Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991729Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 protein domains)
    contains an additional helix in one of the crossover connections
  6. 1991730Protein Interferon-alpha 2a [47314] (1 species)
  7. 1991731Species Human (Homo sapiens) [TaxId:9606] [47315] (9 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1itf:
  2. Domain(s) for 2hym:
  3. Domain(s) for 2ksx:
  4. Domain(s) for 2kz1:
  5. Domain(s) for 2lag:
  6. Domain(s) for 2lms:
  7. Domain(s) for 3s9d:
    1. 1991732Domain d3s9da_: 3s9d A: [200600]
      Other proteins in same PDB: d3s9db1, d3s9db2, d3s9dd1, d3s9dd2
      automated match to d3s9dc_
      complexed with cl
    2. 1991733Domain d3s9dc_: 3s9d C: [196189]
      Other proteins in same PDB: d3s9db1, d3s9db2, d3s9dd1, d3s9dd2
      automated match to d1itfa_
      complexed with cl
  8. Domain(s) for 4ypg:
    1. 1991742Domain d4ypgc1: 4ypg C:1-157 [272489]
      Other proteins in same PDB: d4ypga1, d4ypga2, d4ypgc2, d4ypgd2, d4ypgl1, d4ypgl2
      automated match to d1itfa_
      complexed with ni
    2. 1991743Domain d4ypgd1: 4ypg D:1-159 [272488]
      Other proteins in same PDB: d4ypga1, d4ypga2, d4ypgc2, d4ypgd2, d4ypgl1, d4ypgl2
      automated match to d1itfa_
      complexed with ni
  9. Domain(s) for 4z5r:
    1. 1991734Domain d4z5rd_: 4z5r D: [274819]
      Other proteins in same PDB: d4z5ra1, d4z5ra2, d4z5rj1, d4z5rj2, d4z5rl1, d4z5rl2, d4z5rp1, d4z5rp2, d4z5rr1, d4z5rr2, d4z5rt1, d4z5rt2, d4z5rv1, d4z5rv2, d4z5ry_
      automated match to d1itfa_
      complexed with so4
    2. 1991735Domain d4z5re_: 4z5r E: [274818]
      Other proteins in same PDB: d4z5ra1, d4z5ra2, d4z5rj1, d4z5rj2, d4z5rl1, d4z5rl2, d4z5rp1, d4z5rp2, d4z5rr1, d4z5rr2, d4z5rt1, d4z5rt2, d4z5rv1, d4z5rv2, d4z5ry_
      automated match to d1itfa_
      complexed with so4
    3. 1991736Domain d4z5rf_: 4z5r F: [274816]
      Other proteins in same PDB: d4z5ra1, d4z5ra2, d4z5rj1, d4z5rj2, d4z5rl1, d4z5rl2, d4z5rp1, d4z5rp2, d4z5rr1, d4z5rr2, d4z5rt1, d4z5rt2, d4z5rv1, d4z5rv2, d4z5ry_
      automated match to d1itfa_
      complexed with so4
    4. 1991737Domain d4z5rg_: 4z5r G: [274817]
      Other proteins in same PDB: d4z5ra1, d4z5ra2, d4z5rj1, d4z5rj2, d4z5rl1, d4z5rl2, d4z5rp1, d4z5rp2, d4z5rr1, d4z5rr2, d4z5rt1, d4z5rt2, d4z5rv1, d4z5rv2, d4z5ry_
      automated match to d1itfa_
      complexed with so4
    5. 1991738Domain d4z5rh_: 4z5r H: [274820]
      Other proteins in same PDB: d4z5ra1, d4z5ra2, d4z5rj1, d4z5rj2, d4z5rl1, d4z5rl2, d4z5rp1, d4z5rp2, d4z5rr1, d4z5rr2, d4z5rt1, d4z5rt2, d4z5rv1, d4z5rv2, d4z5ry_
      automated match to d1itfa_
      complexed with so4
    6. 1991739Domain d4z5ri_: 4z5r I: [274821]
      Other proteins in same PDB: d4z5ra1, d4z5ra2, d4z5rj1, d4z5rj2, d4z5rl1, d4z5rl2, d4z5rp1, d4z5rp2, d4z5rr1, d4z5rr2, d4z5rt1, d4z5rt2, d4z5rv1, d4z5rv2, d4z5ry_
      automated match to d1itfa_
      complexed with so4
    7. 1991740Domain d4z5rn_: 4z5r N: [274822]
      Other proteins in same PDB: d4z5ra1, d4z5ra2, d4z5rj1, d4z5rj2, d4z5rl1, d4z5rl2, d4z5rp1, d4z5rp2, d4z5rr1, d4z5rr2, d4z5rt1, d4z5rt2, d4z5rv1, d4z5rv2, d4z5ry_
      automated match to d1itfa_
      complexed with so4
    8. 1991741Domain d4z5rx_: 4z5r X: [274831]
      Other proteins in same PDB: d4z5ra1, d4z5ra2, d4z5rj1, d4z5rj2, d4z5rl1, d4z5rl2, d4z5rp1, d4z5rp2, d4z5rr1, d4z5rr2, d4z5rt1, d4z5rt2, d4z5rv1, d4z5rv2, d4z5ry_
      automated match to d1itfa_
      complexed with so4

More info for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.3 Interferon-alpha 2a

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.3 Interferon-alpha 2a: