SCOPe 2.07: Superfamily a.35.1: lambda repressor-like DNA-binding domains

Lineage for Superfamily a.35.1: lambda repressor-like DNA-binding domains

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.35: lambda repressor-like DNA-binding domains [47412] (1 superfamily)
   core: 4 helices; folded leaf, closed

4. Superfamily a.35.1: lambda repressor-like DNA-binding domains [47413] (14 families)

Families:

1. a.35.1.1: POU-specific domain [47414] (3 proteins)

2. a.35.1.2: Phage repressors [47419] (7 proteins)
   consists of different sequence families of HTH repressors of phage origins

3. a.35.1.3: SinR domain-like [47432] (9 proteins)

4. a.35.1.4: Cyanase N-terminal domain [47435] (2 proteins)
   probably does not bind to DNA

5. a.35.1.5: GalR/LacI-like bacterial regulator [47438] (4 proteins)
   lacks the first helix of canonical fold
   3 helices; bundle, partly opened, right-handed twist

6. a.35.1.6: YdiL-like [109813] (2 proteins)
   contains extra C-terminal all-alpha dimerization subdomain; the dimer may bind DNA

7. a.35.1.7: CUT domain [116891] (5 proteins)
   Pfam PF02376

8. a.35.1.8: Probable transcriptional regulator VC1968, N-terminal domain [116898] (1 protein)

9. a.35.1.9: Bacteriophage CII protein [140520] (1 protein)
   Pfam PF05269; a compact helix-swapped dimer of the canonical fold; includes the extra C-terminal teramerisation region (alpha-helix); in the tetramer-DNA complex only two of the four HTH motifs interact with DNA

10. a.35.1.10: NE0471 C-terminal domain-like [140523] (1 protein)

11. a.35.1.11: PrgX N-terminal domain-like [140526] (1 protein)
    Part of Pfam PF01381

12. a.35.1.12: EDF1-like [140529] (1 protein)
    part of Pfam PF01381

13. a.35.1.13: NE1354 [140532] (2 proteins)
    contains extra C-terminal dimerisation arm (beta-strand)
    automatically mapped to Pfam PF13744

14. a.35.1.0: automated matches [191534] (1 protein)
    not a true family

More info for Superfamily a.35.1: lambda repressor-like DNA-binding domains

Timeline for Superfamily a.35.1: lambda repressor-like DNA-binding domains:

• Superfamily a.35.1: lambda repressor-like DNA-binding domains first appeared (with stable ids) in SCOP 1.55
  
• Superfamily a.35.1: lambda repressor-like DNA-binding domains appears in SCOPe 2.06
  
• Superfamily a.35.1: lambda repressor-like DNA-binding domains appears in the current release, SCOPe 2.08