Lineage for Superfamily a.39.1: EF-hand

  1. Root: SCOP 1.63
  2. 208553Class a: All alpha proteins [46456] (171 folds)
  3. 213166Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 213167Superfamily a.39.1: EF-hand [47473] (9 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

Families:

  1. 213168a.39.1.1: Calbindin D9K [47474] (1 protein)
    made of two EF-hands only
  2. 213190a.39.1.2: S100 proteins [47478] (1 protein)
    dimer: subunits are made of two EF-hands
  3. 213278a.39.1.3: Osteonectin [47489] (1 protein)
    5 helices; two EF-hands plus one of additional helices in the N-terminal part
  4. 213286a.39.1.4: Parvalbumin [47492] (2 proteins)
    6-helices; array of 3 hairpins, closed
    made with two-helical hairpin and two EF-hands
  5. 213324a.39.1.5: Calmodulin-like [47502] (17 proteins)
    Duplication: made with two pairs of EF-hands
  6. 213538a.39.1.6: Eps15 homology domain (EH domain) [47543] (3 proteins)
  7. 213553a.39.1.7: EF-hand modules in multidomain proteins [47547] (5 proteins)
  8. 213595a.39.1.8: Penta-EF-hand proteins [63550] (5 proteins)
  9. 213638a.39.1.9: Cbp40 (plasmodial specific CaII-binding protein LAV1-2) [81758] (1 protein)
    4 EF-hands assembled in a compact structure like the Penta-EF-hand proteins; contains additional N-terminal all-alpha subdomain

More info for Superfamily a.39.1: EF-hand

Timeline for Superfamily a.39.1: EF-hand: