Class a: All alpha proteins [46456] (284 folds) |
Fold a.26: 4-helical cytokines [47265] (1 superfamily) core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections |
Superfamily a.26.1: 4-helical cytokines [47266] (3 families) there are two different topoisomers of this fold with different entanglements of the two crossover connections |
Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (8 proteins) contains an additional helix in one of the crossover connections |
Protein Interferon-beta [47309] (2 species) |
Human (Homo sapiens) [TaxId:9606] [47310] (1 PDB entry) |
Domain d1au1a_: 1au1 A: [16889] |
Domain d1au1b_: 1au1 B: [16890] complexed with fuc, gal, glc, man, zn |
Mouse (Mus musculus) [TaxId:10090] [47311] (2 PDB entries) Uniprot P01575 22-182 CA-atoms only |
Domain d1ifaa_: 1ifa A: [16892] CA-atoms only |
Domain d1wu3i_: 1wu3 I: [114890] |
Timeline for Protein Interferon-beta from a.26.1.3: Interferons/interleukin-10 (IL-10):