SCOPe 2.03: Family a.27.1.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases

Lineage for Family a.27.1.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.27: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47322] (1 superfamily)
   core: 4 helices; bundle; one loop crosses over one side of the bundle

4. Superfamily a.27.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47323] (2 families)

5. Family a.27.1.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47324] (6 proteins)

Proteins:

1. Arginyl-tRNA synthetase (ArgRS) [47333] (2 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [47334] (3 PDB entries)

   2. Species Thermus thermophilus [TaxId:274] [69007] (1 PDB entry)

2. Cysteinyl-tRNA synthetase (CysRS) [74709] (1 species)
   contains extra C-terminal alpha+beta subdomain: [alpha(2)-beta(2)], ordered in the complex with tRNA

   • Species Escherichia coli [TaxId:562] [74710] (3 PDB entries)
     Uniprot P21888; extra C-terminal subdomain: 407-461

3. Isoleucyl-tRNA synthetase (IleRS) [47328] (2 species)

   1. Species Staphylococcus aureus [TaxId:1280] [47330] (3 PDB entries)
      contains additional alpha+beta and Zn-binding domains in the C-terminal extension

   2. Species Thermus thermophilus [TaxId:274] [47329] (3 PDB entries)

4. Leucyl-tRNA synthetase (LeuRS) [81746] (1 species)

   • Species Thermus thermophilus [TaxId:274] [81747] (3 PDB entries)

5. Methionyl-tRNA synthetase (MetRS) [47325] (3 species)
   this domain follows the Rossmann-fold catalytic domain of class I aaRS

   1. Species Escherichia coli [TaxId:562] [47327] (9 PDB entries)

   2. Species Pyrococcus abyssi [TaxId:29292] [109792] (1 PDB entry)
      Uniprot Q9V011 1-606 # C-domain 616-722 is solved separately: 1MKH

   3. Species Thermus thermophilus [TaxId:274] [47326] (4 PDB entries)

6. Valyl-tRNA synthetase (ValRS) [47331] (1 species)
   includes additional alpha+beta (sub)domain at the C-terminus

   • Species Thermus thermophilus [TaxId:274] [47332] (3 PDB entries)

More info for Family a.27.1.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases

Timeline for Family a.27.1.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases:

• Family a.27.1.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases first appeared (with stable ids) in SCOP 1.55
  
• Family a.27.1.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases appears in SCOPe 2.02
  
• Family a.27.1.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases appears in SCOPe 2.04
  
• Family a.27.1.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases appears in the current release, SCOPe 2.08