MRP8 [TaxId:9606] [47487] (1 PDB entry)
Migration inhibitory factor-related protein 8
- Domains for 1mr8:
  1. Domain d1mr8a_: 1mr8 A: [17186]
  2. Domain d1mr8b_: 1mr8 B: [17187]
    complexed with oc1
Human (Homo sapiens), P11 s100a10, calpactin [TaxId:9606] [47484] (2 PDB entries)
ligand of annexin II
1. Domains for 1a4p:
  1. Domain d1a4pa_: 1a4p A: [17176]
  2. Domain d1a4pb_: 1a4p B: [17177]
2. Domains for 1bt6:
  1. Domain d1bt6a_: 1bt6 A: [17178]
  2. Domain d1bt6b_: 1bt6 B: [17179]
    complexed with ace
Human (Homo sapiens), psoriasin s100a7 [TaxId:9606] [47485] (3 PDB entries)
1. Domains for 1psr:
  1. Domain d1psra_: 1psr A: [17180]
  2. Domain d1psrb_: 1psr B: [17181]
    complexed with ho
2. Domain for 2psr:
  - Domain d2psr__: 2psr - [17182]
    complexed with ca, zn
3. Domains for 3psr:
  1. Domain d3psra_: 3psr A: [17183]
  2. Domain d3psrb_: 3psr B: [17184]
    complexed with ca, zn
Human (Homo sapiens), s100a3 [TaxId:9606] [74720] (1 PDB entry)
- Domains for 1kso:
  1. Domain d1ksoa_: 1kso A: [72926]
  2. Domain d1ksob_: 1kso B: [72927]
Human (Homo sapiens), s100a4 [TaxId:9606] [81754] (1 PDB entry)
MTS1 protein
- Domains for 1m31:
  1. Domain d1m31a_: 1m31 A: [78506]
  2. Domain d1m31b_: 1m31 B: [78507]
Human (Homo sapiens), s100a6 [TaxId:9606] [74719] (4 PDB entries)
1. Domain for 1k8u:
  - Domain d1k8ua_: 1k8u A: [72181]
    complexed with mse; mutant
2. Domain for 1k96:
  - Domain d1k96a_: 1k96 A: [72187]
    complexed with bme, ca
3. Domains for 1k9k:
  1. Domain d1k9ka_: 1k9k A: [72206]
  2. Domain d1k9kb_: 1k9k B: [72207]
    complexed with bme, ca
4. Domain for 1k9p:
  - Domain d1k9pa_: 1k9p A: [72238]
    complexed with bme
Human (Homo sapiens), s100a9 (mrp14) [TaxId:9606] [69020] (1 PDB entry)
- Domains for 1irj:
  1. Domain d1irja_: 1irj A: [66289]
  2. Domain d1irjb_: 1irj B: [66290]
  3. Domain d1irjc_: 1irj C: [66291]
  4. Domain d1irjd_: 1irj D: [66292]
  5. Domain d1irje_: 1irj E: [66293]
  6. Domain d1irjf_: 1irj F: [66294]
  7. Domain d1irjg_: 1irj G: [66295]
  8. Domain d1irjh_: 1irj H: [66296]
    complexed with ca, cps
Human (Homo sapiens), s100b [TaxId:9606] [47483] (2 PDB entries)
1. Domains for 1mq1:
  1. Domain d1mq1a_: 1mq1 A: [79392]
  2. Domain d1mq1b_: 1mq1 B: [79393]
    complex with high-affinity target peptide trtk-12, chains C and D
2. Domains for 1uwo:
  1. Domain d1uwoa_: 1uwo A: [17174]
  2. Domain d1uwob_: 1uwo B: [17175]
Human (Homo sapiens), s100p [TaxId:9606] [81755] (2 PDB entries)
1. Domain for 1j55:
  - Domain d1j55a_: 1j55 A: [77078]
    complexed with ca
2. Domains for 1ozo:
  1. Domain d1ozoa_: 1ozo A: [93851]
  2. Domain d1ozob_: 1ozo B: [93852]
Pig (Sus scrofa), calgizzarin s100c (s100a11) [TaxId:9823] [47486] (1 PDB entry)
- Domain for 1qls:
  - Domain d1qlsa_: 1qls A: [17185]
    complex with annexin I N-terminus
    complexed with ace, ca
Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47480] (4 PDB entries)
1. Domains for 1a03:
  1. Domain d1a03a_: 1a03 A: [17157]
  2. Domain d1a03b_: 1a03 B: [17158]
2. Domains for 1cnp:
  1. Domain d1cnpa_: 1cnp A: [17161]
  2. Domain d1cnpb_: 1cnp B: [17162]
3. Domains for 1jwd:
  1. Domain d1jwda_: 1jwd A: [71908]
  2. Domain d1jwdb_: 1jwd B: [71909]
4. Domains for 2cnp:
  1. Domain d2cnpa_: 2cnp A: [17159]
  2. Domain d2cnpb_: 2cnp B: [17160]
Rabbit (Oryctolagus cuniculus), calgizzarin s100a11 [TaxId:9986] [89047] (1 PDB entry)
- Domains for 1nsh:
  1. Domain d1nsha_: 1nsh A: [86135]
  2. Domain d1nshb_: 1nsh B: [86136]
Rat (Rattus norvegicus), s100a1 [TaxId:10116] [69019] (1 PDB entry)
- Domains for 1k2h:
  1. Domain d1k2ha_: 1k2h A: [68056]
  2. Domain d1k2hb_: 1k2h B: [68057]
    apo-form
Rat (Rattus norvegicus), s100b [TaxId:10116] [47481] (5 PDB entries)
1. Domains for 1b4c:
  1. Domain d1b4ca_: 1b4c A: [17169]
  2. Domain d1b4cb_: 1b4c B: [17170]
2. Domains for 1dt7:
  1. Domain d1dt7a_: 1dt7 A: [17165]
    Other proteins in same PDB: d1dt7x_, d1dt7y_
  2. Domain d1dt7b_: 1dt7 B: [17166]
    Other proteins in same PDB: d1dt7x_, d1dt7y_
    complex with the C-terminal negative regulatory domain of p53
    complexed with ca
3. Domains for 1mwn:
  1. Domain d1mwna_: 1mwn A: [79584]
  2. Domain d1mwnb_: 1mwn B: [79585]
    complex with high-affinity target peptide trtk-12, chains X and Y
    complexed with ca
4. Domains for 1qlk:
  1. Domain d1qlka_: 1qlk A: [17163]
  2. Domain d1qlkb_: 1qlk B: [17164]
    complexed with ca
5. Domains for 1sym:
  1. Domain d1syma_: 1sym A: [17167]
  2. Domain d1symb_: 1sym B: [17168]

More info for Protein Calcyclin (S100) from a.39.1.2: S100 proteins

Timeline for Protein Calcyclin (S100) from a.39.1.2: S100 proteins:

Protein Calcyclin (S100) from a.39.1.2: S100 proteins first appeared (with stable ids) in SCOP 1.55
Protein Calcyclin (S100) from a.39.1.2: S100 proteins appears in SCOP 1.65
Protein Calcyclin (S100) from a.39.1.2: S100 proteins appears in SCOP 1.69
Protein Calcyclin (S100) from a.39.1.2: S100 proteins appears in the current release, SCOPe 2.08