Class a: All alpha proteins [46456] (290 folds) |
Fold a.26: 4-helical cytokines [47265] (1 superfamily) core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections |
Superfamily a.26.1: 4-helical cytokines [47266] (4 families) there are two different topoisomers of this fold with different entanglements of the two crossover connections |
Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 proteins) contains an additional helix in one of the crossover connections |
Protein Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) [47306] (3 species) intertwined dimer, similar to interferon-gamma |
Species Epstein-Barr virus [TaxId:10376] [47308] (3 PDB entries) |
Domain d1vlka_: 1vlk A: [16888] |
Domain d1y6ml_: 1y6m L: [122665] Other proteins in same PDB: d1y6mr1, d1y6mr2 automated match to d1vlk__ |
Domain d1y6nl1: 1y6n L:12-157 [144600] Other proteins in same PDB: d1y6nr1, d1y6nr2 mutant |
Timeline for Species Epstein-Barr virus [TaxId:10376] from a.26.1.3 Interleukin-10 (cytokine synthesis inhibitory factor, CSIF):