Lineage for Protein: Interferon-beta

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991729Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 protein domains)
    contains an additional helix in one of the crossover connections
  6. 1991758Protein Interferon-beta [47309] (2 species)

Species:

  1. 1991759Human (Homo sapiens) [TaxId:9606] [47310] (1 PDB entry)
  2. 1991762Mouse (Mus musculus) [TaxId:10090] [47311] (4 PDB entries)
    Uniprot P01575 22-182
    CA-atoms only
    1. Domain for 1ifa:
    2. Domain for 1rmi:
    3. Domain for 1wu3:
    4. Domain for 3wcy:

More info for Protein Interferon-beta from a.26.1.3: Interferons/interleukin-10 (IL-10)

Timeline for Protein Interferon-beta from a.26.1.3: Interferons/interleukin-10 (IL-10):