SCOPe 2.03: Fold a.34: Dimerisation interlock

Lineage for Fold a.34: Dimerisation interlock

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.34: Dimerisation interlock [47405] (4 superfamilies)
   4 helices; bundle, closed, right-handed twist

Superfamilies:

1. a.34.1: SinR repressor dimerisation domain-like [47406] (1 family)
   intertwined heterodimer of two homologous chains

2. a.34.2: Dimerization cofactor of HNF-1 alpha [100957] (1 family)
   automatically mapped to Pfam PF04814

3. a.34.3: Docking domain A of the erythromycin polyketide synthase (DEBS) [101166] (1 family)
   automatically mapped to Pfam PF09277

4. a.34.4: Phenylalanine zipper [109805] (1 family)
   interlocking dimer with longer helices and aromatic-rich core
   automatically mapped to Pfam PF08916

More info for Fold a.34: Dimerisation interlock

Timeline for Fold a.34: Dimerisation interlock:

• Fold a.34: Dimerisation interlock first appeared (with stable ids) in SCOP 1.55, called Fold a.34: SinR repressor dimerisation domain-like
  
• Fold a.34: Dimerisation interlock appears in SCOPe 2.02
  
• Fold a.34: Dimerisation interlock appears in SCOPe 2.04
  
• Fold a.34: Dimerisation interlock appears in the current release, SCOPe 2.08