SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family a.35.1.2: Phage repressors

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1993669Fold a.35: lambda repressor-like DNA-binding domains [47412] (1 superfamily)
    core: 4 helices; folded leaf, closed
  4. 1993670Superfamily a.35.1: lambda repressor-like DNA-binding domains [47413] (14 families) (S)
  5. 1993691Family a.35.1.2: Phage repressors [47419] (7 protein domains)
    consists of different sequence families of HTH repressors of phage origins

Protein Domains:

  1. 1993692434 C1 repressor, DNA-binding domain [47422] (1 species)
  2. 1993705cro 434 [47424] (1 species)
  3. 1993711cro lambda repressor [47428] (1 species)
    the fourth helix is replaced with a beta hairpin
    3 helices; folded leaf, opened
  4. 1993736cro p22 [109809] (1 species)
  5. 1993739lambda C1 repressor, DNA-binding domain [47420] (1 species)
  6. 1993752Ner [47430] (1 species)
  7. 1993756P22 C2 repressor, DNA-binding domain [47426] (1 species)

More info for Family a.35.1.2: Phage repressors

Timeline for Family a.35.1.2: Phage repressors: